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A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer's Disease and Frontotemporal Dementia Disease Modeling.

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Title: A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer's Disease and Frontotemporal Dementia Disease Modeling.
Authors: Muñoz SS; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia., Engel M; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia., Balez R; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia., Do-Ha D; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia., Cabral-da-Silva MC; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia., Hernández D; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, VIC 3010, Australia.; Department of Surgery, University of Melbourne, Parkville, VIC 3010, Australia.; Centre for Eye Research Australia, Royal Victoria Eye and Ear Hospital, Melbourne, VIC 3002, Australia., Berg T; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia., Fifita JA; Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW 2190, Australia., Grima N; Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW 2190, Australia., Yang S; Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW 2190, Australia., Blair IP; Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW 2190, Australia., Nicholson G; Concord Repatriation General Hospital, University of Sydney ANZAC Research Institute, Sydney, NSW 2006, Australia., Cook AL; Wicking Dementia Research and Education Centre, University of Tasmania, Hobart, TAS 7001, Australia., Hewitt AW; Department of Surgery, University of Melbourne, Parkville, VIC 3010, Australia.; Centre for Eye Research Australia, Royal Victoria Eye and Ear Hospital, Melbourne, VIC 3002, Australia.; School of Medicine, Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS 7000, Australia., Pébay A; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, VIC 3010, Australia.; Department of Surgery, University of Melbourne, Parkville, VIC 3010, Australia.; Centre for Eye Research Australia, Royal Victoria Eye and Ear Hospital, Melbourne, VIC 3002, Australia., Ooi L; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
Source: Cells [Cells] 2020 Sep 02; Vol. 9 (9). Date of Electronic Publication: 2020 Sep 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE
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  Data: A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer's Disease and Frontotemporal Dementia Disease Modeling.
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  Data: <searchLink fieldCode="AU" term="%22Muñoz+SS%22">Muñoz SS</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Engel+M%22">Engel M</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Balez+R%22">Balez R</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Do-Ha+D%22">Do-Ha D</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Cabral-da-Silva+MC%22">Cabral-da-Silva MC</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Hernández+D%22">Hernández D</searchLink>; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, VIC 3010, Australia.; Department of Surgery, University of Melbourne, Parkville, VIC 3010, Australia.; Centre for Eye Research Australia, Royal Victoria Eye and Ear Hospital, Melbourne, VIC 3002, Australia.<br /><searchLink fieldCode="AU" term="%22Berg+T%22">Berg T</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Fifita+JA%22">Fifita JA</searchLink>; Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW 2190, Australia.<br /><searchLink fieldCode="AU" term="%22Grima+N%22">Grima N</searchLink>; Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW 2190, Australia.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW 2190, Australia.<br /><searchLink fieldCode="AU" term="%22Blair+IP%22">Blair IP</searchLink>; Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW 2190, Australia.<br /><searchLink fieldCode="AU" term="%22Nicholson+G%22">Nicholson G</searchLink>; Concord Repatriation General Hospital, University of Sydney ANZAC Research Institute, Sydney, NSW 2006, Australia.<br /><searchLink fieldCode="AU" term="%22Cook+AL%22">Cook AL</searchLink>; Wicking Dementia Research and Education Centre, University of Tasmania, Hobart, TAS 7001, Australia.<br /><searchLink fieldCode="AU" term="%22Hewitt+AW%22">Hewitt AW</searchLink>; Department of Surgery, University of Melbourne, Parkville, VIC 3010, Australia.; Centre for Eye Research Australia, Royal Victoria Eye and Ear Hospital, Melbourne, VIC 3002, Australia.; School of Medicine, Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS 7000, Australia.<br /><searchLink fieldCode="AU" term="%22Pébay+A%22">Pébay A</searchLink>; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, VIC 3010, Australia.; Department of Surgery, University of Melbourne, Parkville, VIC 3010, Australia.; Centre for Eye Research Australia, Royal Victoria Eye and Ear Hospital, Melbourne, VIC 3002, Australia.<br /><searchLink fieldCode="AU" term="%22Ooi+L%22">Ooi L</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
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