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Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries.

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Title: Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries.
Authors: Gharahkhani P; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia. Puya.Gharahkhani@qimrberghofer.edu.au., Jorgenson E; Division of Research, Kaiser Permanente Northern California (KPNC), Oakland, CA, USA., Hysi P; Twin Research and Genetic Epidemiology, King's College London, London, UK., Khawaja AP; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK., Pendergrass S; Geisinger Research, Biomedical and Translational Informatics Institute, Danville, PA, USA., Han X; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Ong JS; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Hewitt AW; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia.; Centre for Eye Research Australia, University of Melbourne, Melbourne, VIC, Australia., Segrè AV; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA., Rouhana JM; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA., Hamel AR; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA., Igo RP Jr; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Choquet H; Division of Research, Kaiser Permanente Northern California (KPNC), Oakland, CA, USA., Qassim A; Department of Ophthalmology, Flinders University, Bedford Park, SA, Australia., Josyula NS; Geisinger Research, Biomedical and Translational Informatics Institute, Rockville, MD, USA., Cooke Bailey JN; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.; Cleveland Institute for Computational Biology, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Bonnemaijer PWM; Depatment of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; The Rotterdam Eye Hospital, Rotterdam, The Netherlands., Iglesias A; Depatment of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands., Siggs OM; Department of Ophthalmology, Flinders University, Bedford Park, SA, Australia., Young TL; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Thiadens AAHJ; Depatment of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands., Karjalainen J; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Uebe S; Institute of Human Genetics, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität, Erlangen-Nürnberg, Erlangen, Germany., Melles RB; Department of Ophthalmology, KPNC, Redwood City, CA, USA., Nair KS; Department of Ophthalmology, School of Medicine, University of California San Francisco (UCSF), San Francisco, CA, USA., Luben R; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK., Simcoe M; Twin Research and Genetic Epidemiology, King's College London, London, UK.; Department of Ophthalmology, Kings College London, London, United Kingdom.; Institute of Ophthalmology, University College London, London, UK., Amersinghe N; University Hospital Southampton NHS Foundation Trust, Southampton, UK., Cree AJ; Faculty of Medicine, University of Southampton, Southampton, UK., Hohn R; Department of Ophthalmology, Inselspital, University Hospital Bern, University of Bern, Bern, Germany.; Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Poplawski A; Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Mainz, Mainz, Germany., Chen LJ; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China., Rong SS; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China., Aung T; Singapore Eye Research Institute, Singapore National Eye Certre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Vithana EN; Singapore Eye Research Institute, Singapore National Eye Certre, Singapore, Singapore.; Duke-National University of Singapore Medical School, Singapore, Republic of Singapore., Tamiya G; Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.; RIKEN Center for Advanced Intelligence Project, 1-4-1 Nihonbashi, Chuo-ku, Tokyo, Japan., Shiga Y; Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan., Yamamoto M; Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan., Nakazawa T; Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.; Department of Retinal Disease Control, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.; Department of Advanced Ophthalmic Medicine, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.; Department of Ophthalmic Imaging and Information Analytics, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan., Currant H; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK., Birney E; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK., Wang X; 23 and Me Inc., San Francisco, CA, USA., Auton A; 23 and Me Inc., San Francisco, CA, USA., Lupton MK; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Ashaye A; Department of Ophthalmology, University of Ibadan, Ibadan, Nigeria., Olawoye O; Department of Ophthalmology, University of Ibadan, Ibadan, Nigeria., Williams SE; Division of Ophthalmology, Department of Neurosciences, University of the Witwatersrand, Johannesburg, South Africa., Akafo S; Unit of Ophthalmology, Department of Surgery, University of Ghana Medical School, Accra, Ghana., Ramsay M; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Hashimoto K; Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan., Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan., Akiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Momozawa Y; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Foster PJ; National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital National Health Service Foundation Trust & UCL Institute of Ophthalmology, London, UK.; UCL Institute of Ophthalmology, University College London, London, UK., Khaw PT; National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital National Health Service Foundation Trust & UCL Institute of Ophthalmology, London, UK.; UCL Institute of Ophthalmology, University