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Therapeutic afucosylated monoclonal antibody and bispecific T-cell engagers for T-cell acute lymphoblastic leukemia.

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Title: Therapeutic afucosylated monoclonal antibody and bispecific T-cell engagers for T-cell acute lymphoblastic leukemia.
Authors: Caracciolo D; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy., Riillo C; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy., Ballerini A; BiovelocITA srl, Milano, Italy., Gaipa G; Centro Ricerca M. Tettamanti, Clinica Pediatrica Università Milano-Bicocca, Ospedale San Gerardo, Monza, Italy., Lhermitte L; Université de Paris, Institut Necker-Enfants Malades, Institut National de Recherche Médicale U1151, Paris, France.; Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades, Paris, France., Rossi M; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy., Botta C; Hematology Unit, Annunziata Hospital, Cosenza, Italy., Duroyon E; Université de Paris, Institut Necker-Enfants Malades, Institut National de Recherche Médicale U1151, Paris, France.; Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades, Paris, France., Grillone K; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy., Gallo Cantafio ME; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy., Buracchi C; Centro Ricerca M. Tettamanti, Clinica Pediatrica Università Milano-Bicocca, Ospedale San Gerardo, Monza, Italy., Alampi G; Centro Ricerca M. Tettamanti, Clinica Pediatrica Università Milano-Bicocca, Ospedale San Gerardo, Monza, Italy., Gulino A; Tumor Immunology Unit, Department of Health Sciences, Human Pathology Section, University of Palermo, Palermo, Italy., Belmonte B; Tumor Immunology Unit, Department of Health Sciences, Human Pathology Section, University of Palermo, Palermo, Italy., Conforti F; Pathology Unit, Annunziata Hospital, Cosenza, Italy., Golino G; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy., Juli G; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy., Altomare E; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy., Polerà N; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy., Scionti F; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy., Arbitrio M; IRIB-CNR, Catanzaro, Italy., Iannone M; IRIB-CNR, Catanzaro, Italy., Martino M; Stem Cell Transplant Program, Clinical Section, Department of Hemato-Oncology and Radiotherapy, Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria, Italy., Correale P; Medical Oncology Unit, 'Bianchi-Melacrino-Morelli' Grand Metropolitan Hospital, Reggio Calabria, Italy., Talarico G; Immunotransfusion Service Unit, Pugliese-Ciaccio Hospital, Catanzaro, Italy., Ghelli Luserna di Rorà A; Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy., Ferrari A; Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy., Concolino D; Department of Medical and Surgical Sciences, Pediatric Unit, University 'Magna Graecia' of Catanzaro, Catanzaro, Italy., Sestito S; Department of Medical and Surgical Sciences, Pediatric Unit, University 'Magna Graecia' of Catanzaro, Catanzaro, Italy., Pensabene L; Department of Medical and Surgical Sciences, Pediatric Unit, University 'Magna Graecia' of Catanzaro, Catanzaro, Italy., Giordano A; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA., Hildinger M; Evitria, Zurich, Switzerland., Di Martino MT; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy., Martinelli G; Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy., Tripodo C; Tumor Immunology Unit, Department of Health Sciences, Human Pathology Section, University of Palermo, Palermo, Italy., Asnafi V; Université de Paris, Institut Necker-Enfants Malades, Institut National de Recherche Médicale U1151, Paris, France.; Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades, Paris, France., Biondi A; Centro Ricerca M. Tettamanti, Clinica Pediatrica Università Milano-Bicocca, Ospedale San Gerardo, Monza, Italy., Tagliaferri P; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy., Tassone P; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy tassone@unicz.it.; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2021 Feb; Vol. 9 (2).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Print Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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PubType: Academic Journal
