Mitochondrial complex I inhibitor deguelin induces metabolic reprogramming and sensitizes vemurafenib-resistant BRAFV600E mutation bearing metastatic melanoma cells.
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| Title: | Mitochondrial complex I inhibitor deguelin induces metabolic reprogramming and sensitizes vemurafenib-resistant BRAFV600E mutation bearing metastatic melanoma cells. |
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| Authors: | Carpenter EL; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon.; Department of Dermatology, Oregon Health & Science University, Portland, Oregon., Chagani S; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon., Nelson D; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon., Cassidy PB; Department of Dermatology, Oregon Health & Science University, Portland, Oregon.; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon., Laws M; Department of Dermatology, Oregon Health & Science University, Portland, Oregon., Ganguli-Indra G; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon.; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon., Indra AK; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon.; Department of Dermatology, Oregon Health & Science University, Portland, Oregon.; Department of Biochemistry and Biophysics, OSU, Corvallis, Oregon.; Linus Pauling Institute, Oregon State University, Corvallis, Oregon.; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon. |
| Source: | Molecular carcinogenesis [Mol Carcinog] 2019 Sep; Vol. 58 (9), pp. 1680-1690. Date of Electronic Publication: 2019 Jun 18. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8811105 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2744 (Electronic) Linking ISSN: 08991987 NLM ISO Abbreviation: Mol Carcinog Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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