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Ibudilast attenuates doxorubicin-induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes.

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Title: Ibudilast attenuates doxorubicin-induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes.
Authors: Nishiyama K; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan., Numaga-Tomita T; National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences (NINS), Okazaki, Japan.; Exploratory Research Center on Life and Living Systems (ExCELLS), NINS, Okazaki, Japan.; Department of Physiological Sciences, SOKENDAI (School of Life Science, The Graduate University for Advanced Studies), Okazaki, Japan., Fujimoto Y; National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences (NINS), Okazaki, Japan.; Division of Veterinary Science, Osaka Prefecture University Graduate School of Life and Environmental Science, Osaka, Japan., Tanaka T; National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences (NINS), Okazaki, Japan.; Center for Novel Science Initiatives (CNSI), National Institutes of Natural Sciences, Tokyo, Japan., Toyama C; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan., Nishimura A; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences (NINS), Okazaki, Japan.; Exploratory Research Center on Life and Living Systems (ExCELLS), NINS, Okazaki, Japan., Yamashita T; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan., Matsunaga N; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan., Koyanagi S; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan., Azuma YT; Division of Veterinary Science, Osaka Prefecture University Graduate School of Life and Environmental Science, Osaka, Japan., Ibuki Y; Graduate Division of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka, Japan., Uchida K; Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan., Ohdo S; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan., Nishida M; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences (NINS), Okazaki, Japan.; Exploratory Research Center on Life and Living Systems (ExCELLS), NINS, Okazaki, Japan.; Department of Physiological Sciences, SOKENDAI (School of Life Science, The Graduate University for Advanced Studies), Okazaki, Japan.
Source: British journal of pharmacology [Br J Pharmacol] 2019 Sep; Vol. 176 (18), pp. 3723-3738. Date of Electronic Publication: 2019 Aug 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ibudilast attenuates doxorubicin-induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes.
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  Data: <searchLink fieldCode="AU" term="%22Nishiyama+K%22">Nishiyama K</searchLink>; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Numaga-Tomita+T%22">Numaga-Tomita T</searchLink>; National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences (NINS), Okazaki, Japan.; Exploratory Research Center on Life and Living Systems (ExCELLS), NINS, Okazaki, Japan.; Department of Physiological Sciences, SOKENDAI (School of Life Science, The Graduate University for Advanced Studies), Okazaki, Japan.<br /><searchLink fieldCode="AU" term="%22Fujimoto+Y%22">Fujimoto Y</searchLink>; National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences (NINS), Okazaki, Japan.; Division of Veterinary Science, Osaka Prefecture University Graduate School of Life and Environmental Science, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+T%22">Tanaka T</searchLink>; National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences (NINS), Okazaki, Japan.; Center for Novel Science Initiatives (CNSI), National Institutes of Natural Sciences, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Toyama+C%22">Toyama C</searchLink>; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Nishimura+A%22">Nishimura A</searchLink>; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences (NINS), Okazaki, Japan.; Exploratory Research Center on Life and Living Systems (ExCELLS), NINS, Okazaki, Japan.<br /><searchLink fieldCode="AU" term="%22Yamashita+T%22">Yamashita T</searchLink>; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Matsunaga+N%22">Matsunaga N</searchLink>; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Koyanagi+S%22">Koyanagi S</searchLink>; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Azuma+YT%22">Azuma YT</searchLink>; Division of Veterinary Science, Osaka Prefecture University Graduate School of Life and Environmental Science, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Ibuki+Y%22">Ibuki Y</searchLink>; Graduate Division of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Uchida+K%22">Uchida K</searchLink>; Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ohdo+S%22">Ohdo S</searchLink>; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Nishida+M%22">Nishida M</searchLink>; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences (NINS), Okazaki, Japan.; Exploratory Research Center on Life and Living Systems (ExCELLS), NINS, Okazaki, Japan.; Department of Physiological Sciences, SOKENDAI (School of Life Science, The Graduate University for Advanced Studies), Okazaki, Japan.
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  Data: <searchLink fieldCode="JN" term="%227502536%22">British journal of pharmacology</searchLink> [Br J Pharmacol] 2019 Sep; Vol. 176 (18), pp. 3723-3738. <i>Date of Electronic Publication: </i>2019 Aug 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7502536 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5381 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200071188%22">00071188 </searchLink><i>NLM ISO Abbreviation: </i>Br J Pharmacol <i>Subsets: </i>MEDLINE
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