Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer.

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Title: Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer.
Authors: Levi-Galibov O; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel., Lavon H; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel., Wassermann-Dozorets R; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel., Pevsner-Fischer M; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel., Mayer S; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel., Wershof E; The Francis Crick Institute, London, UK., Stein Y; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel., Brown LE; Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University, Boston, MA, USA., Zhang W; Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University, Boston, MA, USA., Friedman G; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel., Nevo R; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel., Golani O; Department of Life Sciences Core Facilities, The Weizmann Institute of Science, Rehovot, Israel., Katz LH; Gastroenterology Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.; Department of Gastroenterology and Hepatology, Hadassah Medical Center, Jerusalem, Israel., Yaeger R; Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, and Weil Cornell Medical College, New York, NY, USA., Laish I; Gastroenterology Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel., Porco JA; Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University, Boston, MA, USA., Sahai E; The Francis Crick Institute, London, UK., Shouval DS; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.; Pediatric Gastroenterology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel., Kelsen D; Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, and Weil Cornell Medical College, New York, NY, USA., Scherz-Shouval R; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel. ruth.shouval@weizmann.ac.il.
Source: Nature communications [Nat Commun] 2020 Dec 07; Vol. 11 (1), pp. 6245. Date of Electronic Publication: 2020 Dec 07.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer.
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  Data: <searchLink fieldCode="AU" term="%22Levi-Galibov+O%22">Levi-Galibov O</searchLink>; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Lavon+H%22">Lavon H</searchLink>; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Wassermann-Dozorets+R%22">Wassermann-Dozorets R</searchLink>; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Pevsner-Fischer+M%22">Pevsner-Fischer M</searchLink>; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Mayer+S%22">Mayer S</searchLink>; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Wershof+E%22">Wershof E</searchLink>; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Stein+Y%22">Stein Y</searchLink>; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Brown+LE%22">Brown LE</searchLink>; Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Friedman+G%22">Friedman G</searchLink>; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Nevo+R%22">Nevo R</searchLink>; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Golani+O%22">Golani O</searchLink>; Department of Life Sciences Core Facilities, The Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Katz+LH%22">Katz LH</searchLink>; Gastroenterology Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.; Department of Gastroenterology and Hepatology, Hadassah Medical Center, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Yaeger+R%22">Yaeger R</searchLink>; Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, and Weil Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Laish+I%22">Laish I</searchLink>; Gastroenterology Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Porco+JA%22">Porco JA</searchLink>; Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sahai+E%22">Sahai E</searchLink>; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Shouval+DS%22">Shouval DS</searchLink>; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.; Pediatric Gastroenterology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Kelsen+D%22">Kelsen D</searchLink>; Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, and Weil Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Scherz-Shouval+R%22">Scherz-Shouval R</searchLink>; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel. ruth.shouval@weizmann.ac.il.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2020 Dec 07; Vol. 11 (1), pp. 6245. <i>Date of Electronic Publication: </i>2020 Dec 07.
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