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Safety, pharmacokinetics and pharmacodynamics of a topical SYK inhibitor in cutaneous lupus erythematosus: A double-blind Phase Ib study.

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Title: Safety, pharmacokinetics and pharmacodynamics of a topical SYK inhibitor in cutaneous lupus erythematosus: A double-blind Phase Ib study.
Authors: Walker A; GSK, Stevenage, UK., Erwig L; GSK, Stevenage, UK., Foster K; GSK, Stevenage, UK., Nevin K; GSK, Stevenage, UK., Wenzel J; University Hospital of Bonn, Bonn, Germany., Worm M; Division of Allergy and Immunology, Department of Dermatology, Venerology and Allergy, Charité, Berlin, Germany., Williams N; GSK, Stevenage, UK., Ratia N; GSK, Stevenage, UK., Hoang B; GSK, Collegeville, PA, USA., Schneider-Merck T; GSK, Hamburg, Germany., Gisbert S; GSK, Uxbridge, UK., Carnarius H; GSK, Hamburg, Germany., Dickson M; GSK, Stevenage, UK.
Source: Experimental dermatology [Exp Dermatol] 2021 Nov; Vol. 30 (11), pp. 1686-1692. Date of Electronic Publication: 2020 Dec 17.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 9301549 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0625 (Electronic) Linking ISSN: 09066705 NLM ISO Abbreviation: Exp Dermatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety, pharmacokinetics and pharmacodynamics of a topical SYK inhibitor in cutaneous lupus erythematosus: A double-blind Phase Ib study.
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  Data: <searchLink fieldCode="AU" term="%22Walker+A%22">Walker A</searchLink>; GSK, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Erwig+L%22">Erwig L</searchLink>; GSK, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Foster+K%22">Foster K</searchLink>; GSK, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Nevin+K%22">Nevin K</searchLink>; GSK, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Wenzel+J%22">Wenzel J</searchLink>; University Hospital of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Worm+M%22">Worm M</searchLink>; Division of Allergy and Immunology, Department of Dermatology, Venerology and Allergy, Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Williams+N%22">Williams N</searchLink>; GSK, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Ratia+N%22">Ratia N</searchLink>; GSK, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Hoang+B%22">Hoang B</searchLink>; GSK, Collegeville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Schneider-Merck+T%22">Schneider-Merck T</searchLink>; GSK, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gisbert+S%22">Gisbert S</searchLink>; GSK, Uxbridge, UK.<br /><searchLink fieldCode="AU" term="%22Carnarius+H%22">Carnarius H</searchLink>; GSK, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Dickson+M%22">Dickson M</searchLink>; GSK, Stevenage, UK.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Munksgaard%22">Munksgaard </searchLink><i>Country of Publication: </i>Denmark <i>NLM ID: </i>9301549 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1600-0625 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209066705%22">09066705 </searchLink><i>NLM ISO Abbreviation: </i>Exp Dermatol <i>Subsets: </i>MEDLINE
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              Text: 2021 Nov
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