View in EDS

ARAF recurrent mutation causes central conducting lymphatic anomaly treatable with a MEK inhibitor.

Saved in:
Bibliographic Details
Title: ARAF recurrent mutation causes central conducting lymphatic anomaly treatable with a MEK inhibitor.
Authors: Li D; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., March ME; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Gutierrez-Uzquiza A; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Biochemistry and Molecular Biology II, School of Pharmacy, Complutense University, Madrid, Spain., Kao C; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Seiler C; Zebrafish Core Facility, The Children's Hospital of Philadelphia Research Institute, Philadelphia, PA, USA., Pinto E; Center for Lymphatic Imaging and Interventions, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Matsuoka LS; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Battig MR; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Bhoj EJ; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Wenger TL; Division of Craniofacial Medicine, Seattle Children's Hospital, Seattle, WA, USA., Tian L; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Robinson N; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Wang T; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Liu Y; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Weinstein BM; Division of Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA., Swift M; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA., Jung HM; Division of Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA., Kaminski CN; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Chiavacci R; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Perkins JA; Division of Otolaryngology-Head and Neck Surgery, Seattle Children's Hospital, Seattle, WA, USA., Levine MA; Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sleiman PMA; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Hicks PJ; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Strausbaugh JT; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Belasco JB; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Dori Y; Center for Lymphatic Imaging and Interventions, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Hakonarson H; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. hakonarson@email.chop.edu.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. hakonarson@email.chop.edu.; Divisions of Human Genetics and Pulmonary Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. hakonarson@email.chop.edu.
Source: Nature medicine [Nat Med] 2019 Jul; Vol. 25 (7), pp. 1116-1122. Date of Electronic Publication: 2019 Jul 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 31263281
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: ARAF recurrent mutation causes central conducting lymphatic anomaly treatable with a MEK inhibitor.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22March+ME%22">March ME</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gutierrez-Uzquiza+A%22">Gutierrez-Uzquiza A</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Biochemistry and Molecular Biology II, School of Pharmacy, Complutense University, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Kao+C%22">Kao C</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Seiler+C%22">Seiler C</searchLink>; Zebrafish Core Facility, The Children's Hospital of Philadelphia Research Institute, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Pinto+E%22">Pinto E</searchLink>; Center for Lymphatic Imaging and Interventions, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Matsuoka+LS%22">Matsuoka LS</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Battig+MR%22">Battig MR</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bhoj+EJ%22">Bhoj EJ</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wenger+TL%22">Wenger TL</searchLink>; Division of Craniofacial Medicine, Seattle Children's Hospital, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Tian+L%22">Tian L</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Robinson+N%22">Robinson N</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Weinstein+BM%22">Weinstein BM</searchLink>; Division of Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Swift+M%22">Swift M</searchLink>; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA.<br /><searchLink fieldCode="AU" term="%22Jung+HM%22">Jung HM</searchLink>; Division of Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kaminski+CN%22">Kaminski CN</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Chiavacci+R%22">Chiavacci R</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Perkins+JA%22">Perkins JA</searchLink>; Division of Otolaryngology-Head and Neck Surgery, Seattle Children's Hospital, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Levine+MA%22">Levine MA</searchLink>; Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Sleiman+PMA%22">Sleiman PMA</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Hicks+PJ%22">Hicks PJ</searchLink>; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Strausbaugh+JT%22">Strausbaugh JT</searchLink>; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Belasco+JB%22">Belasco JB</searchLink>; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Dori+Y%22">Dori Y</searchLink>; Center for Lymphatic Imaging and Interventions, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Hakonarson+H%22">Hakonarson H</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. hakonarson@email.chop.edu.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. hakonarson@email.chop.edu.; Divisions of Human Genetics and Pulmonary Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. hakonarson@email.chop.edu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229502015%22">Nature medicine</searchLink> [Nat Med] 2019 Jul; Vol. 25 (7), pp. 1116-1122. <i>Date of Electronic Publication: </i>2019 Jul 01.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Company%22">Nature Publishing Company </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502015 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1546-170X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210788956%22">10788956 </searchLink><i>NLM ISO Abbreviation: </i>Nat Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=31263281
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41591-019-0479-2
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1116
    Titles:
      – TitleFull: ARAF recurrent mutation causes central conducting lymphatic anomaly treatable with a MEK inhibitor.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Li D
      – PersonEntity:
          Name:
            NameFull: March ME
      – PersonEntity:
          Name:
            NameFull: Gutierrez-Uzquiza A
      – PersonEntity:
          Name:
            NameFull: Kao C
      – PersonEntity:
          Name:
            NameFull: Seiler C
      – PersonEntity:
          Name:
            NameFull: Pinto E
      – PersonEntity:
          Name:
            NameFull: Matsuoka LS
      – PersonEntity:
          Name:
            NameFull: Battig MR
      – PersonEntity:
          Name:
            NameFull: Bhoj EJ
      – PersonEntity:
          Name:
            NameFull: Wenger TL
      – PersonEntity:
          Name:
            NameFull: Tian L
      – PersonEntity:
          Name:
            NameFull: Robinson N
      – PersonEntity:
          Name:
            NameFull: Wang T
      – PersonEntity:
          Name:
            NameFull: Liu Y
      – PersonEntity:
          Name:
            NameFull: Weinstein BM
      – PersonEntity:
          Name:
            NameFull: Swift M
      – PersonEntity:
          Name:
            NameFull: Jung HM
      – PersonEntity:
          Name:
            NameFull: Kaminski CN
      – PersonEntity:
          Name:
            NameFull: Chiavacci R
      – PersonEntity:
          Name:
            NameFull: Perkins JA
      – PersonEntity:
          Name:
            NameFull: Levine MA
      – PersonEntity:
          Name:
            NameFull: Sleiman PMA
      – PersonEntity:
          Name:
            NameFull: Hicks PJ
      – PersonEntity:
          Name:
            NameFull: Strausbaugh JT
      – PersonEntity:
          Name:
            NameFull: Belasco JB
      – PersonEntity:
          Name:
            NameFull: Dori Y
      – PersonEntity:
          Name:
            NameFull: Hakonarson H
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: 2019 Jul
              Type: published
              Y: 2019
          Identifiers:
            – Type: issn-electronic
              Value: 1546-170X
          Numbering:
            – Type: volume
              Value: 25
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Nature medicine
              Type: main
ResultId 1