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  Data: Therapeutic afucosylated monoclonal antibody and bispecific T-cell engagers for T-cell acute lymphoblastic leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Caracciolo+D%22">Caracciolo D</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Riillo+C%22">Riillo C</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Ballerini+A%22">Ballerini A</searchLink>; BiovelocITA srl, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Gaipa+G%22">Gaipa G</searchLink>; Centro Ricerca M. Tettamanti, Clinica Pediatrica Università Milano-Bicocca, Ospedale San Gerardo, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Lhermitte+L%22">Lhermitte L</searchLink>; Université de Paris, Institut Necker-Enfants Malades, Institut National de Recherche Médicale U1151, Paris, France.; Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades, Paris, France.<br /><searchLink fieldCode="AU" term="%22Rossi+M%22">Rossi M</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Botta+C%22">Botta C</searchLink>; Hematology Unit, Annunziata Hospital, Cosenza, Italy.<br /><searchLink fieldCode="AU" term="%22Duroyon+E%22">Duroyon E</searchLink>; Université de Paris, Institut Necker-Enfants Malades, Institut National de Recherche Médicale U1151, Paris, France.; Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades, Paris, France.<br /><searchLink fieldCode="AU" term="%22Grillone+K%22">Grillone K</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Gallo+Cantafio+ME%22">Gallo Cantafio ME</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Buracchi+C%22">Buracchi C</searchLink>; Centro Ricerca M. Tettamanti, Clinica Pediatrica Università Milano-Bicocca, Ospedale San Gerardo, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Alampi+G%22">Alampi G</searchLink>; Centro Ricerca M. Tettamanti, Clinica Pediatrica Università Milano-Bicocca, Ospedale San Gerardo, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Gulino+A%22">Gulino A</searchLink>; Tumor Immunology Unit, Department of Health Sciences, Human Pathology Section, University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Belmonte+B%22">Belmonte B</searchLink>; Tumor Immunology Unit, Department of Health Sciences, Human Pathology Section, University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Conforti+F%22">Conforti F</searchLink>; Pathology Unit, Annunziata Hospital, Cosenza, Italy.<br /><searchLink fieldCode="AU" term="%22Golino+G%22">Golino G</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Juli+G%22">Juli G</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Altomare+E%22">Altomare E</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Polerà+N%22">Polerà N</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Scionti+F%22">Scionti F</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Arbitrio+M%22">Arbitrio M</searchLink>; IRIB-CNR, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Iannone+M%22">Iannone M</searchLink>; IRIB-CNR, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Martino+M%22">Martino M</searchLink>; Stem Cell Transplant Program, Clinical Section, Department of Hemato-Oncology and Radiotherapy, Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria, Italy.<br /><searchLink fieldCode="AU" term="%22Correale+P%22">Correale P</searchLink>; Medical Oncology Unit, 'Bianchi-Melacrino-Morelli' Grand Metropolitan Hospital, Reggio Calabria, Italy.<br /><searchLink fieldCode="AU" term="%22Talarico+G%22">Talarico G</searchLink>; Immunotransfusion Service Unit, Pugliese-Ciaccio Hospital, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Ghelli+Luserna+di+Rorà+A%22">Ghelli Luserna di Rorà A</searchLink>; Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrari+A%22">Ferrari A</searchLink>; Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy.<br /><searchLink fieldCode="AU" term="%22Concolino+D%22">Concolino D</searchLink>; Department of Medical and Surgical Sciences, Pediatric Unit, University 'Magna Graecia' of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Sestito+S%22">Sestito S</searchLink>; Department of Medical and Surgical Sciences, Pediatric Unit, University 'Magna Graecia' of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Pensabene+L%22">Pensabene L</searchLink>; Department of Medical and Surgical Sciences, Pediatric Unit, University 'Magna Graecia' of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Giordano+A%22">Giordano A</searchLink>; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Hildinger+M%22">Hildinger M</searchLink>; Evitria, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Di+Martino+MT%22">Di Martino MT</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Martinelli+G%22">Martinelli G</searchLink>; Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy.<br /><searchLink fieldCode="AU" term="%22Tripodo+C%22">Tripodo C</searchLink>; Tumor Immunology Unit, Department of Health Sciences, Human Pathology Section, University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Asnafi+V%22">Asnafi V</searchLink>; Université de Paris, Institut Necker-Enfants Malades, Institut National de Recherche Médicale U1151, Paris, France.; Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades, Paris, France.<br /><searchLink fieldCode="AU" term="%22Biondi+A%22">Biondi A</searchLink>; Centro Ricerca M. Tettamanti, Clinica Pediatrica Università Milano-Bicocca, Ospedale San Gerardo, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Tagliaferri+P%22">Tagliaferri P</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Tassone+P%22">Tassone P</searchLink>; Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy tassone@unicz.it.; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA.
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