Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
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| Title: | Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. |
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| Authors: | Kunkle BW; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA. bkunkle@miami.edu., Grenier-Boley B; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France., Sims R; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Damotte V; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France., Naj AC; Department of Biostatistics and Epidemiology/Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Boland A; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Vronskaya M; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., van der Lee SJ; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Amlie-Wolf A; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Bellenguez C; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France., Frizatti A; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Chouraki V; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France.; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Martin ER; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Sleegers K; Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Antwerp, Belgium.; Laboratory for Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium., Badarinarayan N; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Jakobsdottir J; Icelandic Heart Association, Kopavogur, Iceland., Hamilton-Nelson KL; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Moreno-Grau S; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., Olaso R; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Raybould R; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Chen Y; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Kuzma AB; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Hiltunen M; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland., Morgan T; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Ahmad S; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Vardarajan BN; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.; Department of Neurology, Columbia University, New York, NY, USA., Epelbaum J; UMR 894, Center for Psychiatry and Neuroscience, Inserm, Université Paris Descartes, Paris, France., Hoffmann P; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; Division of Medical Genetics, University Hospital and Department of Biomedicine, University of Basel, Basel, Switzerland., Boada M; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., Beecham GW; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Garnier JG; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Harold D; School of Biotechnology, Dublin City University, Dublin, Ireland., Fitzpatrick AL; Department of Family Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA., Valladares O; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Moutet ML; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Gerrish A; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Smith AV; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Qu L; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Bacq D; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Denning N; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Jian X; Brown Foundation Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, Houston, TX, USA., Zhao Y; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Del Zompo M; Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Fox NC; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Choi SH; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain., Mateo I; Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IDIVAL), Santander, Spain., Hughes JT; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Adams HH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Malamon J; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Sanchez-Garcia F; Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain., Patel Y; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Dombroski BA; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Naranjo MCD; Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain., Daniilidou M; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Mukherjee S; Department of Medicine, University of Washington, Seattle, WA, USA., Wallon D; Normandie University, UNIROUEN, Inserm U1245, and Rouen University Hospital, Department of Neurology, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Rouen, France., Uphill J; Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK., Aspelund T; Icelandic Heart Association, Kopavogur, Iceland.; Centre for Public Health, University of Iceland, Reykjavik, Iceland., Cantwell LB; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Garzia F; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Galimberti D; Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Neurodegenerative Diseases Unit, Milan, Italy.; University of Milan, Centro Dino Ferrari, Milan, Italy., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Butkiewicz M; Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Fin B; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Scarpini E; Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Neurodegenerative Diseases Unit, Milan, Italy.; University of Milan, Centro Dino Ferrari, Milan, Italy., Sarnowski C; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Bush WS; Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Meslage S; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Kornhuber J; Department of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, Germany., White CC; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Song Y; Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Barber RC; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA., Engelborghs S; Laboratory for Neurochemistry and Behavior, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.; Department of Neurology and Memory Clinic, Hospital Network Antwerp, Antwerp, Belgium., Sordon S; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany., Voijnovic D; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Adams PM; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA., Vandenberghe R; Laboratory for Cognitive Neurology, Department of Neurology, University Hospital and University of Leuven, Leuven, Belgium., Mayhaus M; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany., Cupples LA; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Albert MS; Department of Neurology, Johns Hopkins University, Baltimore, MD, USA., De Deyn PP; Laboratory for Neurochemistry and Behavior, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.; Department of Neurology and Memory Clinic, Hospital Network Antwerp, Antwerp, Belgium., Gu W; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany., Himali JJ; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Beekly D; National Alzheimer's Coordinating Center, University of Washington, Seattle, WA, USA., Squassina A; Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Hartmann AM; Department of Psychiatry, Martin Luther University Halle-Wittenberg, Halle, Germany., Orellana A; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain., Blacker D; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA., Rodriguez-Rodriguez E; Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IDIVAL), Santander, Spain., Lovestone S; Department of Psychiatry, University of Oxford, Oxford, UK., Garcia ME; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA., Doody RS; Alzheimer's Disease and Memory Disorders Center, Baylor College of Medicine, Houston, TX, USA., Munoz-Fernadez C; Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain., Sussams R; Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK., Lin H; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Fairchild TJ; Office of Strategy and Measurement, University of North Texas Health Science Center, Fort Worth, TX, USA., Benito YA; Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain., Holmes C; Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK., Karamujić-Čomić H; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Frosch MP; C.S. Kubik Laboratory for Neuropathology, Massachusetts General Hospital, Charlestown, MA, USA., Thonberg H; Theme Aging, Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden.; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Alzheimer Research Center, Division of Neurogeriatrics, Solna, Sweden., Maier W; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany., Roshchupkin G; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Ghetti B; Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN, USA., Giedraitis V; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden., Kawalia A; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany., Li S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Huebinger RM; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA., Kilander L; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden., Moebus S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany., Hernández I; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., Kamboh MI; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, USA., Brundin R; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden., Turton J; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK., Yang Q; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Katz MJ; Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA., Concari L; Section of Neuroscience, DIMEC-University of Parma, Parma, Italy.; FERB-Alzheimer Center, Gazzaniga (Bergamo), Italy., Lord J; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK., Beiser AS; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Keene CD; Department of Pathology, University of Washington, Seattle, WA, USA., Helisalmi S; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland., Kloszewska I; Elderly and Psychiatric Disorders Department, Medical University of Lodz, Lodz, Poland., Kukull WA; Department of Epidemiology, University of Washington, Seattle, WA, USA., Koivisto AM; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland., Lynch A; Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.; St. James's Hospital and Trinity College, Dublin, Ireland., Tarraga L; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., Larson EB; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Haapasalo A; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Lawlor B; Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.; St. James's Hospital and Trinity College, Dublin, Ireland., Mosley TH; Departments of Medicine, Geriatrics, Gerontology and Neurology, University of Mississippi Medical Center, Jackson, MS, USA., Lipton RB; Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA., Solfrizzi V; Interdisciplinary Department of Medicine, Geriatric Medicine and Memory Unity, University of Bari, Bari, Italy., Gill M; Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.; St. James's Hospital and Trinity College, Dublin, Ireland., Longstreth WT Jr; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Neurology, University of Washington, Seattle, WA, USA., Montine TJ; Department of Pathology, University of Washington, Seattle, WA, USA., Frisardi V; Department of Geriatrics, Center for Aging Brain, University of Bari, Bari, Italy., Diez-Fairen M; Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Terrassa, Barcelona, Spain.; Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain., Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdamt, the Netherlands.; Netherlands Consortium on Health Aging and National Genomics Initiative, Leiden, the Netherlands., Petersen RC; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Deramecourt V; CHU Lille, Memory Center of Lille (Centre Mémoire de Ressources et de Recherche), Lille, France., Alvarez I; Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Terrassa, Barcelona, Spain.; Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain., Salani F; Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy., Ciaramella A; Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy., Boerwinkle E; School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Reiman EM; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.; Arizona Alzheimer's Consortium, Phoenix, AZ, USA.; Banner Alzheimer's Institute, Phoenix, AZ, USA.; Department of Psychiatry, University of Arizona, Phoenix, AZ, USA., Fievet N; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France., Rotter JI; Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Reisch JS; Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA., Hanon O; University Paris Descartes, EA 4468, AP-HP, Geriatrics Department, Hôpital Broca, Paris, France., Cupidi C; Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy., Andre Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdamt, the Netherlands.; Netherlands Consortium on Health Aging and National Genomics Initiative, Leiden, the Netherlands., Royall DR; Departments