Identification of the hydantoin alkaloids parazoanthines as novel CXCR4 antagonists by computational and in vitro functional characterization.
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| Title: | Identification of the hydantoin alkaloids parazoanthines as novel CXCR4 antagonists by computational and in vitro functional characterization. |
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| Authors: | Vitale RM; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078, Pozzuoli, (NA), Italy., Thellung S; Section of Pharmacology, Department of Internal Medicine, University of Genova, 16132 Genova, Italy., Tinto F; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078, Pozzuoli, (NA), Italy., Solari A; Section of Pharmacology, Department of Internal Medicine, University of Genova, 16132 Genova, Italy., Gatti M; Section of Pharmacology, Department of Internal Medicine, University of Genova, 16132 Genova, Italy., Nuzzo G; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078, Pozzuoli, (NA), Italy., Ioannou E; Department of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, Athens 15771, Greece., Roussis V; Department of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, Athens 15771, Greece., Ciavatta ML; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078, Pozzuoli, (NA), Italy., Manzo E; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078, Pozzuoli, (NA), Italy. Electronic address: emanzo@icb.cnr.it., Florio T; Section of Pharmacology, Department of Internal Medicine, University of Genova, 16132 Genova, Italy; IRCCS Policlinico San Martino, 16132 Genova, Italy. Electronic address: tullio.florio@unige.it., Amodeo P; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078, Pozzuoli, (NA), Italy. Electronic address: pamodeo@icb.cnr.it. |
| Source: | Bioorganic chemistry [Bioorg Chem] 2020 Dec; Vol. 105, pp. 104337. Date of Electronic Publication: 2020 Oct 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 33113408 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Identification of the hydantoin alkaloids parazoanthines as novel CXCR4 antagonists by computational and in vitro functional characterization. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Vitale+RM%22">Vitale RM</searchLink>; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078, Pozzuoli, (NA), Italy.<br /><searchLink fieldCode="AU" term="%22Thellung+S%22">Thellung S</searchLink>; Section of Pharmacology, Department of Internal Medicine, University of Genova, 16132 Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Tinto+F%22">Tinto F</searchLink>; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078, Pozzuoli, (NA), Italy.<br /><searchLink fieldCode="AU" term="%22Solari+A%22">Solari A</searchLink>; Section of Pharmacology, Department of Internal Medicine, University of Genova, 16132 Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Gatti+M%22">Gatti M</searchLink>; Section of Pharmacology, Department of Internal Medicine, University of Genova, 16132 Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Nuzzo+G%22">Nuzzo G</searchLink>; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078, Pozzuoli, (NA), Italy.<br /><searchLink fieldCode="AU" term="%22Ioannou+E%22">Ioannou E</searchLink>; Department of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, Athens 15771, Greece.<br /><searchLink fieldCode="AU" term="%22Roussis+V%22">Roussis V</searchLink>; Department of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, Athens 15771, Greece.<br /><searchLink fieldCode="AU" term="%22Ciavatta+ML%22">Ciavatta ML</searchLink>; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078, Pozzuoli, (NA), Italy.<br /><searchLink fieldCode="AU" term="%22Manzo+E%22">Manzo E</searchLink>; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078, Pozzuoli, (NA), Italy. Electronic address: emanzo@icb.cnr.it.<br /><searchLink fieldCode="AU" term="%22Florio+T%22">Florio T</searchLink>; Section of Pharmacology, Department of Internal Medicine, University of Genova, 16132 Genova, Italy; IRCCS Policlinico San Martino, 16132 Genova, Italy. Electronic address: tullio.florio@unige.it.<br /><searchLink fieldCode="AU" term="%22Amodeo+P%22">Amodeo P</searchLink>; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078, Pozzuoli, (NA), Italy. Electronic address: pamodeo@icb.cnr.it. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%221303703%22">Bioorganic chemistry</searchLink> [Bioorg Chem] 2020 Dec; Vol. 105, pp. 104337. <i>Date of Electronic Publication: </i>2020 Oct 06. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1303703 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2120 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200452068%22">00452068 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=33113408 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.bioorg.2020.104337 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 104337 Titles: – TitleFull: Identification of the hydantoin alkaloids parazoanthines as novel CXCR4 antagonists by computational and in vitro functional characterization. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Vitale RM – PersonEntity: Name: NameFull: Thellung S – PersonEntity: Name: NameFull: Tinto F – PersonEntity: Name: NameFull: Solari A – PersonEntity: Name: NameFull: Gatti M – PersonEntity: Name: NameFull: Nuzzo G – PersonEntity: Name: NameFull: Ioannou E – PersonEntity: Name: NameFull: Roussis V – PersonEntity: Name: NameFull: Ciavatta ML – PersonEntity: Name: NameFull: Manzo E – PersonEntity: Name: NameFull: Florio T – PersonEntity: Name: NameFull: Amodeo P IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2020 Dec Type: published Y: 2020 Identifiers: – Type: issn-electronic Value: 1090-2120 Numbering: – Type: volume Value: 105 Titles: – TitleFull: Bioorganic chemistry Type: main |
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