Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial.
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| Title: | Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial. |
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| Authors: | Cascone T; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. tcascone@mdanderson.org., William WN Jr; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Oncology Center, Hospital BP, a Beneficencia Portuguesa de São Paulo, São Paulo, Brazil., Weissferdt A; Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Leung CH; Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lin HY; Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Pataer A; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Godoy MCB; Thoracic Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Carter BW; Thoracic Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Federico L; Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Reuben A; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Khan MAW; Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Dejima H; Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Teikyo University School of Medicine, Itabashi, Tokyo, Japan., Francisco-Cruz A; Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Parra ER; Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Solis LM; Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Fujimoto J; Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Tran HT; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kalhor N; Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Fossella FV; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Mott FE; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Tsao AS; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Blumenschein G Jr; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Le X; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhang J; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Skoulidis F; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kurie JM; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Altan M; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lu C; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Glisson BS; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Byers LA; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Elamin YY; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Mehran RJ; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Rice DC; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Walsh GL; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Hofstetter WL; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Roth JA; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Antonoff MB; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kadara H; Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Haymaker C; Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Bernatchez C; Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Ajami NJ; Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Jenq RR; Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; CPRIT Scholar in Cancer Research, Houston, TX, USA., Sharma P; Genitourinary Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Immunology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Allison JP; Immunology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Futreal A; Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Wargo JA; Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Wistuba II; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Swisher SG; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lee JJ; Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Gibbons DL; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Vaporciyan AA; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Heymach JV; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Sepesi B; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA. |
| Source: | Nature medicine [Nat Med] 2021 Mar; Vol. 27 (3), pp. 504-514. Date of Electronic Publication: 2021 Feb 18. |
| Publication Type: | Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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