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Dual targeting of hepatic fibrosis and atherogenesis by icosabutate, an engineered eicosapentaenoic acid derivative.

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Title: Dual targeting of hepatic fibrosis and atherogenesis by icosabutate, an engineered eicosapentaenoic acid derivative.
Authors: Stokman G; TNO Metabolic Health Research, Leiden, The Netherlands., van den Hoek AM; TNO Metabolic Health Research, Leiden, The Netherlands., Denker Thorbekk D; Gubra, Hørsholm, Denmark., Pieterman EJ; TNO Metabolic Health Research, Leiden, The Netherlands., Skovgård Veidal S; Gubra, Hørsholm, Denmark., Basta B; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Iruarrizaga-Lejarreta M; OWL Metabolomics, Parque Tecnológico de Bizkaia, Zamudio, Spain., van der Hoorn JW; TNO Metabolic Health Research, Leiden, The Netherlands., Verschuren L; TNO Microbiology & Systems Biology, Zeist, The Netherlands., Berbée JFP; Department. of Medicine, Division of Endocrinology, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Rensen PCN; Department. of Medicine, Division of Endocrinology, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Skjaeret T; NorthSea Therapeutics BV, Amsterdam, The Netherlands., Alonso C; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Feigh M; Gubra, Hørsholm, Denmark., Kastelein JJP; Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Friedman SL; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Princen HMG; TNO Metabolic Health Research, Leiden, The Netherlands., Fraser DA; NorthSea Therapeutics BV, Amsterdam, The Netherlands.
Source: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2020 Nov; Vol. 40 (11), pp. 2860-2876.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dual targeting of hepatic fibrosis and atherogenesis by icosabutate, an engineered eicosapentaenoic acid derivative.
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  Data: <searchLink fieldCode="AU" term="%22Stokman+G%22">Stokman G</searchLink>; TNO Metabolic Health Research, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Hoek+AM%22">van den Hoek AM</searchLink>; TNO Metabolic Health Research, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Denker+Thorbekk+D%22">Denker Thorbekk D</searchLink>; Gubra, Hørsholm, Denmark.<br /><searchLink fieldCode="AU" term="%22Pieterman+EJ%22">Pieterman EJ</searchLink>; TNO Metabolic Health Research, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Skovgård+Veidal+S%22">Skovgård Veidal S</searchLink>; Gubra, Hørsholm, Denmark.<br /><searchLink fieldCode="AU" term="%22Basta+B%22">Basta B</searchLink>; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Iruarrizaga-Lejarreta+M%22">Iruarrizaga-Lejarreta M</searchLink>; OWL Metabolomics, Parque Tecnológico de Bizkaia, Zamudio, Spain.<br /><searchLink fieldCode="AU" term="%22van+der+Hoorn+JW%22">van der Hoorn JW</searchLink>; TNO Metabolic Health Research, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Verschuren+L%22">Verschuren L</searchLink>; TNO Microbiology & Systems Biology, Zeist, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Berbée+JFP%22">Berbée JFP</searchLink>; Department. of Medicine, Division of Endocrinology, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rensen+PCN%22">Rensen PCN</searchLink>; Department. of Medicine, Division of Endocrinology, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Skjaeret+T%22">Skjaeret T</searchLink>; NorthSea Therapeutics BV, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Alonso+C%22">Alonso C</searchLink>; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Feigh+M%22">Feigh M</searchLink>; Gubra, Hørsholm, Denmark.<br /><searchLink fieldCode="AU" term="%22Kastelein+JJP%22">Kastelein JJP</searchLink>; Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Friedman+SL%22">Friedman SL</searchLink>; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Princen+HMG%22">Princen HMG</searchLink>; TNO Metabolic Health Research, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Fraser+DA%22">Fraser DA</searchLink>; NorthSea Therapeutics BV, Amsterdam, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101160857%22">Liver international : official journal of the International Association for the Study of the Liver</searchLink> [Liver Int] 2020 Nov; Vol. 40 (11), pp. 2860-2876.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101160857 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1478-3231 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214783223%22">14783223 </searchLink><i>NLM ISO Abbreviation: </i>Liver Int <i>Subsets: </i>MEDLINE
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              Text: 2020 Nov
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