of Psychiatry, Medicine, Family & Community Medicine, South Texas Veterans Health Administration Geriatric Research Education & Clinical Center (GRECC), UT Health Science Center at San Antonio, San Antonio, TX, USA., Dufouil C; University of Bordeaux, Inserm 1219, Bordeaux, France.; Department of Neurology, Bordeaux University Hospital / CHU de Bordeaux, Bordeaux, France., Maletta RG; Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy., de Rojas I; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., Sano M; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Brice A; Inserm U1127, CNRS UMR 7225, Sorbonne Universités, UPMC Université Paris 06, UMRS 1127, Institut du Cerveau et de la Moelle Épinière, Paris, France.; AP-HP, Department of Genetics, Pitié-Salpêtrière Hospital, Paris, France., Cecchetti R; Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy., George-Hyslop PS; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada., Ritchie K; Inserm U1061 Neuropsychiatry, La Colombière Hospital, Montpellier, France.; Montpellier University, Montpellier, France.; Department of Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK., Tsolaki M; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Tsuang DW; VA Puget Sound Health Care System/>GRECC, Seattle, WA, USA.; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA., Dubois B; Institut de la Mémoire et de la Maladie d'Alzheimer and Institut du Cerveau et de la Moelle Épinière, Département de Neurologie, Hôpital de la Pitié-Salpêtrière, Paris, France.; Institut des Neurosciences Translationnelles de Paris, Institut du Cerveau et de la Moelle Épinière, Paris, France.; Inserm, CNRS, UMR-S975, Institut du Cerveau et de la Moelle Epinière, Paris, France.; Sorbonne Universités, Université Pierre et Marie Curie, Hôpital de la Pitié-Salpêtrière, AP-HP, Paris, France., Craig D; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Wu CK; Departments of Neurology, Pharmacology & Neuroscience, Texas Tech University Health Science Center, Lubbock, TX, USA., Soininen H; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland., Avramidou D; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Albin RL; Department of Neurology, University of Michigan, Ann Arbor, MI, USA.; Geriatric Research, Education and Clinical Center (GRECC), VA Ann Arbor Healthcare System (VAAAHS), Ann Arbor, MI, USA.; Michigan Alzheimer Disease Center, Ann Arbor, MI, USA., Fratiglioni L; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden., Germanou A; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Apostolova LG; Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA.; Department of Neurology, Indiana University, Indianapolis, IN, USA.; Department of Radiology and Imaging Sciences, Indiana University, Indianapolis, IN, USA., Keller L; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden., Koutroumani M; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Arnold SE; Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Panza F; Department of Geriatrics, Center for Aging Brain, University of Bari, Bari, Italy., Gkatzima O; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Asthana S; Geriatric Research, Education and Clinical Center (GRECC), University of Wisconsin, Madison, WI, USA.; Department of Medicine, University of Wisconsin, Madison, WI, USA.; Wisconsin Alzheimer's Disease Research Center, Madison, WI, USA., Hannequin D; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Whitehead P; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Atwood CS; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA.; Department of Neurology, Indiana University, Indianapolis, IN, USA.; Department of Radiology and Imaging Sciences, Indiana University, Indianapolis, IN, USA., Caffarra P; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, USA.; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK., Hampel H; AXA Research Fund & Sorbonne University Chair, Paris, France.; Sorbonne University, GRC n° 21, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Paris, France.; Brain & Spine Institute, Inserm U 1127, CNRS UMR 7225, Paris, France.; Institute of Memory and Alzheimer's Disease, Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France., Quintela I; Grupo de Medicina Xenomica, Universidade de Santiago de Compostela, Centro Nacional de Genotipado, Centro de Investigación Biomédica en Red de Enfermedades Raras, Santiago de Compostela, Spain., Carracedo Á; Grupo de Medicina Xenomica, Universidade de Santiago de Compostela, Centro Nacional de Genotipado, Centro de Investigación Biomédica en Red de Enfermedades Raras, Santiago de Compostela, Spain., Lannfelt L; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden., Rubinsztein DC; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.; UK Dementia Research Institute, University of Cambridge, Cambridge, UK., Barnes LL; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Pasquier F; CHU Lille, Memory Center of Lille (Centre Mémoire de Ressources et de Recherche), Lille, France., Frölich L; Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Barral S; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.; Department of Neurology, Columbia University, New York, NY, USA., McGuinness B; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Beach TG; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Phoenix, AZ, USA., Johnston JA; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Becker JT; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Psychology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Passmore P; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Bigio EH; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Schott JM; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Bird TD; Department of Neurology, University of Washington, Seattle, WA, USA.; VA Puget Sound Health Care System/>GRECC, Seattle, WA, USA., Warren JD; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Boeve BF; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Lupton MK; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Bowen JD; Swedish Medical Center, Seattle, WA, USA., Proitsi P; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Boxer A; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Powell JF; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Burke JR; Department of Neurology, Duke University, Durham, NC, USA., Kauwe JSK; Departments of Biology, Brigham Young University, Provo, UT, USA., Burns JM; University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, KS, USA., Mancuso M; Department of Experimental and Clinical Medicine, Neurological Institute, University of Pisa, Pisa, Italy., Buxbaum JD; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bonuccelli U; Department of Experimental and Clinical Medicine, Neurological Institute, University of Pisa, Pisa, Italy., Cairns NJ; Department of Pathology and Immunology, Washington University, St. Louis, MO, USA., McQuillin A; Division of Psychiatry, University College London, London, UK., Cao C; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA., Livingston G; Division of Psychiatry, University College London, London, UK., Carlson CS; Department of Medicine, University of Wisconsin, Madison, WI, USA.; Wisconsin Alzheimer's Disease Research Center, Madison, WI, USA., Bass NJ; Division of Psychiatry, University College London, London, UK., Carlsson CM; Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Hardy J; Department of Molecular Neuroscience, UCL, Institute of Neurology, London, UK., Carney RM; Mental Health & Behavioral Science Service, Bruce W. Carter VA Medical Center, Miami, FL, USA., Bras J; UK Dementia Research Institute at UCL, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Carrasquillo MM; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Guerreiro R; UK Dementia Research Institute at UCL, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Allen M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Chui HC; Department of Neurology, University of Southern California, Los Angeles, CA, USA., Fisher E; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Masullo C; Department of Neurology, Catholic University of Rome, Rome, Italy., Crocco EA; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL, USA., DeCarli C; Department of Neurology, University of California, Davis, Sacramento, CA, USA., Bisceglio G; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Dick M; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA., Ma L; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Duara R; Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center, Miami Beach, FL, USA., Graff-Radford NR; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Evans DA; Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA., Hodges A; Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Faber KM; Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA., Scherer M; Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Fallon KB; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Riemenschneider M; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany., Fardo DW; Sanders-Brown Center on Aging, Department of Biostatistics, University of Kentucky, Lexington, KY, USA., Heun R; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany., Farlow MR; Department of Neurology, Indiana University, Indianapolis, IN, USA., Kölsch H; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany., Ferris S; Department of Psychiatry, New York University, New York, NY, USA., Leber M; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany., Foroud TM; Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA., Heuser I; Department of Psychiatry and Psychotherapy, Charité University Medicine, Berlin, Germany., Galasko DR; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA., Giegling I; Department of Psychiatry, Martin Luther University Halle-Wittenberg, Halle, Germany., Gearing M; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA.; Emory Alzheimer's Disease Center, Emory University, Atlanta, GA, USA., Hüll M; Department of Psychiatry, University of Freiburg, Freiburg, Germany., Geschwind DH; Neurogenetics Program, University of California, Los Angeles, Los Angeles, CA, USA., Gilbert JR; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Morris J; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, MO, USA., Green RC; Division of Genetics, Department of Medicine and Partners Center for Personalized Genetic Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Mayo K; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; Department of Neurology, Washington University, St. Louis, MO, USA.; Department of Genetics, Washington University, St. Louis, MO, USA., Growdon JH; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA., Feulner T; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany., Hamilton RL; Department of Pathology (Neuropathology), University of Pittsburgh, Pittsburgh, PA, USA., Harrell LE; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Drichel D; Cologne Center for Genomics, University of Cologne, Cologne, Germany., Honig LS; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA., Cushion TD; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Huentelman MJ; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA., Hollingworth P; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Hulette CM; Department of Pathology, Duke University, Durham, NC, USA., Hyman BT; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA., Marshall R; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Jarvik GP; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA., Meggy A; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Abner E; Sanders-Brown Center on Aging, College of Public Health, Department of Epidemiology, University of Kentucky, Lexington, KY, USA., Menzies GE; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Jin LW; Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain., Leonenko G; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Real LM; Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain., Jun GR; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA., Baldwin CT; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA., Grozeva D; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Karydas A; Swedish Medical Center, Seattle, WA, USA., Russo G; Functional Genomics Center Zurich, ETH/University of Zurich, Zurich, Switzerland., Kaye JA; Department of Neurology, Oregon Health &Science University, Portland, OR, USA.; Department of Neurology, Portland Veterans Affairs Medical Center, Portland, OR, USA., Kim R; Department of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA, USA., Jessen F; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany., Kowall NW; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Pathology, Boston University School of Medicine, Boston University, Boston, MA, USA., Vellas B; Inserm U558, University of Toulouse, Toulouse, France., Kramer JH; Department of Neuropsychology, University of California San Francisco, San