College London, London, UK., Morgan JE; Cardiff Centre for Vision Sciences, College of Biomedical and Life Sciences, Maindy Road, Cardiff University, Cardiff, UK., Strouthidis NG; National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital National Health Service Foundation Trust & UCL Institute of Ophthalmology, London, UK.; UCL Institute of Ophthalmology, University College London, London, UK., Kraft P; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Kang JH; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Pang CP; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China., Pasutto F; Institute of Human Genetics, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität, Erlangen-Nürnberg, Erlangen, Germany., Mitchell P; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney, Sydney, NSW, Australia., Lotery AJ; University Hospital Southampton NHS Foundation Trust, Southampton, UK.; Faculty of Medicine, University of Southampton, Southampton, UK., Palotie A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Psychiatric & Neurodevelopmental Genetics Unit, Departments of Psychiatry and Neurology, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., van Duijn C; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Haines JL; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.; Cleveland Institute for Computational Biology, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Hammond C; Twin Research and Genetic Epidemiology, King's College London, London, UK., Pasquale LR; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Klaver CCW; Depatment of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; Department of Ophthalmology, Radboud University Medical Center, Nijmegen, The Netherlands.; Institute for Molecular and Clinical Ophthalmology, Basel, Switzerland., Hauser M; Department of Medicine, Duke University, Durham, NC, USA.; Department of Ophthalmology, Duke University, Durham, NC, USA.; Singapore Eye Research Institute, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Khor CC; Division of Human Genetics, Genome Institute of Singapore, Singapore, Singapore., Mackey DA; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia.; Centre for Eye Research Australia, University of Melbourne, Melbourne, VIC, Australia.; Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Nedlands, WA, Australia., Kubo M; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Certre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Craig JE; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, SA, Australia., MacGregor S; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Wiggs JL; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Corporate Authors: NEIGHBORHOOD consortium, ANZRAG consortium, Biobank Japan project, FinnGen study, UK Biobank Eye and Vision Consortium, GIGA study group, 23 and Me Research Team
Source: Nature communications [Nat Commun] 2021 Feb 24; Vol. 12 (1), pp. 1258. Date of Electronic Publication: 2021 Feb 24.
Publication Type: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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Items – Name: Title
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  Data: Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Gharahkhani+P%22">Gharahkhani P</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia. Puya.Gharahkhani@qimrberghofer.edu.au.<br /><searchLink fieldCode="AU" term="%22Jorgenson+E%22">Jorgenson E</searchLink>; Division of Research, Kaiser Permanente Northern California (KPNC), Oakland, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hysi+P%22">Hysi P</searchLink>; Twin Research and Genetic Epidemiology, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Khawaja+AP%22">Khawaja AP</searchLink>; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Pendergrass+S%22">Pendergrass S</searchLink>; Geisinger Research, Biomedical and Translational Informatics Institute, Danville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Han+X%22">Han X</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Ong+JS%22">Ong JS</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Hewitt+AW%22">Hewitt AW</searchLink>; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia.; Centre for Eye Research Australia, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Segrè+AV%22">Segrè AV</searchLink>; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rouhana+JM%22">Rouhana JM</searchLink>; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hamel+AR%22">Hamel AR</searchLink>; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Igo+RP+Jr%22">Igo RP Jr</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Choquet+H%22">Choquet H</searchLink>; Division of Research, Kaiser Permanente Northern California (KPNC), Oakland, CA, USA.<br /><searchLink fieldCode="AU" term="%22Qassim+A%22">Qassim A</searchLink>; Department of Ophthalmology, Flinders University, Bedford Park, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Josyula+NS%22">Josyula NS</searchLink>; Geisinger Research, Biomedical and Translational Informatics Institute, Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Cooke+Bailey+JN%22">Cooke Bailey JN</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.; Cleveland Institute for Computational Biology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Bonnemaijer+PWM%22">Bonnemaijer PWM</searchLink>; Depatment of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; The Rotterdam Eye Hospital, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Iglesias+A%22">Iglesias A</searchLink>; Depatment of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Siggs+OM%22">Siggs OM</searchLink>; Department of Ophthalmology, Flinders University, Bedford Park, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Young+TL%22">Young TL</searchLink>; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Vitart+V%22">Vitart