Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function.

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Title: Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function.
Authors: Rohrer B; Department of Ophthalmology, Medical University of South Carolina, Charleston, SC 29425, USA.; Ralph H. Johnson VA Medical Center, Division of Research, Charleston, SC 29401, USA., Biswal MR; Department of Pharmaceutical Sciences, Taneja College of Pharmacy, University of South Florida, Tampa, FL 33612, USA., Obert E; Department of Ophthalmology, Medical University of South Carolina, Charleston, SC 29425, USA., Dang Y; Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA., Su Y; Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA., Zuo X; Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA., Fogelgren B; Department of Anatomy, Biochemistry, and Physiology, University of Hawaii at Manoa, Honolulu, HI 96813, USA., Kondkar AA; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh 11411, Saudi Arabia., Lobo GP; Department of Ophthalmology, Medical University of South Carolina, Charleston, SC 29425, USA.; Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.; Department of Ophthalmology and Visual Neurosciences, Lions Research Building, 2001 6th Street SE., Room 225, University of Minnesota, Minneapolis, MN 55455, USA., Lipschutz JH; Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.; Department of Medicine, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC 29425, USA.
Source: International journal of molecular sciences [Int J Mol Sci] 2021 May 11; Vol. 22 (10). Date of Electronic Publication: 2021 May 11.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
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  Data: Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function.
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  Data: <searchLink fieldCode="AU" term="%22Rohrer+B%22">Rohrer B</searchLink>; Department of Ophthalmology, Medical University of South Carolina, Charleston, SC 29425, USA.; Ralph H. Johnson VA Medical Center, Division of Research, Charleston, SC 29401, USA.<br /><searchLink fieldCode="AU" term="%22Biswal+MR%22">Biswal MR</searchLink>; Department of Pharmaceutical Sciences, Taneja College of Pharmacy, University of South Florida, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Obert+E%22">Obert E</searchLink>; Department of Ophthalmology, Medical University of South Carolina, Charleston, SC 29425, USA.<br /><searchLink fieldCode="AU" term="%22Dang+Y%22">Dang Y</searchLink>; Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.<br /><searchLink fieldCode="AU" term="%22Su+Y%22">Su Y</searchLink>; Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.<br /><searchLink fieldCode="AU" term="%22Zuo+X%22">Zuo X</searchLink>; Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.<br /><searchLink fieldCode="AU" term="%22Fogelgren+B%22">Fogelgren B</searchLink>; Department of Anatomy, Biochemistry, and Physiology, University of Hawaii at Manoa, Honolulu, HI 96813, USA.<br /><searchLink fieldCode="AU" term="%22Kondkar+AA%22">Kondkar AA</searchLink>; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh 11411, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Lobo+GP%22">Lobo GP</searchLink>; Department of Ophthalmology, Medical University of South Carolina, Charleston, SC 29425, USA.; Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.; Department of Ophthalmology and Visual Neurosciences, Lions Research Building, 2001 6th Street SE., Room 225, University of Minnesota, Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Lipschutz+JH%22">Lipschutz JH</searchLink>; Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.; Department of Medicine, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC 29425, USA.
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  Data: <searchLink fieldCode="JN" term="%22101092791%22">International journal of molecular sciences</searchLink> [Int J Mol Sci] 2021 May 11; Vol. 22 (10). <i>Date of Electronic Publication: </i>2021 May 11.
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