Francisco, CA, USA., Vardy E; Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK., LaFerla FM; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, USA., Jöckel KH; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany., Lah JJ; Department of Neurology, Emory University, Atlanta, GA, USA., Dichgans M; Institute for Stroke and Dementia Research, Klinikum der Universität München, Munich, Germany.; German Center for Neurodegenerative Diseases, Munich, Germany., Leverenz JB; Cleveland Clinic Lou Ruvo Center for Brain Health, Cleveland Clinic, Cleveland, OH, USA., Mann D; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Levey AI; Department of Neurology, Emory University, Atlanta, GA, USA., Pickering-Brown S; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Lieberman AP; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Klopp N; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Munich, Germany., Lunetta KL; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Wichmann HE; Helmholtz Center Munich, Institute of Epidemiology, Neuherberg, Munich, Germany.; Ludwig-Maximilians University Chair of Epidemiology, Munich, Germany.; Joint Biobank Munich and KORA Biobank, Baltimore, MD, USA., Lyketsos CG; Department of Psychiatry, Johns Hopkins University, Baltimore, MD, USA., Morgan K; Human Genetics, Schools of Life Sciences and Medicine, University of Nottingham, Nottingham, UK., Marson DC; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Brown K; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK., Martiniuk F; Department of Medicine-Pulmonary, New York University, New York, NY, USA., Medway C; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK., Mash DC; Department of Neurology, University of Miami, Miami, FL, USA., Nöthen MM; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany., Masliah E; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; Department of Pathology, University of California, San Diego, La Jolla, CA, USA., Hooper NM; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., McCormick WC; Department of Medicine, University of Washington, Seattle, WA, USA., Daniele A; Institute of Neurology, Catholic University of Sacred Hearth, Rome, Italy., McCurry SM; School of Nursing Northwest Research Group on Aging, University of Washington, Seattle, WA, USA., Bayer A; Institute of Primary Care and Public Health, Cardiff University, University Hospital of Wales, Cardiff, UK., McDavid AN; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA., Gallacher J; Department of Psychiatry, University of Oxford, Oxford, UK., McKee AC; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Pathology, Boston University School of Medicine, Boston University, Boston, MA, USA., van den Bussche H; Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Mesulam M; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Brayne C; Cambridge Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK., Miller BL; Weill Institute for Neurosciences, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA., Riedel-Heller S; Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany., Miller CA; Department of Pathology, University of Southern California, Los Angeles, CA, USA., Miller JW; Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA, USA., Al-Chalabi A; Institute of Psychiatry, Psychology and Neuroscienceó, King's College London, London, UK., Morris JC; Department of Pathology and Immunology, Washington University, St. Louis, MO, USA.; Department of Neurology, Washington University, St. Louis, MO, USA., Shaw CE; Institute of Psychiatry, Psychology and Neuroscienceó, King's College London, London, UK.; UK Dementia Research Institute, King's College London, London, UK., Myers AJ; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL, USA., Wiltfang J; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.; German Center for Neurodegenerative Diseases, Goettingen, Germany.; IBiMED, Medical Sciences Department, University of Aveiro, Aveiro, Portugal., O'Bryant S; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA., Olichney JM; Department of Neurology, University of California, Davis, Sacramento, CA, USA., Alvarez V; Molecular Genetics Laboratory-Hospital, University of Central Asturias, Oviedo, Spain., Parisi JE; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Singleton AB; Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Paulson HL; Department of Neurology, University of Michigan, Ann Arbor, MI, USA.; Michigan Alzheimer Disease Center, Ann Arbor, MI, USA., Collinge J; Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK., Perry WR; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Mead S; Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK., Peskind E; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA., Cribbs DH; Department of Neurology, University of California, Irvine, Irvine, CA, USA., Rossor M; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Pierce A; Department of Neurology, University of California, Irvine, Irvine, CA, USA., Ryan NS; Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK., Poon WW; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA., Nacmias B; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.; Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy., Potter H; Department of Neurology, University of Colorado School of Medicine, Aurora, CO, USA., Sorbi S; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy., Quinn JF; Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Sacchinelli E; Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy., Raj A; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA., Spalletta G; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.; Division of Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA., Raskind M; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA., Caltagirone C; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy., Bossù P; Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy., Orfei MD; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy., Reisberg B; Department of Psychiatry, New York University, New York, NY, USA.; Alzheimer's Disease Center, New York University, New York, NY, USA., Clarke R; Oxford Healthy Aging Project, Clinical Trial Service Unit, University of Oxford, Oxford, UK., Reitz C; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.; Department of Epidemiology, Columbia University, New York, NY, USA., Smith AD; Oxford Project to Investigate Memory and Ageing, University of Oxford, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK., Ringman JM; Department of Neurology, Keck School of Medicine at the University of Southern California, Los Angeles, Los Angeles, CA, USA., Warden D; Oxford Project to Investigate Memory and Ageing, University of Oxford, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK., Roberson ED; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Wilcock G; Oxford Project to Investigate Memory and Ageing, University of Oxford, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK., Rogaeva E; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada., Bruni AC; Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy., Rosen HJ; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Gallo M; Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy., Rosenberg RN; Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Ben-Shlomo Y; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Sager MA; Department of Medicine, University of Wisconsin, Madison, WI, USA., Mecocci P; Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy., Saykin AJ; Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Neurology, Indiana University, Indianapolis, IN, USA., Pastor P; Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Terrassa, Barcelona, Spain.; Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain., Cuccaro ML; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Vance JM; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Schneider JA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.; Department of Pathology (Neuropathology), Rush University Medical Center, Chicago, IL, USA., Schneider LS; Department of Neurology, University of Southern California, Los Angeles, CA, USA.; Department of Psychiatry, University of Southern California, Los Angeles, CA, USA., Slifer S; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Seeley WW; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Smith AG; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA., Sonnen JA; Department of Pathology, University of Washington, Seattle, WA, USA., Spina S; Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN, USA., Stern RA; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Swerdlow RH; University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, KS, USA., Tang M; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Tanzi RE; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA., Trojanowski JQ; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Troncoso JC; Department of Pathology, Johns Hopkins University, Baltimore, MD, USA., Van Deerlin VM; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Van Eldik LJ; Sanders-Brown Center on Aging, Department of Neuroscience, University of Kentucky, Lexington, KY, USA., Vinters HV; Department of Neurology, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Vonsattel JP; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Pathology, Columbia University, New York, NY, USA., Weintraub S; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Welsh-Bohmer KA; Department of Neurology, Duke University, Durham, NC, USA.; Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA., Wilhelmsen KC; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Williamson J; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA., Wingo TS; Department of Neurology, Emory University, Atlanta, GA, USA.; Department of Human Genetics, Emory University, Atlanta, GA, USA., Woltjer RL; Department of Pathology, Oregon Health & Science University, Portland, OR, USA., Wright CB; National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA., Yu CE; Department of Medicine, University of Washington, Seattle, WA, USA., Yu L; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Saba Y; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Division of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria., Pilotto A; Gerontology and Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.; Department Geriatric Care, Orthogeriatrics and Rehabilitation, Galliera Hospital, Genova, Italy., Bullido MJ; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.; IdiPAZ, Instituto de Investigación Sanitaria la Paz, Madrid, Spain.; Centro de Biologia Molecular Severo Ochoa (CSIC-UAM), Madrid, Spain., Peters O; Department of Psychiatry and Psychotherapy, Charité University Medicine, Berlin, Germany.; German Center for Neurodegenerative Diseases, Berlin, Germany., Crane PK; Department of Medicine, University of Washington, Seattle, WA, USA., Bennett D; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Bosco P; Instituto di Ricovero e Cura a Carattere Scientifico, Associazione Oasi Maria Santissima Srl, Troina, Italy., Coto E; Molecular Genetics Laboratory-Hospital, University of Central Asturias, Oviedo, Spain., Boccardi V; Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy., De Jager PL; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA., Lleo A; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.; Memory Unit, Neurology Department and Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, Autonomous University Barcelona, Barcelona, Spain., Warner N; Somerset Partnership NHS Trust, Somerset, UK., Lopez OL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., Ingelsson M; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden., Deloukas P; The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Cruchaga C; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, MO, USA., Graff C; Theme Aging, Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden.; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Alzheimer Research Center, Division of Neurogeriatrics, Solna, Sweden., Gwilliam R; The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Fornage M; Brown Foundation Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, Houston, TX, USA., Goate AM; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sanchez-Juan P; Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IDIVAL), Santander, Spain., Kehoe PG; University of Bristol Medical School, Learning & Research level 2, Southmead Hospital, Bristol, UK., Amin N; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Ertekin-Taner N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Berr C; Inserm U1061 Neuropsychiatry, La Colombière Hospital, Montpellier, France.; Montpellier University, Montpellier, France., Debette S; Inserm U1127, CNRS UMR 7225, Sorbonne Universités, UPMC Université Paris 06, UMRS 1127, Institut du Cerveau et de la Moelle Épinière, Paris, France.; AP-HP, Department of Genetics, Pitié-Salpêtrière Hospital, Paris, France., Love