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Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection.

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Title: Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection.
Authors: Hensel N; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Gu Z; Heidelberg Center for Personalised Oncology (DKFZ-HIPO), German Cancer Research Center (DKFZ), Heidelberg, Germany., Sagar; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Wieland D; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Jechow K; Charité - Universitätsmedizin Berlin and Berlin Institute of Health, Digital Health Center, Berlin, Germany., Kemming J; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Llewellyn-Lacey S; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK., Gostick E; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK., Sogukpinar O; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Emmerich F; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Institute for Transfusion Medicine and Gene Therapy, University Medical Center, University of Freiburg, Freiburg, Germany., Price DA; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK.; Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff, UK., Bengsch B; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany., Boettler T; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Neumann-Haefelin C; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Eils R; Charité - Universitätsmedizin Berlin and Berlin Institute of Health, Digital Health Center, Berlin, Germany.; Health Data Science Unit, Faculty of Medicine, University of Heidelberg, Heidelberg, Germany., Conrad C; Charité - Universitätsmedizin Berlin and Berlin Institute of Health, Digital Health Center, Berlin, Germany., Bartenschlager R; Department of Infectious Diseases, Molecular Virology, Heidelberg University, Heidelberg, Germany.; Division Virus-Associated Carcinogenesis, German Cancer Research Center, Heidelberg, Germany.; German Center for Infection Research (DZIF), partner site Heidelberg, Heidelberg, Germany., Grün D; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany., Ishaque N; Charité - Universitätsmedizin Berlin and Berlin Institute of Health, Digital Health Center, Berlin, Germany., Thimme R; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany. robert.thimme@uniklinik-freiburg.de.; Faculty of Medicine, University of Freiburg, Freiburg, Germany. robert.thimme@uniklinik-freiburg.de., Hofmann M; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany. maike.hofmann@uniklinik-freiburg.de.; Faculty of Medicine, University of Freiburg, Freiburg, Germany. maike.hofmann@uniklinik-freiburg.de.
Source: Nature immunology [Nat Immunol] 2021 Feb; Vol. 22 (2), pp. 229-239. Date of Electronic Publication: 2021 Jan 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE
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  Data: Memory-like HCV-specific CD8<superscript>+</superscript> T cells retain a molecular scar after cure of chronic HCV infection.
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  Data: <searchLink fieldCode="AU" term="%22Hensel+N%22">Hensel N</searchLink>; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gu+Z%22">Gu Z</searchLink>; Heidelberg Center for Personalised Oncology (DKFZ-HIPO), German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sagar%22">Sagar</searchLink>; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Wieland+D%22">Wieland D</searchLink>; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jechow+K%22">Jechow K</searchLink>; Charité - Universitätsmedizin Berlin and Berlin Institute of Health, Digital Health Center, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Kemming+J%22">Kemming J</searchLink>; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Llewellyn-Lacey+S%22">Llewellyn-Lacey S</searchLink>; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Gostick+E%22">Gostick E</searchLink>; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Sogukpinar+O%22">Sogukpinar O</searchLink>; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Emmerich+F%22">Emmerich F</searchLink>; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Institute for Transfusion Medicine and Gene Therapy, University Medical Center, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Price+DA%22">Price DA</searchLink>; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK.; Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Bengsch+B%22">Bengsch B</searchLink>; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Boettler+T%22">Boettler T</searchLink>; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Neumann-Haefelin+C%22">Neumann-Haefelin C</searchLink>; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Eils+R%22">Eils R</searchLink>; Charité - Universitätsmedizin Berlin and Berlin Institute of Health, Digital Health Center, Berlin, Germany.; Health Data Science Unit, Faculty of Medicine, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Conrad+C%22">Conrad C</searchLink>; Charité - Universitätsmedizin Berlin and Berlin Institute of Health, Digital Health Center, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Bartenschlager+R%22">Bartenschlager R</searchLink>; Department of Infectious Diseases, Molecular Virology, Heidelberg University, Heidelberg, Germany.; Division Virus-Associated Carcinogenesis, German Cancer Research Center, Heidelberg, Germany.; German Center for Infection Research (DZIF), partner site Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Grün+D%22">Grün D</searchLink>; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ishaque+N%22">Ishaque N</searchLink>; Charité - Universitätsmedizin Berlin and Berlin Institute of Health, Digital Health Center, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Thimme+R%22">Thimme R</searchLink>; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany. robert.thimme@uniklinik-freiburg.de.; Faculty of Medicine, University of Freiburg, Freiburg, Germany. robert.thimme@uniklinik-freiburg.de.<br /><searchLink fieldCode="AU" term="%22Hofmann+M%22">Hofmann M</searchLink>; Department of Medicine II, University Hospital Freiburg, Freiburg, Germany. maike.hofmann@uniklinik-freiburg.de.; Faculty of Medicine, University of Freiburg, Freiburg, Germany. maike.hofmann@uniklinik-freiburg.de.
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  Data: <searchLink fieldCode="JN" term="%22100941354%22">Nature immunology</searchLink> [Nat Immunol] 2021 Feb; Vol. 22 (2), pp. 229-239. <i>Date of Electronic Publication: </i>2021 Jan 04.
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