Electroporation of a nanoparticle-associated DNA vaccine induces higher inflammation and immunity compared to its delivery with microneedle patches in pigs.

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Title: Electroporation of a nanoparticle-associated DNA vaccine induces higher inflammation and immunity compared to its delivery with microneedle patches in pigs.
Authors: Bernelin-Cottet C; VIM, INRA, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France., Urien C; VIM, INRA, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France., McCaffrey J; School of Pharmacy, School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland; Xeolas Pharmaceuticals Ltd., Dublin, Ireland., Collins D; School of Pharmacy, School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland; Xeolas Pharmaceuticals Ltd., Dublin, Ireland., Donadei A; School of Pharmacy, School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland; Xeolas Pharmaceuticals Ltd., Dublin, Ireland., McDaid D; Xeolas Pharmaceuticals Ltd., Dublin, Ireland., Jakob V; Vaccine Formulation Laboratory, University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland., Barnier-Quer C; Vaccine Formulation Laboratory, University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland., Collin N; Vaccine Formulation Laboratory, University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland., Bouguyon E; VIM, INRA, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France., Bordet E; VIM, INRA, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France., Barc C; PFIE-UE1277, INRA, 37380 Nouzilly, France., Boulesteix O; PFIE-UE1277, INRA, 37380 Nouzilly, France., Leplat JJ; GABI, INRA-AgroParisTech, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France., Blanc F; GABI, INRA-AgroParisTech, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France., Contreras V; Immunology of viral infections and autoimmune diseases, IDMIT Department, IBFJ, INSERM U1184-CEA - Université Paris Sud 11, Fontenay-Aux-Roses et Le Kremlin-Bicêtre, France., Bertho N; VIM, INRA, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France; BIOEPAR, Oniris, INRA, 44307 Nantes, France., Moore AC; School of Pharmacy, School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland., Schwartz-Cornil I; VIM, INRA, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France. Electronic address: isabelle.schwartz@inra.fr.
Source: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2019 Aug 28; Vol. 308, pp. 14-28. Date of Electronic Publication: 2019 Jun 29.
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Electroporation of a nanoparticle-associated DNA vaccine induces higher inflammation and immunity compared to its delivery with microneedle patches in pigs.
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  Data: <searchLink fieldCode="AU" term="%22Bernelin-Cottet+C%22">Bernelin-Cottet C</searchLink>; VIM, INRA, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France.<br /><searchLink fieldCode="AU" term="%22Urien+C%22">Urien C</searchLink>; VIM, INRA, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France.<br /><searchLink fieldCode="AU" term="%22McCaffrey+J%22">McCaffrey J</searchLink>; School of Pharmacy, School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland; Xeolas Pharmaceuticals Ltd., Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Collins+D%22">Collins D</searchLink>; School of Pharmacy, School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland; Xeolas Pharmaceuticals Ltd., Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Donadei+A%22">Donadei A</searchLink>; School of Pharmacy, School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland; Xeolas Pharmaceuticals Ltd., Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22McDaid+D%22">McDaid D</searchLink>; Xeolas Pharmaceuticals Ltd., Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Jakob+V%22">Jakob V</searchLink>; Vaccine Formulation Laboratory, University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland.<br /><searchLink fieldCode="AU" term="%22Barnier-Quer+C%22">Barnier-Quer C</searchLink>; Vaccine Formulation Laboratory, University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland.<br /><searchLink fieldCode="AU" term="%22Collin+N%22">Collin N</searchLink>; Vaccine Formulation Laboratory, University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bouguyon+E%22">Bouguyon E</searchLink>; VIM, INRA, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France.<br /><searchLink fieldCode="AU" term="%22Bordet+E%22">Bordet E</searchLink>; VIM, INRA, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France.<br /><searchLink fieldCode="AU" term="%22Barc+C%22">Barc C</searchLink>; PFIE-UE1277, INRA, 37380 Nouzilly, France.<br /><searchLink fieldCode="AU" term="%22Boulesteix+O%22">Boulesteix O</searchLink>; PFIE-UE1277, INRA, 37380 Nouzilly, France.<br /><searchLink fieldCode="AU" term="%22Leplat+JJ%22">Leplat JJ</searchLink>; GABI, INRA-AgroParisTech, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France.<br /><searchLink fieldCode="AU" term="%22Blanc+F%22">Blanc F</searchLink>; GABI, INRA-AgroParisTech, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France.<br /><searchLink fieldCode="AU" term="%22Contreras+V%22">Contreras V</searchLink>; Immunology of viral infections and autoimmune diseases, IDMIT Department, IBFJ, INSERM U1184-CEA - Université Paris Sud 11, Fontenay-Aux-Roses et Le Kremlin-Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Bertho+N%22">Bertho N</searchLink>; VIM, INRA, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France; BIOEPAR, Oniris, INRA, 44307 Nantes, France.<br /><searchLink fieldCode="AU" term="%22Moore+AC%22">Moore AC</searchLink>; School of Pharmacy, School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Schwartz-Cornil+I%22">Schwartz-Cornil I</searchLink>; VIM, INRA, Université Paris-Saclay, Domaine de Vilvert, 78350 Jouy-en-Josas, France. Electronic address: isabelle.schwartz@inra.fr.
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  Data: <searchLink fieldCode="JN" term="%228607908%22">Journal of controlled release : official journal of the Controlled Release Society</searchLink> [J Control Release] 2019 Aug 28; Vol. 308, pp. 14-28. <i>Date of Electronic Publication: </i>2019 Jun 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Publishers%22">Elsevier Science Publishers </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8607908 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4995 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201683659%22">01683659 </searchLink><i>NLM ISO Abbreviation: </i>J Control Release <i>Subsets: </i>MEDLINE
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