V</searchLink>; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Thiadens+AAHJ%22">Thiadens AAHJ</searchLink>; Depatment of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Karjalainen+J%22">Karjalainen J</searchLink>; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Uebe+S%22">Uebe S</searchLink>; Institute of Human Genetics, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität, Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Melles+RB%22">Melles RB</searchLink>; Department of Ophthalmology, KPNC, Redwood City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nair+KS%22">Nair KS</searchLink>; Department of Ophthalmology, School of Medicine, University of California San Francisco (UCSF), San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Luben+R%22">Luben R</searchLink>; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Simcoe+M%22">Simcoe M</searchLink>; Twin Research and Genetic Epidemiology, King's College London, London, UK.; Department of Ophthalmology, Kings College London, London, United Kingdom.; Institute of Ophthalmology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Amersinghe+N%22">Amersinghe N</searchLink>; University Hospital Southampton NHS Foundation Trust, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Cree+AJ%22">Cree AJ</searchLink>; Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Hohn+R%22">Hohn R</searchLink>; Department of Ophthalmology, Inselspital, University Hospital Bern, University of Bern, Bern, Germany.; Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Poplawski+A%22">Poplawski A</searchLink>; Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Mainz, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Chen+LJ%22">Chen LJ</searchLink>; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Rong+SS%22">Rong SS</searchLink>; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Aung+T%22">Aung T</searchLink>; Singapore Eye Research Institute, Singapore National Eye Certre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Vithana+EN%22">Vithana EN</searchLink>; Singapore Eye Research Institute, Singapore National Eye Certre, Singapore, Singapore.; Duke-National University of Singapore Medical School, Singapore, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Tamiya+G%22">Tamiya G</searchLink>; Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.; RIKEN Center for Advanced Intelligence Project, 1-4-1 Nihonbashi, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shiga+Y%22">Shiga Y</searchLink>; Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+M%22">Yamamoto M</searchLink>; Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Nakazawa+T%22">Nakazawa T</searchLink>; Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.; Department of Retinal Disease Control, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.; Department of Advanced Ophthalmic Medicine, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.; Department of Ophthalmic Imaging and Information Analytics, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Currant+H%22">Currant H</searchLink>; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Birney+E%22">Birney E</searchLink>; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; 23 and Me Inc., San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Auton+A%22">Auton A</searchLink>; 23 and Me Inc., San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lupton+MK%22">Lupton MK</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Martin+NG%22">Martin NG</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Ashaye+A%22">Ashaye A</searchLink>; Department of Ophthalmology, University of Ibadan, Ibadan, Nigeria.<br /><searchLink fieldCode="AU" term="%22Olawoye+O%22">Olawoye O</searchLink>; Department of Ophthalmology, University of Ibadan, Ibadan, Nigeria.<br /><searchLink fieldCode="AU" term="%22Williams+SE%22">Williams SE</searchLink>; Division of Ophthalmology, Department of Neurosciences, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Akafo+S%22">Akafo S</searchLink>; Unit of Ophthalmology, Department of Surgery, University of Ghana Medical School, Accra, Ghana.<br /><searchLink fieldCode="AU" term="%22Ramsay+M%22">Ramsay M</searchLink>; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Hashimoto+K%22">Hashimoto K</searchLink>; Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Kamatani+Y%22">Kamatani Y</searchLink>; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Akiyama+M%22">Akiyama M</searchLink>; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Momozawa+Y%22">Momozawa Y</searchLink>; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Foster+PJ%22">Foster PJ</searchLink>; National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital National Health Service Foundation Trust & UCL Institute of Ophthalmology, London, UK.; UCL Institute of Ophthalmology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Khaw+PT%22">Khaw PT</searchLink>; National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital National Health Service Foundation Trust & UCL Institute of Ophthalmology, London, UK.; UCL Institute of Ophthalmology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Morgan+JE%22">Morgan JE</searchLink>; Cardiff Centre for Vision Sciences, College of Biomedical and Life Sciences, Maindy Road, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Strouthidis+NG%22">Strouthidis NG</searchLink>; National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital National Health Service Foundation Trust & UCL Institute of Ophthalmology, London, UK.; 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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2021 Feb 24; Vol. 12 (1), pp. 1258. <i>Date of Electronic Publication: </i>2021 Feb 24.
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