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Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad.

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Title: Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad.
Authors: Kumar P; Graduate School of Genome Science and Technology, University of Tennessee, Knoxville, TN, 37996, USA.; Present address: Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Agarwal PK; Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN, 37996, USA., Waddell MB; Molecular Interaction Analysis Shared Resource, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Mittag T; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Serpersu EH; Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN, 37996, USA.; National Science Foundation, Alexandria, VA, 22314, USA., Cuneo MJ; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.; Oak Ridge National Laboratory, Oak Ridge, TN, 37830, USA.
Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2019 Nov 04; Vol. 58 (45), pp. 16260-16266. Date of Electronic Publication: 2019 Sep 24.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kumar+P%22">Kumar P</searchLink>; Graduate School of Genome Science and Technology, University of Tennessee, Knoxville, TN, 37996, USA.; Present address: Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Agarwal+PK%22">Agarwal PK</searchLink>; Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN, 37996, USA.<br /><searchLink fieldCode="AU" term="%22Waddell+MB%22">Waddell MB</searchLink>; Molecular Interaction Analysis Shared Resource, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.<br /><searchLink fieldCode="AU" term="%22Mittag+T%22">Mittag T</searchLink>; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.<br /><searchLink fieldCode="AU" term="%22Serpersu+EH%22">Serpersu EH</searchLink>; Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN, 37996, USA.; National Science Foundation, Alexandria, VA, 22314, USA.<br /><searchLink fieldCode="AU" term="%22Cuneo+MJ%22">Cuneo MJ</searchLink>; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.; Oak Ridge National Laboratory, Oak Ridge, TN, 37830, USA.
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