S; University of Bristol Medical School, Learning & Research level 2, Southmead Hospital, Bristol, UK., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA., Younkin SG; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Dartigues JF; Memory Research and Resources Center, CMRR de Bordeaux, Bordeaux, France., Corcoran C; Utah State University, Logan, UT, USA., Ikram MA; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Neurology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.; Departments of Radiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Nicolas G; Normandie University, UNIROUEN, Inserm U1245, and Rouen University Hospital, Department of Neurology, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Rouen, France., Campion D; Normandie University, UNIROUEN, Inserm U1245, and Rouen University Hospital, Department of Neurology, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Rouen, France.; Department of Research Rouvray Psychiatric Hospital, Sotteville-lès-Rouen, France., Tschanz J; Utah State University, Logan, UT, USA., Schmidt H; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Division of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.; Department of Neurology, Medical University Graz, Graz, Austria., Hakonarson H; Center for Applied Genomics, Children's Hospital of Philadelphia, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Human Genetics, Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Clarimon J; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.; Memory Unit, Neurology Department and Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, Autonomous University Barcelona, Barcelona, Spain., Munger R; Utah State University, Logan, UT, USA., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz, Austria., Farrer LA; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.; Department of Ophthalmology, Boston University School of Medicine, Boston University, Boston, MA, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA., Van Broeckhoven C; Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Antwerp, Belgium.; Laboratory for Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium., C O'Donovan M; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., DeStefano AL; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Jones L; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Haines JL; Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Deleuze JF; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Owen MJ; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Mayeux R; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.; Department of Neurology, Columbia University, New York, NY, USA., Escott-Price V; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente, Washington Health Research Institute, Seattle, WA, USA., Ramirez A; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany., Wang LS; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Ruiz A; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., van Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Holmans PA; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Seshadri S; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA., Williams J; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Amouyel P; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France.; Centre Hospitalier Universitaire de Lille, Lille, France., Schellenberg GD; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Lambert JC; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France. jean-charles.lambert@pasteur-lille.fr.; Institut Pasteur de Lille, Lille, France. jean-charles.lambert@pasteur-lille.fr.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France. jean-charles.lambert@pasteur-lille.fr., Pericak-Vance MA; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA. mpericak@miami.edu. |
| Corporate Authors: | Alzheimer Disease Genetics Consortium (ADGC), European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES) |
| Source: | Nature genetics [Nat Genet] 2019 Mar; Vol. 51 (3), pp. 414-430. Date of Electronic Publication: 2019 Feb 28. |
| Publication Type: | Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 30820047 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kunkle+BW%22">Kunkle BW</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA. bkunkle@miami.edu.<br /><searchLink fieldCode="AU" term="%22Grenier-Boley+B%22">Grenier-Boley B</searchLink>; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France.<br /><searchLink fieldCode="AU" term="%22Sims+R%22">Sims R</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Bis+JC%22">Bis JC</searchLink>; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Damotte+V%22">Damotte V</searchLink>; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France.<br /><searchLink fieldCode="AU" term="%22Naj+AC%22">Naj AC</searchLink>; Department of Biostatistics and Epidemiology/Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Boland+A%22">Boland A</searchLink>; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.<br /><searchLink fieldCode="AU" term="%22Vronskaya+M%22">Vronskaya M</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22van+der+Lee+SJ%22">van der Lee SJ</searchLink>; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Amlie-Wolf+A%22">Amlie-Wolf A</searchLink>; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bellenguez+C%22">Bellenguez C</searchLink>; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France.<br /><searchLink fieldCode="AU" term="%22Frizatti+A%22">Frizatti A</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Chouraki+V%22">Chouraki V</searchLink>; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France.; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Martin+ER%22">Martin ER</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Sleegers+K%22">Sleegers K</searchLink>; Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Antwerp, Belgium.; Laboratory for Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Badarinarayan+N%22">Badarinarayan N</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Jakobsdottir+J%22">Jakobsdottir J</searchLink>; Icelandic Heart Association, Kopavogur, Iceland.<br /><searchLink fieldCode="AU" term="%22Hamilton-Nelson+KL%22">Hamilton-Nelson KL</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Moreno-Grau+S%22">Moreno-Grau S</searchLink>; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Olaso+R%22">Olaso R</searchLink>; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.<br /><searchLink fieldCode="AU" term="%22Raybould+R%22">Raybould R</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kuzma+AB%22">Kuzma AB</searchLink>; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Hiltunen+M%22">Hiltunen M</searchLink>; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Morgan+T%22">Morgan T</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Ahmad+S%22">Ahmad S</searchLink>; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Vardarajan+BN%22">Vardarajan BN</searchLink>; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.; Department of Neurology, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Epelbaum+J%22">Epelbaum J</searchLink>; UMR 894, Center for Psychiatry and Neuroscience, Inserm, Université Paris Descartes, Paris, France.<br /><searchLink fieldCode="AU" term="%22Hoffmann+P%22">Hoffmann P</searchLink>; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; Division of Medical Genetics, University Hospital and Department of Biomedicine, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Boada+M%22">Boada M</searchLink>; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Beecham+GW%22">Beecham GW</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Garnier+JG%22">Garnier JG</searchLink>; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.<br /><searchLink fieldCode="AU" term="%22Harold+D%22">Harold D</searchLink>; School of Biotechnology, Dublin City University, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Fitzpatrick+AL%22">Fitzpatrick AL</searchLink>; Department of Family Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Valladares+O%22">Valladares O</searchLink>; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Moutet+ML%22">Moutet ML</searchLink>; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.<br /><searchLink fieldCode="AU" term="%22Gerrish+A%22">Gerrish A</searchLink>; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Smith+AV%22">Smith AV</searchLink>; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Qu+L%22">Qu L</searchLink>; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bacq+D%22">Bacq D</searchLink>; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.<br /><searchLink fieldCode="AU" term="%22Denning+N%22">Denning N</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Jian+X%22">Jian X</searchLink>; Brown Foundation Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+Y%22">Zhao Y</searchLink>; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Del+Zompo+M%22">Del Zompo M</searchLink>; Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Fox+NC%22">Fox NC</searchLink>; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Choi+SH%22">Choi SH</searchLink>; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Mateo+I%22">Mateo I</searchLink>; Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IDIVAL), Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Hughes+JT%22">Hughes JT</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Adams+HH%22">Adams HH</searchLink>; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Malamon+J%22">Malamon J</searchLink>; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Sanchez-Garcia+F%22">Sanchez-Garcia F</searchLink>; Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain.<br /><searchLink fieldCode="AU" term="%22Patel+Y%22">Patel Y</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Brody+JA%22">Brody JA</searchLink>; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Dombroski+BA%22">Dombroski BA</searchLink>; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Naranjo+MCD%22">Naranjo MCD</searchLink>; Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain.<br /><searchLink fieldCode="AU" term="%22Daniilidou+M%22">Daniilidou M</searchLink>; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Eiriksdottir+G%22">Eiriksdottir G</searchLink>; Icelandic Heart Association, Kopavogur, Iceland.<br /><searchLink fieldCode="AU" term="%22Mukherjee+S%22">Mukherjee S</searchLink>; Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Wallon+D%22">Wallon D</searchLink>; Normandie University, UNIROUEN, Inserm U1245, and Rouen University Hospital, Department of Neurology, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Rouen, France.<br /><searchLink fieldCode="AU" term="%22Uphill+J%22">Uphill J</searchLink>; Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK.<br /><searchLink fieldCode="AU" term="%22Aspelund+T%22">Aspelund T</searchLink>; Icelandic Heart Association, Kopavogur, Iceland.; Centre for Public Health, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Cantwell+LB%22">Cantwell LB</searchLink>; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Garzia+F%22">Garzia F</searchLink>; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.<br /><searchLink fieldCode="AU" term="%22Galimberti+D%22">Galimberti D</searchLink>; Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Neurodegenerative Diseases Unit, Milan, Italy.; University of Milan, Centro Dino Ferrari, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Hofer+E%22">Hofer E</searchLink>; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Butkiewicz+M%22">Butkiewicz M</searchLink>; Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Fin+B%22">Fin B</searchLink>; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.<br /><searchLink fieldCode="AU" term="%22Scarpini+E%22">Scarpini E</searchLink>; Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Neurodegenerative Diseases Unit, Milan, Italy.; University of Milan, Centro Dino Ferrari, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sarnowski+C%22">Sarnowski C</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bush+WS%22">Bush WS</searchLink>; Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Meslage+S%22">Meslage S</searchLink>; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.<br /><searchLink fieldCode="AU" term="%22Kornhuber+J%22">Kornhuber J</searchLink>; Department of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22White+CC%22">White CC</searchLink>; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Song+Y%22">Song Y</searchLink>; Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Barber+RC%22">Barber RC</searchLink>; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA.<br /><searchLink fieldCode="AU" term="%22Engelborghs+S%22">Engelborghs S</searchLink>; Laboratory for Neurochemistry and Behavior, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.; Department of Neurology and Memory Clinic, Hospital Network Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Sordon+S%22">Sordon S</searchLink>; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany.