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Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus.

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Title: Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus.
Authors: Ferguson MS; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Chard Dunmall LS; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Gangeswaran R; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Marelli G; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Tysome JR; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; Otolaryngology Department, Cambridge University Hospitals, Cambridge, UK., Burns E; Centre for Cell Signalling, Barts Cancer Institute, Queen Mary University of London, London, UK., Whitehead MA; UCL Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC1E 6BT, UK., Aksoy E; William Harvey Research Institute, Queen Mary University of London, London, UK., Alusi G; Department of Otolaryngology, Head & Neck Surgery, Barts Health NHS Trust, The Royal London Hospital, Whitechapel Road, Whitechapel, London E1 1BB, UK., Hiley C; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Ahmed J; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Vanhaesebroeck B; UCL Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC1E 6BT, UK., Lemoine NR; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; National Centre for International Research in Cell and Gene Therapy, Sino-British Research Centre for Molecular Oncology, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China., Wang Y; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; National Centre for International Research in Cell and Gene Therapy, Sino-British Research Centre for Molecular Oncology, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China. Electronic address: yaohe.wang@qmul.ac.uk.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2020 May 06; Vol. 28 (5), pp. 1263-1275. Date of Electronic Publication: 2020 Feb 28.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus.
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  Data: <searchLink fieldCode="AU" term="%22Ferguson+MS%22">Ferguson MS</searchLink>; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Chard+Dunmall+LS%22">Chard Dunmall LS</searchLink>; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Gangeswaran+R%22">Gangeswaran R</searchLink>; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Marelli+G%22">Marelli G</searchLink>; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Tysome+JR%22">Tysome JR</searchLink>; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; Otolaryngology Department, Cambridge University Hospitals, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Burns+E%22">Burns E</searchLink>; Centre for Cell Signalling, Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Whitehead+MA%22">Whitehead MA</searchLink>; UCL Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Aksoy+E%22">Aksoy E</searchLink>; William Harvey Research Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Alusi+G%22">Alusi G</searchLink>; Department of Otolaryngology, Head & Neck Surgery, Barts Health NHS Trust, The Royal London Hospital, Whitechapel Road, Whitechapel, London E1 1BB, UK.<br /><searchLink fieldCode="AU" term="%22Hiley+C%22">Hiley C</searchLink>; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ahmed+J%22">Ahmed J</searchLink>; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Vanhaesebroeck+B%22">Vanhaesebroeck B</searchLink>; UCL Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Lemoine+NR%22">Lemoine NR</searchLink>; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; National Centre for International Research in Cell and Gene Therapy, Sino-British Research Centre for Molecular Oncology, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; National Centre for International Research in Cell and Gene Therapy, Sino-British Research Centre for Molecular Oncology, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China. Electronic address: yaohe.wang@qmul.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22100890581%22">Molecular therapy : the journal of the American Society of Gene Therapy</searchLink> [Mol Ther] 2020 May 06; Vol. 28 (5), pp. 1263-1275. <i>Date of Electronic Publication: </i>2020 Feb 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100890581 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-0024 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215250016%22">15250016 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther <i>Subsets: </i>MEDLINE
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