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Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis.

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Title: Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis.
Authors: Morita M; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229; moritam@uthscsa.edu tadashi.yamamoto@oist.jp nahum.sonenberg@mcgill.ca.; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Institute of Resource Development and Analysis, Kumamoto University, 860-0811 Kumamoto, Japan., Siddiqui N; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada.; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada., Katsumura S; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229., Rouya C; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada.; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada., Larsson O; Department of Oncology-Pathology, Scilifelab, Karolinska Institutet, SE-171 76 Stockholm, Sweden., Nagashima T; Laboratory for Integrated Cellular Systems, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045 Kanagawa, Japan., Hekmatnejad B; Research Centre, Shriners Hospital for Children-Canada, Montreal, QC H4A 0A9, Canada.; Department of Human Genetics, McGill University, Montreal, QC H3A 2T5, Canada., Takahashi A; Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Onna-son, 904-0495 Okinawa, Japan., Kiyonari H; Laboratories for Animal Resource Development and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, 650-0047 Hyogo, Japan., Zang M; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229., St-Arnaud R; Research Centre, Shriners Hospital for Children-Canada, Montreal, QC H4A 0A9, Canada.; Department of Human Genetics, McGill University, Montreal, QC H3A 2T5, Canada., Oike Y; Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, 860-8556 Kumamoto, Japan., Giguère V; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada.; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada.; Gerald Bronfman Department of Oncology, McGill University, Montreal, QC H2W 1S6, Canada., Topisirovic I; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada.; Gerald Bronfman Department of Oncology, McGill University, Montreal, QC H2W 1S6, Canada.; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, QC H3T 1E2, Canada., Okada-Hatakeyama M; Laboratory for Integrated Cellular Systems, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045 Kanagawa, Japan.; Laboratory of Cell Systems, Institute for Protein Research, Osaka University, Suita, 565-0871 Osaka, Japan., Yamamoto T; Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Onna-son, 904-0495 Okinawa, Japan; moritam@uthscsa.edu tadashi.yamamoto@oist.jp nahum.sonenberg@mcgill.ca., Sonenberg N; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada; moritam@uthscsa.edu tadashi.yamamoto@oist.jp nahum.sonenberg@mcgill.ca.; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Apr 16; Vol. 116 (16), pp. 7973-7981. Date of Electronic Publication: 2019 Mar 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis.
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  Data: <searchLink fieldCode="AU" term="%22Morita+M%22">Morita M</searchLink>; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229; moritam@uthscsa.edu tadashi.yamamoto@oist.jp nahum.sonenberg@mcgill.ca.; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Institute of Resource Development and Analysis, Kumamoto University, 860-0811 Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Siddiqui+N%22">Siddiqui N</searchLink>; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada.; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada.<br /><searchLink fieldCode="AU" term="%22Katsumura+S%22">Katsumura S</searchLink>; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.<br /><searchLink fieldCode="AU" term="%22Rouya+C%22">Rouya C</searchLink>; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada.; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada.<br /><searchLink fieldCode="AU" term="%22Larsson+O%22">Larsson O</searchLink>; Department of Oncology-Pathology, Scilifelab, Karolinska Institutet, SE-171 76 Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Nagashima+T%22">Nagashima T</searchLink>; Laboratory for Integrated Cellular Systems, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045 Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Hekmatnejad+B%22">Hekmatnejad B</searchLink>; Research Centre, Shriners Hospital for Children-Canada, Montreal, QC H4A 0A9, Canada.; Department of Human Genetics, McGill University, Montreal, QC H3A 2T5, Canada.<br /><searchLink fieldCode="AU" term="%22Takahashi+A%22">Takahashi A</searchLink>; Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Onna-son, 904-0495 Okinawa, Japan.<br /><searchLink fieldCode="AU" term="%22Kiyonari+H%22">Kiyonari H</searchLink>; Laboratories for Animal Resource Development and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, 650-0047 Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Zang+M%22">Zang M</searchLink>; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.<br /><searchLink fieldCode="AU" term="%22St-Arnaud+R%22">St-Arnaud R</searchLink>; Research Centre, Shriners Hospital for Children-Canada, Montreal, QC H4A 0A9, Canada.; Department of Human Genetics, McGill University, Montreal, QC H3A 2T5, Canada.<br /><searchLink fieldCode="AU" term="%22Oike+Y%22">Oike Y</searchLink>; Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, 860-8556 Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Giguère+V%22">Giguère V</searchLink>; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada.; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada.; Gerald Bronfman Department of Oncology, McGill University, Montreal, QC H2W 1S6, Canada.<br /><searchLink fieldCode="AU" term="%22Topisirovic+I%22">Topisirovic I</searchLink>; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada.; Gerald Bronfman Department of Oncology, McGill University, Montreal, QC H2W 1S6, Canada.; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, QC H3T 1E2, Canada.<br /><searchLink fieldCode="AU" term="%22Okada-Hatakeyama+M%22">Okada-Hatakeyama M</searchLink>; Laboratory for Integrated Cellular Systems, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045 Kanagawa, Japan.; Laboratory of Cell Systems, Institute for Protein Research, Osaka University, Suita, 565-0871 Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+T%22">Yamamoto T</searchLink>; Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Onna-son, 904-0495 Okinawa, Japan; moritam@uthscsa.edu tadashi.yamamoto@oist.jp nahum.sonenberg@mcgill.ca.<br /><searchLink fieldCode="AU" term="%22Sonenberg+N%22">Sonenberg N</searchLink>; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada; moritam@uthscsa.edu tadashi.yamamoto@oist.jp nahum.sonenberg@mcgill.ca.; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2019 Apr 16; Vol. 116 (16), pp. 7973-7981. <i>Date of Electronic Publication: </i>2019 Mar 29.
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