<br /><searchLink fieldCode="AU" term="%22Voijnovic+D%22">Voijnovic D</searchLink>; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Adams+PM%22">Adams PM</searchLink>; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Vandenberghe+R%22">Vandenberghe R</searchLink>; Laboratory for Cognitive Neurology, Department of Neurology, University Hospital and University of Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Mayhaus+M%22">Mayhaus M</searchLink>; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany.<br /><searchLink fieldCode="AU" term="%22Cupples+LA%22">Cupples LA</searchLink>; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Albert+MS%22">Albert MS</searchLink>; Department of Neurology, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22De+Deyn+PP%22">De Deyn PP</searchLink>; Laboratory for Neurochemistry and Behavior, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.; Department of Neurology and Memory Clinic, Hospital Network Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Gu+W%22">Gu W</searchLink>; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany.<br /><searchLink fieldCode="AU" term="%22Himali+JJ%22">Himali JJ</searchLink>; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Beekly+D%22">Beekly D</searchLink>; National Alzheimer's Coordinating Center, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Squassina+A%22">Squassina A</searchLink>; Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Hartmann+AM%22">Hartmann AM</searchLink>; Department of Psychiatry, Martin Luther University Halle-Wittenberg, Halle, Germany.<br /><searchLink fieldCode="AU" term="%22Orellana+A%22">Orellana A</searchLink>; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Blacker+D%22">Blacker D</searchLink>; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Rodriguez+E%22">Rodriguez-Rodriguez E</searchLink>; Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IDIVAL), Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Lovestone+S%22">Lovestone S</searchLink>; Department of Psychiatry, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Garcia+ME%22">Garcia ME</searchLink>; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Doody+RS%22">Doody RS</searchLink>; Alzheimer's Disease and Memory Disorders Center, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Munoz-Fernadez+C%22">Munoz-Fernadez C</searchLink>; Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain.<br /><searchLink fieldCode="AU" term="%22Sussams+R%22">Sussams R</searchLink>; Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Lin+H%22">Lin H</searchLink>; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fairchild+TJ%22">Fairchild TJ</searchLink>; Office of Strategy and Measurement, University of North Texas Health Science Center, Fort Worth, TX, USA.<br /><searchLink fieldCode="AU" term="%22Benito+YA%22">Benito YA</searchLink>; Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain.<br /><searchLink fieldCode="AU" term="%22Holmes+C%22">Holmes C</searchLink>; Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Karamujić-Čomić+H%22">Karamujić-Čomić H</searchLink>; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Frosch+MP%22">Frosch MP</searchLink>; C.S. Kubik Laboratory for Neuropathology, Massachusetts General Hospital, Charlestown, MA, USA.<br /><searchLink fieldCode="AU" term="%22Thonberg+H%22">Thonberg H</searchLink>; Theme Aging, Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden.; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Alzheimer Research Center, Division of Neurogeriatrics, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Maier+W%22">Maier W</searchLink>; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Roshchupkin+G%22">Roshchupkin G</searchLink>; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ghetti+B%22">Ghetti B</searchLink>; Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Giedraitis+V%22">Giedraitis V</searchLink>; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Kawalia+A%22">Kawalia A</searchLink>; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Huebinger+RM%22">Huebinger RM</searchLink>; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kilander+L%22">Kilander L</searchLink>; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Moebus+S%22">Moebus S</searchLink>; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Hernández+I%22">Hernández I</searchLink>; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Kamboh+MI%22">Kamboh MI</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Brundin+R%22">Brundin R</searchLink>; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Turton+J%22">Turton J</searchLink>; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Yang+Q%22">Yang Q</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Katz+MJ%22">Katz MJ</searchLink>; Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA.<br /><searchLink fieldCode="AU" term="%22Concari+L%22">Concari L</searchLink>; Section of Neuroscience, DIMEC-University of Parma, Parma, Italy.; FERB-Alzheimer Center, Gazzaniga (Bergamo), Italy.<br /><searchLink fieldCode="AU" term="%22Lord+J%22">Lord J</searchLink>; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Beiser+AS%22">Beiser AS</searchLink>; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Keene+CD%22">Keene CD</searchLink>; Department of Pathology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Helisalmi+S%22">Helisalmi S</searchLink>; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Kloszewska+I%22">Kloszewska I</searchLink>; Elderly and Psychiatric Disorders Department, Medical University of Lodz, Lodz, Poland.<br /><searchLink fieldCode="AU" term="%22Kukull+WA%22">Kukull WA</searchLink>; Department of Epidemiology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Koivisto+AM%22">Koivisto AM</searchLink>; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Lynch+A%22">Lynch A</searchLink>; Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.; St. James's Hospital and Trinity College, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Tarraga+L%22">Tarraga L</searchLink>; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Larson+EB%22">Larson EB</searchLink>; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Haapasalo+A%22">Haapasalo A</searchLink>; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Lawlor+B%22">Lawlor B</searchLink>; Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.; St. James's Hospital and Trinity College, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Mosley+TH%22">Mosley TH</searchLink>; Departments of Medicine, Geriatrics, Gerontology and Neurology, University of Mississippi Medical Center, Jackson, MS, USA.<br /><searchLink fieldCode="AU" term="%22Lipton+RB%22">Lipton RB</searchLink>; Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA.<br /><searchLink fieldCode="AU" term="%22Solfrizzi+V%22">Solfrizzi V</searchLink>; Interdisciplinary Department of Medicine, Geriatric Medicine and Memory Unity, University of Bari, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Gill+M%22">Gill M</searchLink>; Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.; St. James's Hospital and Trinity College, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Longstreth+WT+Jr%22">Longstreth WT Jr</searchLink>; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Neurology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Montine+TJ%22">Montine TJ</searchLink>; Department of Pathology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Frisardi+V%22">Frisardi V</searchLink>; Department of Geriatrics, Center for Aging Brain, University of Bari, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Diez-Fairen+M%22">Diez-Fairen M</searchLink>; Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Terrassa, Barcelona, Spain.; Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rivadeneira+F%22">Rivadeneira F</searchLink>; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdamt, the Netherlands.; Netherlands Consortium on Health Aging and National Genomics Initiative, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Petersen+RC%22">Petersen RC</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Deramecourt+V%22">Deramecourt V</searchLink>; CHU Lille, Memory Center of Lille (Centre Mémoire de Ressources et de Recherche), Lille, France.<br /><searchLink fieldCode="AU" term="%22Alvarez+I%22">Alvarez I</searchLink>; Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Terrassa, Barcelona, Spain.; Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Salani+F%22">Salani F</searchLink>; Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ciaramella+A%22">Ciaramella A</searchLink>; Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Boerwinkle+E%22">Boerwinkle E</searchLink>; School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Reiman+EM%22">Reiman EM</searchLink>; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.; Arizona Alzheimer's Consortium, Phoenix, AZ, USA.; Banner Alzheimer's Institute, Phoenix, AZ, USA.; Department of Psychiatry, University of Arizona, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Fievet+N%22">Fievet N</searchLink>; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France.<br /><searchLink fieldCode="AU" term="%22Rotter+JI%22">Rotter JI</searchLink>; Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.<br /><searchLink fieldCode="AU" term="%22Reisch+JS%22">Reisch JS</searchLink>; Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Hanon+O%22">Hanon O</searchLink>; University Paris Descartes, EA 4468, AP-HP, Geriatrics Department, Hôpital Broca, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cupidi+C%22">Cupidi C</searchLink>; Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy.<br /><searchLink fieldCode="AU" term="%22Andre+Uitterlinden+AG%22">Andre Uitterlinden AG</searchLink>; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdamt, the Netherlands.; Netherlands Consortium on Health Aging and National Genomics Initiative, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Royall+DR%22">Royall DR</searchLink>; Departments of Psychiatry, Medicine, Family & Community Medicine, South Texas Veterans Health Administration Geriatric Research Education & Clinical Center (GRECC), UT Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Dufouil+C%22">Dufouil C</searchLink>; University of Bordeaux, Inserm 1219, Bordeaux, France.; Department of Neurology, Bordeaux University Hospital / CHU de Bordeaux, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Maletta+RG%22">Maletta RG</searchLink>; Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy.<br /><searchLink fieldCode="AU" term="%22de+Rojas+I%22">de Rojas I</searchLink>; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Sano+M%22">Sano M</searchLink>; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Brice+A%22">Brice A</searchLink>; Inserm U1127, CNRS UMR 7225, Sorbonne Universités, UPMC Université Paris 06, UMRS 1127, Institut du Cerveau et de la Moelle Épinière, Paris, France.; AP-HP, Department of Genetics, Pitié-Salpêtrière Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cecchetti+R%22">Cecchetti R</searchLink>; Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22George-Hyslop+PS%22">George-Hyslop PS</searchLink>; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Ritchie+K%22">Ritchie K</searchLink>; Inserm U1061 Neuropsychiatry, La Colombière Hospital, Montpellier, France.; Montpellier University, Montpellier, France.; Department of Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Tsolaki+M%22">Tsolaki M</searchLink>; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Tsuang+DW%22">Tsuang DW</searchLink>; VA Puget Sound Health Care System/>GRECC, Seattle, WA, USA.; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Dubois+B%22">Dubois B</searchLink>; Institut de la Mémoire et de la Maladie d'Alzheimer and Institut du Cerveau et de la Moelle Épinière, Département de Neurologie, Hôpital de la Pitié-Salpêtrière, Paris, France.; Institut des Neurosciences Translationnelles de Paris, Institut du Cerveau et de la Moelle Épinière, Paris, France.; Inserm, CNRS, UMR-S975, Institut du Cerveau et de la Moelle Epinière, Paris, France.; Sorbonne Universités, Université Pierre et Marie Curie, Hôpital de la Pitié-Salpêtrière, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Craig+D%22">Craig D</searchLink>; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Wu+CK%22">Wu CK</searchLink>; Departments of Neurology, Pharmacology & Neuroscience, Texas Tech University Health Science Center, Lubbock, TX, USA.