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Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia.

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Title: Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia.
Authors: Pei S; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Pollyea DA; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Gustafson A; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Stevens BM; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Minhajuddin M; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Fu R; RNA Bioscience Initiative, University of Colorado School of Medicine, Aurora, Colorado., Riemondy KA; RNA Bioscience Initiative, University of Colorado School of Medicine, Aurora, Colorado., Gillen AE; RNA Bioscience Initiative, University of Colorado School of Medicine, Aurora, Colorado., Sheridan RM; RNA Bioscience Initiative, University of Colorado School of Medicine, Aurora, Colorado., Kim J; Division of Medical Oncology, University of Colorado School of Medicine, Aurora, Colorado., Costello JC; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Amaya ML; Division of Medical Oncology, University of Colorado School of Medicine, Aurora, Colorado., Inguva A; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Winters A; Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado., Ye H; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Krug A; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Jones CL; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Adane B; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Khan N; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Ponder J; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Schowinsky J; Department of Pathology, University of Colorado School of Medicine, Aurora, Colorado., Abbott D; Center for Innovative Design and Analysis, Colorado School of Public Health, Aurora, Colorado., Hammes A; Center for Innovative Design and Analysis, Colorado School of Public Health, Aurora, Colorado., Myers JR; Genomics Research Center, University of Rochester, Rochester, New York., Ashton JM; Genomics Research Center, University of Rochester, Rochester, New York., Nemkov T; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, Colorado., D'Alessandro A; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, Colorado., Gutman JA; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Ramsey HE; Department of Internal Medicine, Vanderbilt University School of Medicine, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee., Savona MR; Department of Internal Medicine, Vanderbilt University School of Medicine, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee., Smith CA; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado., Jordan CT; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado. craig.jordan@cuanschutz.edu.
Source: Cancer discovery [Cancer Discov] 2020 Apr; Vol. 10 (4), pp. 536-551. Date of Electronic Publication: 2020 Jan 23.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
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  Data: Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Pei+S%22">Pei S</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Pollyea+DA%22">Pollyea DA</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Gustafson+A%22">Gustafson A</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Stevens+BM%22">Stevens BM</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Minhajuddin+M%22">Minhajuddin M</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Fu+R%22">Fu R</searchLink>; RNA Bioscience Initiative, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Riemondy+KA%22">Riemondy KA</searchLink>; RNA Bioscience Initiative, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Gillen+AE%22">Gillen AE</searchLink>; RNA Bioscience Initiative, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Sheridan+RM%22">Sheridan RM</searchLink>; RNA Bioscience Initiative, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Division of Medical Oncology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Costello+JC%22">Costello JC</searchLink>; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Amaya+ML%22">Amaya ML</searchLink>; Division of Medical Oncology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Inguva+A%22">Inguva A</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Winters+A%22">Winters A</searchLink>; Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Ye+H%22">Ye H</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Krug+A%22">Krug A</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Jones+CL%22">Jones CL</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Adane+B%22">Adane B</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Khan+N%22">Khan N</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Ponder+J%22">Ponder J</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Schowinsky+J%22">Schowinsky J</searchLink>; Department of Pathology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Abbott+D%22">Abbott D</searchLink>; Center for Innovative Design and Analysis, Colorado School of Public Health, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Hammes+A%22">Hammes A</searchLink>; Center for Innovative Design and Analysis, Colorado School of Public Health, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Myers+JR%22">Myers JR</searchLink>; Genomics Research Center, University of Rochester, Rochester, New York.<br /><searchLink fieldCode="AU" term="%22Ashton+JM%22">Ashton JM</searchLink>; Genomics Research Center, University of Rochester, Rochester, New York.<br /><searchLink fieldCode="AU" term="%22Nemkov+T%22">Nemkov T</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22D'Alessandro+A%22">D'Alessandro A</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Gutman+JA%22">Gutman JA</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Ramsey+HE%22">Ramsey HE</searchLink>; Department of Internal Medicine, Vanderbilt University School of Medicine, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Savona+MR%22">Savona MR</searchLink>; Department of Internal Medicine, Vanderbilt University School of Medicine, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Smith+CA%22">Smith CA</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Jordan+CT%22">Jordan CT</searchLink>; Division of Hematology, University of Colorado School of Medicine, Aurora, Colorado. craig.jordan@cuanschutz.edu.
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  Data: <searchLink fieldCode="JN" term="%22101561693%22">Cancer discovery</searchLink> [Cancer Discov] 2020 Apr; Vol. 10 (4), pp. 536-551. <i>Date of Electronic Publication: </i>2020 Jan 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101561693 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2159-8290 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221598274%22">21598274 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Discov <i>Subsets: </i>MEDLINE
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