Navitoclax enhances the effectiveness of EGFR-targeted antibody-drug conjugates in PDX models of EGFR-expressing triple-negative breast cancer.
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| Title: | Navitoclax enhances the effectiveness of EGFR-targeted antibody-drug conjugates in PDX models of EGFR-expressing triple-negative breast cancer. |
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| Authors: | Zoeller JJ; Department of Cell Biology and Ludwig Center at Harvard, Harvard Medical School, 240 Longwood Avenue, Boston, MA, 02115, USA., Vagodny A; Department of Cell Biology and Ludwig Center at Harvard, Harvard Medical School, 240 Longwood Avenue, Boston, MA, 02115, USA., Daniels VW; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Taneja K; Department of Pathology, Brigham & Women's Hospital, Boston, MA, USA., Tan BY; Department of Pathology, Brigham & Women's Hospital, Boston, MA, USA., DeRose YS; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Fujita M; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Welm AL; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Letai A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Leverson JD; Oncology Development, AbbVie, North Chicago, IL, USA., Blot V; Oncology Development, AbbVie, North Chicago, IL, USA., Bronson RT; Department of Pathology, Harvard Medical School, Boston, MA, USA., Dillon DA; Department of Pathology, Brigham & Women's Hospital, Boston, MA, USA., Brugge JS; Department of Cell Biology and Ludwig Center at Harvard, Harvard Medical School, 240 Longwood Avenue, Boston, MA, 02115, USA. joan_brugge@hms.harvard.edu. |
| Source: | Breast cancer research : BCR [Breast Cancer Res] 2020 Nov 30; Vol. 22 (1), pp. 132. Date of Electronic Publication: 2020 Nov 30. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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