<br /><searchLink fieldCode="AU" term="%22Soininen+H%22">Soininen H</searchLink>; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Avramidou+D%22">Avramidou D</searchLink>; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Albin+RL%22">Albin RL</searchLink>; Department of Neurology, University of Michigan, Ann Arbor, MI, USA.; Geriatric Research, Education and Clinical Center (GRECC), VA Ann Arbor Healthcare System (VAAAHS), Ann Arbor, MI, USA.; Michigan Alzheimer Disease Center, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Fratiglioni+L%22">Fratiglioni L</searchLink>; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Germanou+A%22">Germanou A</searchLink>; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Apostolova+LG%22">Apostolova LG</searchLink>; Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA.; Department of Neurology, Indiana University, Indianapolis, IN, USA.; Department of Radiology and Imaging Sciences, Indiana University, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Keller+L%22">Keller L</searchLink>; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Koutroumani+M%22">Koutroumani M</searchLink>; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Arnold+SE%22">Arnold SE</searchLink>; Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Panza+F%22">Panza F</searchLink>; Department of Geriatrics, Center for Aging Brain, University of Bari, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Gkatzima+O%22">Gkatzima O</searchLink>; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Asthana+S%22">Asthana S</searchLink>; Geriatric Research, Education and Clinical Center (GRECC), University of Wisconsin, Madison, WI, USA.; Department of Medicine, University of Wisconsin, Madison, WI, USA.; Wisconsin Alzheimer's Disease Research Center, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Hannequin+D%22">Hannequin D</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Whitehead+P%22">Whitehead P</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Atwood+CS%22">Atwood CS</searchLink>; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA.; Department of Neurology, Indiana University, Indianapolis, IN, USA.; Department of Radiology and Imaging Sciences, Indiana University, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Caffarra+P%22">Caffarra P</searchLink>; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, USA.; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Hampel+H%22">Hampel H</searchLink>; AXA Research Fund & Sorbonne University Chair, Paris, France.; Sorbonne University, GRC n° 21, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Paris, France.; Brain & Spine Institute, Inserm U 1127, CNRS UMR 7225, Paris, France.; Institute of Memory and Alzheimer's Disease, Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Quintela+I%22">Quintela I</searchLink>; Grupo de Medicina Xenomica, Universidade de Santiago de Compostela, Centro Nacional de Genotipado, Centro de Investigación Biomédica en Red de Enfermedades Raras, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Carracedo+Á%22">Carracedo Á</searchLink>; Grupo de Medicina Xenomica, Universidade de Santiago de Compostela, Centro Nacional de Genotipado, Centro de Investigación Biomédica en Red de Enfermedades Raras, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Lannfelt+L%22">Lannfelt L</searchLink>; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Rubinsztein+DC%22">Rubinsztein DC</searchLink>; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.; UK Dementia Research Institute, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Barnes+LL%22">Barnes LL</searchLink>; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Pasquier+F%22">Pasquier F</searchLink>; CHU Lille, Memory Center of Lille (Centre Mémoire de Ressources et de Recherche), Lille, France.<br /><searchLink fieldCode="AU" term="%22Frölich+L%22">Frölich L</searchLink>; Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Barral+S%22">Barral S</searchLink>; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.; Department of Neurology, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22McGuinness+B%22">McGuinness B</searchLink>; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Beach+TG%22">Beach TG</searchLink>; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Johnston+JA%22">Johnston JA</searchLink>; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Becker+JT%22">Becker JT</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Psychology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Passmore+P%22">Passmore P</searchLink>; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Bigio+EH%22">Bigio EH</searchLink>; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Schott+JM%22">Schott JM</searchLink>; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Bird+TD%22">Bird TD</searchLink>; Department of Neurology, University of Washington, Seattle, WA, USA.; VA Puget Sound Health Care System/>GRECC, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Warren+JD%22">Warren JD</searchLink>; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Boeve+BF%22">Boeve BF</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Lupton+MK%22">Lupton MK</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Bowen+JD%22">Bowen JD</searchLink>; Swedish Medical Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Proitsi+P%22">Proitsi P</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Boxer+A%22">Boxer A</searchLink>; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Powell+JF%22">Powell JF</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Burke+JR%22">Burke JR</searchLink>; Department of Neurology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Kauwe+JSK%22">Kauwe JSK</searchLink>; Departments of Biology, Brigham Young University, Provo, UT, USA.<br /><searchLink fieldCode="AU" term="%22Burns+JM%22">Burns JM</searchLink>; University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, KS, USA.<br /><searchLink fieldCode="AU" term="%22Mancuso+M%22">Mancuso M</searchLink>; Department of Experimental and Clinical Medicine, Neurological Institute, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Buxbaum+JD%22">Buxbaum JD</searchLink>; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bonuccelli+U%22">Bonuccelli U</searchLink>; Department of Experimental and Clinical Medicine, Neurological Institute, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Cairns+NJ%22">Cairns NJ</searchLink>; Department of Pathology and Immunology, Washington University, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22McQuillin+A%22">McQuillin A</searchLink>; Division of Psychiatry, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Cao+C%22">Cao C</searchLink>; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Livingston+G%22">Livingston G</searchLink>; Division of Psychiatry, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Carlson+CS%22">Carlson CS</searchLink>; Department of Medicine, University of Wisconsin, Madison, WI, USA.; Wisconsin Alzheimer's Disease Research Center, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Bass+NJ%22">Bass NJ</searchLink>; Division of Psychiatry, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Carlsson+CM%22">Carlsson CM</searchLink>; Fred Hutchinson Cancer Research Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Hardy+J%22">Hardy J</searchLink>; Department of Molecular Neuroscience, UCL, Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Carney+RM%22">Carney RM</searchLink>; Mental Health & Behavioral Science Service, Bruce W. Carter VA Medical Center, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Bras+J%22">Bras J</searchLink>; UK Dementia Research Institute at UCL, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Carrasquillo+MM%22">Carrasquillo MM</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Guerreiro+R%22">Guerreiro R</searchLink>; UK Dementia Research Institute at UCL, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Allen+M%22">Allen M</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Chui+HC%22">Chui HC</searchLink>; Department of Neurology, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Fisher+E%22">Fisher E</searchLink>; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Masullo+C%22">Masullo C</searchLink>; Department of Neurology, Catholic University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Crocco+EA%22">Crocco EA</searchLink>; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22DeCarli+C%22">DeCarli C</searchLink>; Department of Neurology, University of California, Davis, Sacramento, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bisceglio+G%22">Bisceglio G</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Dick+M%22">Dick M</searchLink>; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ma+L%22">Ma L</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Duara+R%22">Duara R</searchLink>; Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center, Miami Beach, FL, USA.<br /><searchLink fieldCode="AU" term="%22Graff-Radford+NR%22">Graff-Radford NR</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Evans+DA%22">Evans DA</searchLink>; Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Hodges+A%22">Hodges A</searchLink>; Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Faber+KM%22">Faber KM</searchLink>; Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Scherer+M%22">Scherer M</searchLink>; Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Fallon+KB%22">Fallon KB</searchLink>; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Riemenschneider+M%22">Riemenschneider M</searchLink>; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany.<br /><searchLink fieldCode="AU" term="%22Fardo+DW%22">Fardo DW</searchLink>; Sanders-Brown Center on Aging, Department of Biostatistics, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Heun+R%22">Heun R</searchLink>; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Farlow+MR%22">Farlow MR</searchLink>; Department of Neurology, Indiana University, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Kölsch+H%22">Kölsch H</searchLink>; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Ferris+S%22">Ferris S</searchLink>; Department of Psychiatry, New York University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Leber+M%22">Leber M</searchLink>; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Foroud+TM%22">Foroud TM</searchLink>; Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Heuser+I%22">Heuser I</searchLink>; Department of Psychiatry and Psychotherapy, Charité University Medicine, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Galasko+DR%22">Galasko DR</searchLink>; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Giegling+I%22">Giegling I</searchLink>; Department of Psychiatry, Martin Luther University Halle-Wittenberg, Halle, Germany.<br /><searchLink fieldCode="AU" term="%22Gearing+M%22">Gearing M</searchLink>; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA.; Emory Alzheimer's Disease Center, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Hüll+M%22">Hüll M</searchLink>; Department of Psychiatry, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Geschwind+DH%22">Geschwind DH</searchLink>; Neurogenetics Program, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gilbert+JR%22">Gilbert JR</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Morris+J%22">Morris J</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Green+RC%22">Green RC</searchLink>; Division of Genetics, Department of Medicine and Partners Center for Personalized Genetic Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mayo+K%22">Mayo K</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; Department of Neurology, Washington University, St. Louis, MO, USA.; Department of Genetics, Washington University, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Growdon+JH%22">Growdon JH</searchLink>; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Feulner+T%22">Feulner T</searchLink>; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany.