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Endothelial dysfunction is an early indicator of sepsis and neutrophil degranulation of septic shock in surgical patients.

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Title: Endothelial dysfunction is an early indicator of sepsis and neutrophil degranulation of septic shock in surgical patients.
Authors: Martin-Fernandez M; Group for Biomedical Research in Sepsis (BioSepsis), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.; Research Unit, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Vaquero-Roncero LM; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain., Almansa R; Group for Biomedical Research in Sepsis (BioSepsis), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.; Research Unit, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.; Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Instituto de Salud Carlos III, Madrid, Spain., Gómez-Sánchez E; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Martín S; Anaesthesiology and Reanimation Service, Hospital Universitario Río Hortega, Valladolid, Spain., Tamayo E; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Esteban-Velasco MC; Department of General and Gastrointestinal Surgery, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL) and Universidad de Salamanca, Salamanca, Spain., Ruiz-Granado P; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Aragón M; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Calvo D; Clinical Analysis Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Rico-Feijoo J; Anaesthesiology and Reanimation Service, Hospital Universitario Río Hortega, Valladolid, Spain., Ortega A; Group for Biomedical Research in Sepsis (BioSepsis), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.; Research Unit, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Gómez-Pesquera E; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Lorenzo-López M; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., López J; Department of General and Gastrointestinal Surgery, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL) and Universidad de Salamanca, Salamanca, Spain., Doncel C; Group for Biomedical Research in Sepsis (BioSepsis), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.; Research Unit, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., González-Sanchez C; Department of General and Gastrointestinal Surgery, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL) and Universidad de Salamanca, Salamanca, Spain., Álvarez D; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain., Zarca E; Clinical Analysis Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Ríos-Llorente A; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain., Diaz-Alvarez A; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain., Sanchez-Barrado E; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain., Andaluz-Ojeda D; Intensive Care Medicine Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Calvo-Vecino JM; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain., Muñoz-Bellvís L; Department of General and Gastrointestinal Surgery, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL) and Universidad de Salamanca, Salamanca, Spain.; Biomedical Research Networking Centre on Cancer (CIBERONC), Madrid, Spain., Gomez-Herreras JI; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Abad-Molina C; Microbiology and Immunology Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Bermejo-Martin JF; Group for Biomedical Research in Sepsis (BioSepsis), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.; Research Unit, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.; Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Instituto de Salud Carlos III, Madrid, Spain., Aldecoa C; Anaesthesiology and Reanimation Service, Hospital Universitario Río Hortega, Valladolid, Spain., Heredia-Rodríguez M; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain.
Source: BJS open [BJS Open] 2020 Jun; Vol. 4 (3), pp. 524-534. Date of Electronic Publication: 2020 Feb 19.
Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101722685 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2474-9842 (Electronic) Linking ISSN: 24749842 NLM ISO Abbreviation: BJS Open Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: Endothelial dysfunction is an early indicator of sepsis and neutrophil degranulation of septic shock in surgical patients.
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  Data: <searchLink fieldCode="AU" term="%22Martin-Fernandez+M%22">Martin-Fernandez M</searchLink>; Group for Biomedical Research in Sepsis (BioSepsis), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.; Research Unit, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Vaquero-Roncero+LM%22">Vaquero-Roncero LM</searchLink>; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Almansa+R%22">Almansa R</searchLink>; Group for Biomedical Research in Sepsis (BioSepsis), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.; Research Unit, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.; Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gómez-Sánchez+E%22">Gómez-Sánchez E</searchLink>; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Martín+S%22">Martín S</searchLink>; Anaesthesiology and Reanimation Service, Hospital Universitario Río Hortega, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Tamayo+E%22">Tamayo E</searchLink>; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Esteban-Velasco+MC%22">Esteban-Velasco MC</searchLink>; Department of General and Gastrointestinal Surgery, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL) and Universidad de Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Ruiz-Granado+P%22">Ruiz-Granado P</searchLink>; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Aragón+M%22">Aragón M</searchLink>; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Calvo+D%22">Calvo D</searchLink>; Clinical Analysis Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Rico-Feijoo+J%22">Rico-Feijoo J</searchLink>; Anaesthesiology and Reanimation Service, Hospital Universitario Río Hortega, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Ortega+A%22">Ortega A</searchLink>; Group for Biomedical Research in Sepsis (BioSepsis), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.; Research Unit, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Gómez-Pesquera+E%22">Gómez-Pesquera E</searchLink>; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Lorenzo-López+M%22">Lorenzo-López M</searchLink>; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22López+J%22">López J</searchLink>; Department of General and Gastrointestinal Surgery, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL) and Universidad de Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Doncel+C%22">Doncel C</searchLink>; Group for Biomedical Research in Sepsis (BioSepsis), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.; Research Unit, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22González-Sanchez+C%22">González-Sanchez C</searchLink>; Department of General and Gastrointestinal Surgery, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL) and Universidad de Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Álvarez+D%22">Álvarez D</searchLink>; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Zarca+E%22">Zarca E</searchLink>; Clinical Analysis Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Ríos-Llorente+A%22">Ríos-Llorente A</searchLink>; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Diaz-Alvarez+A%22">Diaz-Alvarez A</searchLink>; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Sanchez-Barrado+E%22">Sanchez-Barrado E</searchLink>; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Andaluz-Ojeda+D%22">Andaluz-Ojeda D</searchLink>; Intensive Care Medicine Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Calvo-Vecino+JM%22">Calvo-Vecino JM</searchLink>; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Muñoz-Bellvís+L%22">Muñoz-Bellvís L</searchLink>; Department of General and Gastrointestinal Surgery, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL) and Universidad de Salamanca, Salamanca, Spain.; Biomedical Research Networking Centre on Cancer (CIBERONC), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gomez-Herreras+JI%22">Gomez-Herreras JI</searchLink>; Group for Biomedical Research in Critical Care (BioCritic), Anaesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Abad-Molina+C%22">Abad-Molina C</searchLink>; Microbiology and Immunology Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Bermejo-Martin+JF%22">Bermejo-Martin JF</searchLink>; Group for Biomedical Research in Sepsis (BioSepsis), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.; Research Unit, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.; Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Aldecoa+C%22">Aldecoa C</searchLink>; Anaesthesiology and Reanimation Service, Hospital Universitario Río Hortega, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Heredia-Rodríguez+M%22">Heredia-Rodríguez M</searchLink>; Anaesthesiology and Reanimation Service, Hospital Universitario de Salamanca, Salamanca, Spain.
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  Data: <searchLink fieldCode="JN" term="%22101722685%22">BJS open</searchLink> [BJS Open] 2020 Jun; Vol. 4 (3), pp. 524-534. <i>Date of Electronic Publication: </i>2020 Feb 19.
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