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pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise.

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Title: pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise.
Authors: Reddy A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Bozi LHM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA; Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil., Yaghi OK; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA., Mills EL; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Xiao H; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Nicholson HE; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Paschini M; Stem Cell Program, Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA., Paulo JA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Garrity R; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Laznik-Bogoslavski D; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Ferreira JCB; Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil., Carl CS; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Sjøberg KA; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Wojtaszewski JFP; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Jeppesen JF; Global Drug Discovery, Novo Nordisk A/S, Copenhagen, Denmark., Kiens B; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Gygi SP; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Richter EA; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Mathis D; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA., Chouchani ET; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. Electronic address: edwardt_chouchani@dfci.harvard.edu.
Source: Cell [Cell] 2020 Oct 01; Vol. 183 (1), pp. 62-75.e17. Date of Electronic Publication: 2020 Sep 17.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Reddy+A%22">Reddy A</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bozi+LHM%22">Bozi LHM</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA; Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Yaghi+OK%22">Yaghi OK</searchLink>; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Mills+EL%22">Mills EL</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Xiao+H%22">Xiao H</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nicholson+HE%22">Nicholson HE</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Paschini+M%22">Paschini M</searchLink>; Stem Cell Program, Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Paulo+JA%22">Paulo JA</searchLink>; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Garrity+R%22">Garrity R</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Laznik-Bogoslavski+D%22">Laznik-Bogoslavski D</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ferreira+JCB%22">Ferreira JCB</searchLink>; Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Carl+CS%22">Carl CS</searchLink>; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Sjøberg+KA%22">Sjøberg KA</searchLink>; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Wojtaszewski+JFP%22">Wojtaszewski JFP</searchLink>; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Jeppesen+JF%22">Jeppesen JF</searchLink>; Global Drug Discovery, Novo Nordisk A/S, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Kiens+B%22">Kiens B</searchLink>; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Gygi+SP%22">Gygi SP</searchLink>; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Richter+EA%22">Richter EA</searchLink>; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Mathis+D%22">Mathis D</searchLink>; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Chouchani+ET%22">Chouchani ET</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. Electronic address: edwardt_chouchani@dfci.harvard.edu.
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  Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2020 Oct 01; Vol. 183 (1), pp. 62-75.e17. <i>Date of Electronic Publication: </i>2020 Sep 17.
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