CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci.

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Title: CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci.
Authors: Chylinski K; Vienna Biocenter Core Facilities, Vienna Biocenter (VBC), Dr. Bohr Gasse 3, Vienna, Austria., Hubmann M; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna Biocenter (VBC), Dr. Bohr Gasse 3, 1030, Vienna, Austria., Hanna RE; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Yanchus C; Centre for Molecular and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Michlits G; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna Biocenter (VBC), Dr. Bohr Gasse 3, 1030, Vienna, Austria., Uijttewaal ECH; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna Biocenter (VBC), Dr. Bohr Gasse 3, 1030, Vienna, Austria., Doench J; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Schramek D; Centre for Molecular and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Elling U; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna Biocenter (VBC), Dr. Bohr Gasse 3, 1030, Vienna, Austria. ulrich.elling@imba.oeaw.ac.at.
Source: Nature communications [Nat Commun] 2019 Nov 29; Vol. 10 (1), pp. 5454. Date of Electronic Publication: 2019 Nov 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci.
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  Data: <searchLink fieldCode="AU" term="%22Chylinski+K%22">Chylinski K</searchLink>; Vienna Biocenter Core Facilities, Vienna Biocenter (VBC), Dr. Bohr Gasse 3, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hubmann+M%22">Hubmann M</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna Biocenter (VBC), Dr. Bohr Gasse 3, 1030, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hanna+RE%22">Hanna RE</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yanchus+C%22">Yanchus C</searchLink>; Centre for Molecular and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Michlits+G%22">Michlits G</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna Biocenter (VBC), Dr. Bohr Gasse 3, 1030, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Uijttewaal+ECH%22">Uijttewaal ECH</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna Biocenter (VBC), Dr. Bohr Gasse 3, 1030, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Doench+J%22">Doench J</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Schramek+D%22">Schramek D</searchLink>; Centre for Molecular and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Elling+U%22">Elling U</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna Biocenter (VBC), Dr. Bohr Gasse 3, 1030, Vienna, Austria. ulrich.elling@imba.oeaw.ac.at.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2019 Nov 29; Vol. 10 (1), pp. 5454. <i>Date of Electronic Publication: </i>2019 Nov 29.
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