<br /><searchLink fieldCode="AU" term="%22Hamilton+RL%22">Hamilton RL</searchLink>; Department of Pathology (Neuropathology), University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Harrell+LE%22">Harrell LE</searchLink>; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Drichel+D%22">Drichel D</searchLink>; Cologne Center for Genomics, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Honig+LS%22">Honig LS</searchLink>; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cushion+TD%22">Cushion TD</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Huentelman+MJ%22">Huentelman MJ</searchLink>; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Hollingworth+P%22">Hollingworth P</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Hulette+CM%22">Hulette CM</searchLink>; Department of Pathology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Hyman+BT%22">Hyman BT</searchLink>; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Marshall+R%22">Marshall R</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Jarvik+GP%22">Jarvik GP</searchLink>; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Meggy+A%22">Meggy A</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Abner+E%22">Abner E</searchLink>; Sanders-Brown Center on Aging, College of Public Health, Department of Epidemiology, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Menzies+GE%22">Menzies GE</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Jin+LW%22">Jin LW</searchLink>; Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Leonenko+G%22">Leonenko G</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Real+LM%22">Real LM</searchLink>; Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Jun+GR%22">Jun GR</searchLink>; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Baldwin+CT%22">Baldwin CT</searchLink>; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Grozeva+D%22">Grozeva D</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Karydas+A%22">Karydas A</searchLink>; Swedish Medical Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Russo+G%22">Russo G</searchLink>; Functional Genomics Center Zurich, ETH/University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kaye+JA%22">Kaye JA</searchLink>; Department of Neurology, Oregon Health &Science University, Portland, OR, USA.; Department of Neurology, Portland Veterans Affairs Medical Center, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Kim+R%22">Kim R</searchLink>; Department of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jessen+F%22">Jessen F</searchLink>; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Kowall+NW%22">Kowall NW</searchLink>; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Pathology, Boston University School of Medicine, Boston University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Vellas+B%22">Vellas B</searchLink>; Inserm U558, University of Toulouse, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Kramer+JH%22">Kramer JH</searchLink>; Department of Neuropsychology, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Vardy+E%22">Vardy E</searchLink>; Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22LaFerla+FM%22">LaFerla FM</searchLink>; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jöckel+KH%22">Jöckel KH</searchLink>; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Lah+JJ%22">Lah JJ</searchLink>; Department of Neurology, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Dichgans+M%22">Dichgans M</searchLink>; Institute for Stroke and Dementia Research, Klinikum der Universität München, Munich, Germany.; German Center for Neurodegenerative Diseases, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Leverenz+JB%22">Leverenz JB</searchLink>; Cleveland Clinic Lou Ruvo Center for Brain Health, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Mann+D%22">Mann D</searchLink>; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Levey+AI%22">Levey AI</searchLink>; Department of Neurology, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Pickering-Brown+S%22">Pickering-Brown S</searchLink>; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Lieberman+AP%22">Lieberman AP</searchLink>; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Klopp+N%22">Klopp N</searchLink>; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Lunetta+KL%22">Lunetta KL</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wichmann+HE%22">Wichmann HE</searchLink>; Helmholtz Center Munich, Institute of Epidemiology, Neuherberg, Munich, Germany.; Ludwig-Maximilians University Chair of Epidemiology, Munich, Germany.; Joint Biobank Munich and KORA Biobank, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lyketsos+CG%22">Lyketsos CG</searchLink>; Department of Psychiatry, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Morgan+K%22">Morgan K</searchLink>; Human Genetics, Schools of Life Sciences and Medicine, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Marson+DC%22">Marson DC</searchLink>; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Brown+K%22">Brown K</searchLink>; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Martiniuk+F%22">Martiniuk F</searchLink>; Department of Medicine-Pulmonary, New York University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Medway+C%22">Medway C</searchLink>; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Mash+DC%22">Mash DC</searchLink>; Department of Neurology, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Nöthen+MM%22">Nöthen MM</searchLink>; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Masliah+E%22">Masliah E</searchLink>; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hooper+NM%22">Hooper NM</searchLink>; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22McCormick+WC%22">McCormick WC</searchLink>; Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Daniele+A%22">Daniele A</searchLink>; Institute of Neurology, Catholic University of Sacred Hearth, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22McCurry+SM%22">McCurry SM</searchLink>; School of Nursing Northwest Research Group on Aging, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Bayer+A%22">Bayer A</searchLink>; Institute of Primary Care and Public Health, Cardiff University, University Hospital of Wales, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22McDavid+AN%22">McDavid AN</searchLink>; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Gallacher+J%22">Gallacher J</searchLink>; Department of Psychiatry, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22McKee+AC%22">McKee AC</searchLink>; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Pathology, Boston University School of Medicine, Boston University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22van+den+Bussche+H%22">van den Bussche H</searchLink>; Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Mesulam+M%22">Mesulam M</searchLink>; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Brayne+C%22">Brayne C</searchLink>; Cambridge Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Miller+BL%22">Miller BL</searchLink>; Weill Institute for Neurosciences, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Riedel-Heller+S%22">Riedel-Heller S</searchLink>; Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Miller+CA%22">Miller CA</searchLink>; Department of Pathology, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Miller+JW%22">Miller JW</searchLink>; Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA, USA.<br /><searchLink fieldCode="AU" term="%22Al-Chalabi+A%22">Al-Chalabi A</searchLink>; Institute of Psychiatry, Psychology and Neuroscienceó, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Morris+JC%22">Morris JC</searchLink>; Department of Pathology and Immunology, Washington University, St. Louis, MO, USA.; Department of Neurology, Washington University, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Shaw+CE%22">Shaw CE</searchLink>; Institute of Psychiatry, Psychology and Neuroscienceó, King's College London, London, UK.; UK Dementia Research Institute, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Myers+AJ%22">Myers AJ</searchLink>; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Wiltfang+J%22">Wiltfang J</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.; German Center for Neurodegenerative Diseases, Goettingen, Germany.; IBiMED, Medical Sciences Department, University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22O'Bryant+S%22">O'Bryant S</searchLink>; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA.<br /><searchLink fieldCode="AU" term="%22Olichney+JM%22">Olichney JM</searchLink>; Department of Neurology, University of California, Davis, Sacramento, CA, USA.<br /><searchLink fieldCode="AU" term="%22Alvarez+V%22">Alvarez V</searchLink>; Molecular Genetics Laboratory-Hospital, University of Central Asturias, Oviedo, Spain.<br /><searchLink fieldCode="AU" term="%22Parisi+JE%22">Parisi JE</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Singleton+AB%22">Singleton AB</searchLink>; Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Paulson+HL%22">Paulson HL</searchLink>; Department of Neurology, University of Michigan, Ann Arbor, MI, USA.; Michigan Alzheimer Disease Center, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Collinge+J%22">Collinge J</searchLink>; Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK.<br /><searchLink fieldCode="AU" term="%22Perry+WR%22">Perry WR</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Mead+S%22">Mead S</searchLink>; Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK.<br /><searchLink fieldCode="AU" term="%22Peskind+E%22">Peskind E</searchLink>; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Cribbs+DH%22">Cribbs DH</searchLink>; Department of Neurology, University of California, Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rossor+M%22">Rossor M</searchLink>; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Pierce+A%22">Pierce A</searchLink>; Department of Neurology, University of California, Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ryan+NS%22">Ryan NS</searchLink>; Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK.<br /><searchLink fieldCode="AU" term="%22Poon+WW%22">Poon WW</searchLink>; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nacmias+B%22">Nacmias B</searchLink>; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.; Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Potter+H%22">Potter H</searchLink>; Department of Neurology, University of Colorado School of Medicine, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Sorbi+S%22">Sorbi S</searchLink>; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Quinn+JF%22">Quinn JF</searchLink>; Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Sacchinelli+E%22">Sacchinelli E</searchLink>; Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Raj+A%22">Raj A</searchLink>; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Spalletta+G%22">Spalletta G</searchLink>; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.; Division of Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Raskind+M%22">Raskind M</searchLink>; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Caltagirone+C%22">Caltagirone C</searchLink>; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bossù+P%22">Bossù P</searchLink>; Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Orfei+MD%22">Orfei MD</searchLink>; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Reisberg+B%22">Reisberg B</searchLink>; Department of Psychiatry, New York University, New York, NY, USA.; Alzheimer's Disease Center, New York University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Clarke+R%22">Clarke R</searchLink>; Oxford Healthy Aging Project, Clinical Trial Service Unit, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Reitz+C%22">Reitz C</searchLink>; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.; Department of Epidemiology, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Smith+AD%22">Smith AD</searchLink>; Oxford Project to Investigate Memory and Ageing, University of Oxford, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Ringman+JM%22">Ringman JM</searchLink>; Department of Neurology, Keck School of Medicine at the University of Southern California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Warden+D%22">Warden D</searchLink>; Oxford Project to Investigate Memory and Ageing, University of Oxford, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Roberson+ED%22">Roberson ED</searchLink>; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Wilcock+G%22">Wilcock G</searchLink>; Oxford Project to Investigate Memory and Ageing, University of Oxford, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Rogaeva+E%22">Rogaeva E</searchLink>; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Bruni+AC%22">Bruni AC</searchLink>; Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy.<br /><searchLink fieldCode="AU" term="%22Rosen+HJ%22">Rosen HJ</searchLink>; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gallo+M%22">Gallo M</searchLink>; Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy.<br /><searchLink fieldCode="AU" term="%22Rosenberg+RN%22">Rosenberg RN</searchLink>; Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ben-Shlomo+Y%22">Ben-Shlomo Y</searchLink>; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Sager+MA%22">Sager MA</searchLink>; Department of Medicine, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Mecocci+P%22">Mecocci P</searchLink>; Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Saykin+AJ%22">Saykin AJ</searchLink>; Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Neurology, Indiana University, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Pastor+P%22">Pastor P</searchLink>; Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Terrassa, Barcelona, Spain.; Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Cuccaro+ML%22">Cuccaro ML</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Vance+JM%22">Vance JM</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Schneider+JA%22">Schneider JA</searchLink>; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.; Department of Pathology (Neuropathology), Rush University Medical Center, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Schneider+LS%22">Schneider LS</searchLink>; Department of Neurology, University of Southern California, Los Angeles, CA, USA.; Department of Psychiatry, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Slifer+S%22">Slifer S</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Seeley+WW%22">Seeley WW</searchLink>; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Smith+AG%22">Smith AG</searchLink>; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Sonnen+JA%22">Sonnen JA</searchLink>; Department of Pathology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Spina+S%22">Spina S</searchLink>; Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Stern+RA%22">Stern RA</searchLink>; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Swerdlow+RH%22">Swerdlow RH</searchLink>; University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, KS, USA.