Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen.

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Title: Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen.
Authors: Vardhana SA; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA., Hwee MA; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Berisa M; The Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wells DK; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA., Yost KE; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA., King B; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Smith M; Department of Medicine and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Herrera PS; Department of Medicine and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medical College, New York, NY, USA., Chang HY; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA.; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA., Satpathy AT; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., van den Brink MRM; Department of Medicine and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cross JR; The Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Thompson CB; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. thompsonc@mskcc.org.; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA. thompsonc@mskcc.org.
Source: Nature immunology [Nat Immunol] 2020 Sep; Vol. 21 (9), pp. 1022-1033. Date of Electronic Publication: 2020 Jul 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Vardhana+SA%22">Vardhana SA</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hwee+MA%22">Hwee MA</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Berisa+M%22">Berisa M</searchLink>; The Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wells+DK%22">Wells DK</searchLink>; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yost+KE%22">Yost KE</searchLink>; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22King+B%22">King B</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Smith+M%22">Smith M</searchLink>; Department of Medicine and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Herrera+PS%22">Herrera PS</searchLink>; Department of Medicine and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chang+HY%22">Chang HY</searchLink>; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA.; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Satpathy+AT%22">Satpathy AT</searchLink>; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22van+den+Brink+MRM%22">van den Brink MRM</searchLink>; Department of Medicine and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cross+JR%22">Cross JR</searchLink>; The Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Thompson+CB%22">Thompson CB</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. thompsonc@mskcc.org.; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA. thompsonc@mskcc.org.
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  Data: <searchLink fieldCode="JN" term="%22100941354%22">Nature immunology</searchLink> [Nat Immunol] 2020 Sep; Vol. 21 (9), pp. 1022-1033. <i>Date of Electronic Publication: </i>2020 Jul 13.
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