Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
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| Title: | Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology. |
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| Authors: | Baglietto-Vargas D; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA.; Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain., Forner S; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA., Cai L; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA., Martini AC; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA., Trujillo-Estrada L; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain., Swarup V; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA., Nguyen MMT; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA., Do Huynh K; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA., Javonillo DI; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA., Tran KM; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA., Phan J; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA., Jiang S; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA., Kramár EA; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA., Nuñez-Diaz C; Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain., Balderrama-Gutierrez G; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA., Garcia F; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA., Childs J; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA., Rodriguez-Ortiz CJ; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Division of Occupational and Environmental Medicine, Department of Medicine. Center for Occupational and Environmental Health (COEH), University of California, Irvine, CA, USA., Garcia-Leon JA; Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain., Kitazawa M; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Division of Occupational and Environmental Medicine, Department of Medicine. Center for Occupational and Environmental Health (COEH), University of California, Irvine, CA, USA., Shahnawaz M; The Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Matheos DP; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA., Ma X; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA., Da Cunha C; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA., Walls KC; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA., Ager RR; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA., Soto C; The Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Gutierrez A; Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain., Moreno-Gonzalez I; Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain.; The Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Mortazavi A; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA., Tenner AJ; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA.; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, USA., MacGregor GR; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA., Wood M; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA., Green KN; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA. kngreen@uci.edu.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA. kngreen@uci.edu., LaFerla FM; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA. laferla@uci.edu.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA. laferla@uci.edu. |
| Source: | Nature communications [Nat Commun] 2021 Apr 23; Vol. 12 (1), pp. 2421. Date of Electronic Publication: 2021 Apr 23. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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