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Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway.

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Title: Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway.
Authors: Dinh TTH; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Ph.D. Program in Human Biology, School of Integrative and Global Majors (SIGMA), University of Tsukuba, Tsukuba, Japan.; Department of Traditional Medicine, University of Medicine and Pharmacy, Ho Chi Minh City, Viet Nam.; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Iseki H; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Japan., Mizuno S; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Iijima-Mizuno S; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Experimental Animal Division, RIKEN BioResource Research Center, Tsukuba, Japan., Tanimoto Y; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Daitoku Y; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Kato K; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Hamada Y; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Hasan ASH; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Doctor's Program in Biomedical Sciences, Graduate School of Comprehensive Human Science, University of Tsukuba, Tsukuba, Japan., Suzuki H; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Doctor's Program in Biomedical Sciences, Graduate School of Comprehensive Human Science, University of Tsukuba, Tsukuba, Japan., Murata K; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Muratani M; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Department of Genome Biology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Ema M; Department of Stem Cells and Human Disease Models, Research Center for Animal Life Science, Shiga University of Medical Science, Otsu, Japan.; Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan., Kim JD; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, Japan.; Division of Complex Bioscience Research, Department of Research and Development, Institute of National Medicine, University of Toyama, Toyama, Japan., Ishida J; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, Japan., Fukamizu A; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, Japan., Kato M; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Department of Experimental Pathology, Faculty of. Medicine, University of Tsukuba, Tsukuba, Japan., Takahashi S; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Yagami KI; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Wilson V; MRC Centre for Regenerative Medicine, School of Biological Sciences, SCRM Building, The University of Edinburgh, Edinburgh, United Kingdom., Arkell RM; John Curtin School of Medical Research, The Australian National University, Canberra, Australia., Sugiyama F; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Source: ELife [Elife] 2021 May 05; Vol. 10. Date of Electronic Publication: 2021 May 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
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  Data: Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway.
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  Data: <searchLink fieldCode="AU" term="%22Dinh+TTH%22">Dinh TTH</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Ph.D. Program in Human Biology, School of Integrative and Global Majors (SIGMA), University of Tsukuba, Tsukuba, Japan.; Department of Traditional Medicine, University of Medicine and Pharmacy, Ho Chi Minh City, Viet Nam.; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Iseki+H%22">Iseki H</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Mizuno+S%22">Mizuno S</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Iijima-Mizuno+S%22">Iijima-Mizuno S</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Experimental Animal Division, RIKEN BioResource Research Center, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Tanimoto+Y%22">Tanimoto Y</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Daitoku+Y%22">Daitoku Y</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+K%22">Kato K</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Hamada+Y%22">Hamada Y</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Hasan+ASH%22">Hasan ASH</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Doctor's Program in Biomedical Sciences, Graduate School of Comprehensive Human Science, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+H%22">Suzuki H</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Doctor's Program in Biomedical Sciences, Graduate School of Comprehensive Human Science, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Murata+K%22">Murata K</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Muratani+M%22">Muratani M</searchLink>; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Department of Genome Biology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Ema+M%22">Ema M</searchLink>; Department of Stem Cells and Human Disease Models, Research Center for Animal Life Science, Shiga University of Medical Science, Otsu, Japan.; Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Kim+JD%22">Kim JD</searchLink>; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, Japan.; Division of Complex Bioscience Research, Department of Research and Development, Institute of National Medicine, University of Toyama, Toyama, Japan.<br /><searchLink fieldCode="AU" term="%22Ishida+J%22">Ishida J</searchLink>; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Fukamizu+A%22">Fukamizu A</searchLink>; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+M%22">Kato M</searchLink>; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Department of Experimental Pathology, Faculty of. Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+S%22">Takahashi S</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Yagami+KI%22">Yagami KI</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Wilson+V%22">Wilson V</searchLink>; MRC Centre for Regenerative Medicine, School of Biological Sciences, SCRM Building, The University of Edinburgh, Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Arkell+RM%22">Arkell RM</searchLink>; John Curtin School of Medical Research, The Australian National University, Canberra, Australia.<br /><searchLink fieldCode="AU" term="%22Sugiyama+F%22">Sugiyama F</searchLink>; Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
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