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Modulation of tumor microenvironment using a TLR-7/8 agonist-loaded nanoparticle system that exerts low-temperature hyperthermia and immunotherapy for in situ cancer vaccination.

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Title: Modulation of tumor microenvironment using a TLR-7/8 agonist-loaded nanoparticle system that exerts low-temperature hyperthermia and immunotherapy for in situ cancer vaccination.
Authors: Chen PM; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC., Pan WY; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC., Wu CY; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC., Yeh CY; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC., Korupalli C; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC., Luo PK; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC., Chou CJ; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC., Chia WT; Department of Orthopedics, National Taiwan University Hospital, Hsinchu Branch, Hsinchu, Taiwan, ROC. Electronic address: H56009@hch.gov.tw., Sung HW; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC. Electronic address: hwsung@mx.nthu.edu.tw.
Source: Biomaterials [Biomaterials] 2020 Feb; Vol. 230, pp. 119629. Date of Electronic Publication: 2019 Nov 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8100316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5905 (Electronic) Linking ISSN: 01429612 NLM ISO Abbreviation: Biomaterials Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Modulation of tumor microenvironment using a TLR-7/8 agonist-loaded nanoparticle system that exerts low-temperature hyperthermia and immunotherapy for in situ cancer vaccination.
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  Data: <searchLink fieldCode="AU" term="%22Chen+PM%22">Chen PM</searchLink>; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Pan+WY%22">Pan WY</searchLink>; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Wu+CY%22">Wu CY</searchLink>; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Yeh+CY%22">Yeh CY</searchLink>; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Korupalli+C%22">Korupalli C</searchLink>; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Luo+PK%22">Luo PK</searchLink>; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chou+CJ%22">Chou CJ</searchLink>; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chia+WT%22">Chia WT</searchLink>; Department of Orthopedics, National Taiwan University Hospital, Hsinchu Branch, Hsinchu, Taiwan, ROC. Electronic address: H56009@hch.gov.tw.<br /><searchLink fieldCode="AU" term="%22Sung+HW%22">Sung HW</searchLink>; Department of Chemical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC. Electronic address: hwsung@mx.nthu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%228100316%22">Biomaterials</searchLink> [Biomaterials] 2020 Feb; Vol. 230, pp. 119629. <i>Date of Electronic Publication: </i>2019 Nov 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8100316 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-5905 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201429612%22">01429612 </searchLink><i>NLM ISO Abbreviation: </i>Biomaterials <i>Subsets: </i>MEDLINE
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              Text: 2020 Feb
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