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Functional States in Tumor-Initiating Cell Differentiation in Human Colorectal Cancer.

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Title: Functional States in Tumor-Initiating Cell Differentiation in Human Colorectal Cancer.
Authors: Zowada MK; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.; Department of Translational Medical Oncology, NCT Dresden and DKFZ, 01307 Dresden, Germany.; Faculty of Biosciences, Heidelberg University, 69120 Heidelberg, Germany., Tirier SM; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, 69120 Heidelberg, Germany.; Division of Chromatin Networks, DKFZ Heidelberg, 69120 Heidelberg, Germany., Dieter SM; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.; Department of Translational Medical Oncology, NCT Dresden and DKFZ, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), 69120 Heidelberg, Germany., Krieger TG; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, 69120 Heidelberg, Germany.; Digital Health Center, Berlin Institute of Health (BIH) and Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany., Oberlack A; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany., Chua RL; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, 69120 Heidelberg, Germany.; Digital Health Center, Berlin Institute of Health (BIH) and Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany., Huerta M; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.; Department of Translational Medical Oncology, NCT Dresden and DKFZ, 01307 Dresden, Germany., Ten FW; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, 69120 Heidelberg, Germany.; Digital Health Center, Berlin Institute of Health (BIH) and Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany., Laaber K; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.; Department of Translational Medical Oncology, NCT Dresden and DKFZ, 01307 Dresden, Germany.; Faculty of Biosciences, Heidelberg University, 69120 Heidelberg, Germany., Park J; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Digital Health Center, Berlin Institute of Health (BIH) and Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany., Jechow K; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, 69120 Heidelberg, Germany.; Digital Health Center, Berlin Institute of Health (BIH) and Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany., Müller T; Division of Proteomics of Stem Cells and Cancer, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany., Kalxdorf M; Division of Proteomics of Stem Cells and Cancer, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany., Kriegsmann M; Institute of Pathology, Heidelberg University Hospital, 69120 Heidelberg, Germany., Kriegsmann K; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, 69120 Heidelberg, Germany., Herbst F; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.; Department of Translational Medical Oncology, NCT Dresden and DKFZ, 01307 Dresden, Germany., Krijgsveld J; Division of Proteomics of Stem Cells and Cancer, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany., Schneider M; Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, 69120 Heidelberg, Germany., Eils R; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, 69120 Heidelberg, Germany.; Digital Health Center, Berlin Institute of Health (BIH) and Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120 Heidelberg, Germany., Glimm H; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.; Department of Translational Medical Oncology, NCT Dresden and DKFZ, 01307 Dresden, Germany.; Center for Personalized Oncology, University Hospital Carl Gustav Carus Dresden at Technische Universität (TU) Dresden, 01307 Dresden, Germany.; DKTK, 01307 Dresden, Germany., Conrad C; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, 69120 Heidelberg, Germany.; Digital Health Center, Berlin Institute of Health (BIH) and Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany., Ball CR; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.; Department of Translational Medical Oncology, NCT Dresden and DKFZ, 01307 Dresden, Germany.; Center for Personalized Oncology, University Hospital Carl Gustav Carus Dresden at Technische Universität (TU) Dresden, 01307 Dresden, Germany.; DKTK, 01307 Dresden, Germany.
Source: Cancers [Cancers (Basel)] 2021 Mar 04; Vol. 13 (5). Date of Electronic Publication: 2021 Mar 04.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE
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  Data: Functional States in Tumor-Initiating Cell Differentiation in Human Colorectal Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Zowada+MK%22">Zowada MK</searchLink>; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.; Department of Translational Medical Oncology, NCT Dresden and DKFZ, 01307 Dresden, Germany.; Faculty of Biosciences, Heidelberg University, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Tirier+SM%22">Tirier SM</searchLink>; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, 69120 Heidelberg, Germany.; Division of Chromatin Networks, DKFZ Heidelberg, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Dieter+SM%22">Dieter SM</searchLink>; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.; Department of Translational Medical Oncology, NCT Dresden and DKFZ, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Krieger+TG%22">Krieger TG</searchLink>; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, 69120 Heidelberg, Germany.; Digital Health Center, Berlin Institute of Health (BIH) and Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Oberlack+A%22">Oberlack A</searchLink>; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Chua+RL%22">Chua RL</searchLink>; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, 69120 Heidelberg, Germany.; 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Division of Proteomics of Stem Cells and Cancer, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+M%22">Schneider M</searchLink>; Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Eils+R%22">Eils R</searchLink>; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, 69120 Heidelberg, Germany.; Digital Health Center, Berlin Institute of Health (BIH) and Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Glimm+H%22">Glimm H</searchLink>; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.; Department of Translational Medical Oncology, NCT Dresden and DKFZ, 01307 Dresden, Germany.; Center for Personalized Oncology, University Hospital Carl Gustav Carus Dresden at Technische Universität (TU) Dresden, 01307 Dresden, Germany.; DKTK, 01307 Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Conrad+C%22">Conrad C</searchLink>; Division of Theoretical Bioinformatics, DKFZ Heidelberg, 69120 Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, 69120 Heidelberg, Germany.; Digital Health Center, Berlin Institute of Health (BIH) and Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Ball+CR%22">Ball CR</searchLink>; Translational Functional Cancer Genomics, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.; 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