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A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics.

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Title: A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics.
Authors: Amann-Zalcenstein D; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Single Cell Open Research Endeavour (SCORE), The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Tian L; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne, Parkville, Victoria, Australia.; Epigenetics and Development Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Schreuder J; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Tomei S; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne, Parkville, Victoria, Australia., Lin DS; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne, Parkville, Victoria, Australia., Fairfax KA; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia., Bolden JE; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., McKenzie MD; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Inflammation Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Jarratt A; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Hilton A; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Jackson JT; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia., Di Rago L; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., McCormack MP; Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia., de Graaf CA; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Stonehouse O; Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne, Parkville, Victoria, Australia.; Epigenetics and Development Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Taoudi S; Epigenetics and Development Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia., Alexander WS; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Nutt SL; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia., Ritchie ME; Epigenetics and Development Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia., Ng AP; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Clinical Haematology, Peter MacCallum Cancer Centre & The Royal Melbourne Hospital, Parkville, Victoria, Australia., Naik SH; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. naik.s@wehi.edu.au.; Single Cell Open Research Endeavour (SCORE), The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. naik.s@wehi.edu.au.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia. naik.s@wehi.edu.au.
Source: Nature immunology [Nat Immunol] 2020 Dec; Vol. 21 (12), pp. 1574-1584. Date of Electronic Publication: 2020 Oct 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE
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  Data: A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics.
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  Data: <searchLink fieldCode="AU" term="%22Amann-Zalcenstein+D%22">Amann-Zalcenstein D</searchLink>; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Single Cell Open Research Endeavour (SCORE), The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Tian+L%22">Tian L</searchLink>; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne, Parkville, Victoria, Australia.; Epigenetics and Development Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Schreuder+J%22">Schreuder J</searchLink>; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Tomei+S%22">Tomei S</searchLink>; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Lin+DS%22">Lin DS</searchLink>; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Fairfax+KA%22">Fairfax KA</searchLink>; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.<br /><searchLink fieldCode="AU" term="%22Bolden+JE%22">Bolden JE</searchLink>; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22McKenzie+MD%22">McKenzie MD</searchLink>; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Inflammation Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Jarratt+A%22">Jarratt A</searchLink>; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Hilton+A%22">Hilton A</searchLink>; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Jackson+JT%22">Jackson JT</searchLink>; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Di+Rago+L%22">Di Rago L</searchLink>; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22McCormack+MP%22">McCormack MP</searchLink>; Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22de+Graaf+CA%22">de Graaf CA</searchLink>; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Stonehouse+O%22">Stonehouse O</searchLink>; Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne, Parkville, Victoria, Australia.; Epigenetics and Development Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Taoudi+S%22">Taoudi S</searchLink>; Epigenetics and Development Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Alexander+WS%22">Alexander WS</searchLink>; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Nutt+SL%22">Nutt SL</searchLink>; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Ritchie+ME%22">Ritchie ME</searchLink>; Epigenetics and Development Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Ng+AP%22">Ng AP</searchLink>; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.; Blood Cells and Blood Cancer Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Clinical Haematology, Peter MacCallum Cancer Centre & The Royal Melbourne Hospital, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Naik+SH%22">Naik SH</searchLink>; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. naik.s@wehi.edu.au.; Single Cell Open Research Endeavour (SCORE), The Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. naik.s@wehi.edu.au.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia. naik.s@wehi.edu.au.
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  Data: <searchLink fieldCode="JN" term="%22100941354%22">Nature immunology</searchLink> [Nat Immunol] 2020 Dec; Vol. 21 (12), pp. 1574-1584. <i>Date of Electronic Publication: </i>2020 Oct 19.
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