<br /><searchLink fieldCode="AU" term="%22Tang+M%22">Tang M</searchLink>; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tanzi+RE%22">Tanzi RE</searchLink>; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Trojanowski+JQ%22">Trojanowski JQ</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Troncoso+JC%22">Troncoso JC</searchLink>; Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Van+Deerlin+VM%22">Van Deerlin VM</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Van+Eldik+LJ%22">Van Eldik LJ</searchLink>; Sanders-Brown Center on Aging, Department of Neuroscience, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Vinters+HV%22">Vinters HV</searchLink>; Department of Neurology, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Vonsattel+JP%22">Vonsattel JP</searchLink>; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Pathology, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Weintraub+S%22">Weintraub S</searchLink>; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Welsh-Bohmer+KA%22">Welsh-Bohmer KA</searchLink>; Department of Neurology, Duke University, Durham, NC, USA.; Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Wilhelmsen+KC%22">Wilhelmsen KC</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Williamson+J%22">Williamson J</searchLink>; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wingo+TS%22">Wingo TS</searchLink>; Department of Neurology, Emory University, Atlanta, GA, USA.; Department of Human Genetics, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Woltjer+RL%22">Woltjer RL</searchLink>; Department of Pathology, Oregon Health & Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Wright+CB%22">Wright CB</searchLink>; National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Yu+CE%22">Yu CE</searchLink>; Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Yu+L%22">Yu L</searchLink>; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Saba+Y%22">Saba Y</searchLink>; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Division of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Pilotto+A%22">Pilotto A</searchLink>; Gerontology and Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.; Department Geriatric Care, Orthogeriatrics and Rehabilitation, Galliera Hospital, Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Bullido+MJ%22">Bullido MJ</searchLink>; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.; IdiPAZ, Instituto de Investigación Sanitaria la Paz, Madrid, Spain.; Centro de Biologia Molecular Severo Ochoa (CSIC-UAM), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Peters+O%22">Peters O</searchLink>; Department of Psychiatry and Psychotherapy, Charité University Medicine, Berlin, Germany.; German Center for Neurodegenerative Diseases, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Crane+PK%22">Crane PK</searchLink>; Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Bennett+D%22">Bennett D</searchLink>; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bosco+P%22">Bosco P</searchLink>; Instituto di Ricovero e Cura a Carattere Scientifico, Associazione Oasi Maria Santissima Srl, Troina, Italy.<br /><searchLink fieldCode="AU" term="%22Coto+E%22">Coto E</searchLink>; Molecular Genetics Laboratory-Hospital, University of Central Asturias, Oviedo, Spain.<br /><searchLink fieldCode="AU" term="%22Boccardi+V%22">Boccardi V</searchLink>; Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22De+Jager+PL%22">De Jager PL</searchLink>; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lleo+A%22">Lleo A</searchLink>; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.; Memory Unit, Neurology Department and Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, Autonomous University Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Warner+N%22">Warner N</searchLink>; Somerset Partnership NHS Trust, Somerset, UK.<br /><searchLink fieldCode="AU" term="%22Lopez+OL%22">Lopez OL</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ingelsson+M%22">Ingelsson M</searchLink>; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Deloukas+P%22">Deloukas P</searchLink>; The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Cruchaga+C%22">Cruchaga C</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Graff+C%22">Graff C</searchLink>; Theme Aging, Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden.; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Alzheimer Research Center, Division of Neurogeriatrics, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Gwilliam+R%22">Gwilliam R</searchLink>; The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Fornage+M%22">Fornage M</searchLink>; Brown Foundation Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Goate+AM%22">Goate AM</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Sanchez-Juan+P%22">Sanchez-Juan P</searchLink>; Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IDIVAL), Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Kehoe+PG%22">Kehoe PG</searchLink>; University of Bristol Medical School, Learning & Research level 2, Southmead Hospital, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Amin+N%22">Amin N</searchLink>; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ertekin-Taner+N%22">Ertekin-Taner N</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Berr+C%22">Berr C</searchLink>; Inserm U1061 Neuropsychiatry, La Colombière Hospital, Montpellier, France.; Montpellier University, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Debette+S%22">Debette S</searchLink>; Inserm U1127, CNRS UMR 7225, Sorbonne Universités, UPMC Université Paris 06, UMRS 1127, Institut du Cerveau et de la Moelle Épinière, Paris, France.; AP-HP, Department of Genetics, Pitié-Salpêtrière Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Love+S%22">Love S</searchLink>; University of Bristol Medical School, Learning & Research level 2, Southmead Hospital, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Launer+LJ%22">Launer LJ</searchLink>; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Younkin+SG%22">Younkin SG</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Dartigues+JF%22">Dartigues JF</searchLink>; Memory Research and Resources Center, CMRR de Bordeaux, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Corcoran+C%22">Corcoran C</searchLink>; Utah State University, Logan, UT, USA.<br /><searchLink fieldCode="AU" term="%22Ikram+MA%22">Ikram MA</searchLink>; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Neurology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.; Departments of Radiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Dickson+DW%22">Dickson DW</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Nicolas+G%22">Nicolas G</searchLink>; Normandie University, UNIROUEN, Inserm U1245, and Rouen University Hospital, Department of Neurology, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Rouen, France.<br /><searchLink fieldCode="AU" term="%22Campion+D%22">Campion D</searchLink>; Normandie University, UNIROUEN, Inserm U1245, and Rouen University Hospital, Department of Neurology, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Rouen, France.; Department of Research Rouvray Psychiatric Hospital, Sotteville-lès-Rouen, France.<br /><searchLink fieldCode="AU" term="%22Tschanz+J%22">Tschanz J</searchLink>; Utah State University, Logan, UT, USA.<br /><searchLink fieldCode="AU" term="%22Schmidt+H%22">Schmidt H</searchLink>; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Division of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.; Department of Neurology, Medical University Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Hakonarson+H%22">Hakonarson H</searchLink>; Center for Applied Genomics, Children's Hospital of Philadelphia, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Human Genetics, Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Clarimon+J%22">Clarimon J</searchLink>; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.; Memory Unit, Neurology Department and Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, Autonomous University Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Munger+R%22">Munger R</searchLink>; Utah State University, Logan, UT, USA.<br /><searchLink fieldCode="AU" term="%22Schmidt+R%22">Schmidt R</searchLink>; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Farrer+LA%22">Farrer LA</searchLink>; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.; Department of Ophthalmology, Boston University School of Medicine, Boston University, Boston, MA, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Van+Broeckhoven+C%22">Van Broeckhoven C</searchLink>; Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Antwerp, Belgium.; Laboratory for Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22C+O'Donovan+M%22">C O'Donovan M</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22DeStefano+AL%22">DeStefano AL</searchLink>; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jones+L%22">Jones L</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Haines+JL%22">Haines JL</searchLink>; Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Deleuze+JF%22">Deleuze JF</searchLink>; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.<br /><searchLink fieldCode="AU" term="%22Owen+MJ%22">Owen MJ</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Gudnason+V%22">Gudnason V</searchLink>; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Mayeux+R%22">Mayeux R</searchLink>; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.; Department of Neurology, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Escott-Price+V%22">Escott-Price V</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Psaty+BM%22">Psaty BM</searchLink>; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente, Washington Health Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Ramirez+A%22">Ramirez A</searchLink>; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Wang+LS%22">Wang LS</searchLink>; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ruiz+A%22">Ruiz A</searchLink>; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22van+Duijn+CM%22">van Duijn CM</searchLink>; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Holmans+PA%22">Holmans PA</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Seshadri+S%22">Seshadri S</searchLink>; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Williams+J%22">Williams J</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Amouyel+P%22">Amouyel P</searchLink>; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France.; Centre Hospitalier Universitaire de Lille, Lille, France.<br /><searchLink fieldCode="AU" term="%22Schellenberg+GD%22">Schellenberg GD</searchLink>; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Lambert+JC%22">Lambert JC</searchLink>; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France. jean-charles.lambert@pasteur-lille.fr.; Institut Pasteur de Lille, Lille, France. jean-charles.lambert@pasteur-lille.fr.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France. jean-charles.lambert@pasteur-lille.fr.<br /><searchLink fieldCode="AU" term="%22Pericak-Vance+MA%22">Pericak-Vance MA</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA. mpericak@miami.edu. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Alzheimer+Disease+Genetics+Consortium+%28ADGC%29%22">Alzheimer Disease Genetics Consortium (ADGC)</searchLink><br /><searchLink fieldCode="CA" term="%22European+Alzheimer%27s+Disease+Initiative+%28EADI%29%22">European Alzheimer’s Disease Initiative (EADI)</searchLink><br /><searchLink fieldCode="CA" term="%22Cohorts+for+Heart+and+Aging+Research+in+Genomic+Epidemiology+Consortium+%28CHARGE%29%22">Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE)</searchLink><br /><searchLink fieldCode="CA" term="%22Genetic+and+Environmental+Risk+in+AD%2FDefining+Genetic%2C+Polygenic+and+Environmental+Risk+for+Alzheimer%27s+Disease+Consortium+%28GERAD%2FPERADES%29%22">Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES)</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2019 Mar; Vol. 51 (3), pp. 414-430. <i>Date of Electronic Publication: </i>2019 Feb 28. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Co%22">Nature Pub. Co </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9216904 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1546-1718 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210614036%22">10614036 </searchLink><i>NLM ISO Abbreviation: </i>Nat Genet <i>Subsets: </i>MEDLINE |
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