Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus.
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| Title: | Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus. |
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| Authors: | Ferguson MS; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Chard Dunmall LS; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Gangeswaran R; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Marelli G; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Tysome JR; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; Otolaryngology Department, Cambridge University Hospitals, Cambridge, UK., Burns E; Centre for Cell Signalling, Barts Cancer Institute, Queen Mary University of London, London, UK., Whitehead MA; UCL Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC1E 6BT, UK., Aksoy E; William Harvey Research Institute, Queen Mary University of London, London, UK., Alusi G; Department of Otolaryngology, Head & Neck Surgery, Barts Health NHS Trust, The Royal London Hospital, Whitechapel Road, Whitechapel, London E1 1BB, UK., Hiley C; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Ahmed J; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Vanhaesebroeck B; UCL Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC1E 6BT, UK., Lemoine NR; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; National Centre for International Research in Cell and Gene Therapy, Sino-British Research Centre for Molecular Oncology, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China., Wang Y; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; National Centre for International Research in Cell and Gene Therapy, Sino-British Research Centre for Molecular Oncology, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China. Electronic address: yaohe.wang@qmul.ac.uk. |
| Source: | Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2020 May 06; Vol. 28 (5), pp. 1263-1275. Date of Electronic Publication: 2020 Feb 28. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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