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Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis.

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Title: Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis.
Authors: Bah GS; Institut de Recherche Agricole pour le Développement, Centre Régional de Wakwa, Ngaoundéré, Cameroun., Schneckener S; Bayer AG, Engineering & Technology, Applied Mathematics, Leverkusen, Germany., Hahnel SR; Bayer Animal Health GmbH, Drug Discovery & External Innovation, Monheim am Rhein, Germany., Bayang NH; Institut de Recherche Agricole pour le Développement, Centre Régional de Wakwa, Ngaoundéré, Cameroun., Fieseler H; Bayer Animal Health GmbH, Drug Discovery & External Innovation, Monheim am Rhein, Germany., Schmuck GM; Bayer Animal Health GmbH, Drug Discovery & External Innovation, Monheim am Rhein, Germany., Krebber R; Bayer AG, Crop Science Division, Research & Development-Regulatory Science-Human Safety-Residue Analysis, Monheim am Rhein, Germany., Sarr A; INVENesis Sarl, St-Blaise (NE), Switzerland., Terjung C; Bayer AG, Pharmaceuticals, DMPK, Wuppertal, Germany., Ngangyung HF; Institut de Recherche Agricole pour le Développement, Centre Régional de Wakwa, Ngaoundéré, Cameroun., Ekale DD; Institut de Recherche Agricole pour le Développement, Centre Régional de Wakwa, Ngaoundéré, Cameroun., Mfopit YM; Institut de Recherche Agricole pour le Développement, Centre Régional de Wakwa, Ngaoundéré, Cameroun., Rufener L; INVENesis Sarl, St-Blaise (NE), Switzerland., Graham-Brown J; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Tanya VN; Institut de Recherche Agricole pour le Développement, Centre Régional de Wakwa, Ngaoundéré, Cameroun.; Cameroon Academy of Sciences, Yaoundé, Cameroon., Glenschek-Sieberth M; Bayer AG, Pharmaceuticals, Wuppertal, Germany., Kulke D; Bayer Animal Health GmbH, Drug Discovery & External Innovation, Monheim am Rhein, Germany., Makepeace BL; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.
Source: PLoS pathogens [PLoS Pathog] 2021 Jun 02; Vol. 17 (6), pp. e1009601. Date of Electronic Publication: 2021 Jun 02 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis.
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  Data: <searchLink fieldCode="AU" term="%22Bah+GS%22">Bah GS</searchLink>; Institut de Recherche Agricole pour le Développement, Centre Régional de Wakwa, Ngaoundéré, Cameroun.<br /><searchLink fieldCode="AU" term="%22Schneckener+S%22">Schneckener S</searchLink>; Bayer AG, Engineering & Technology, Applied Mathematics, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Hahnel+SR%22">Hahnel SR</searchLink>; Bayer Animal Health GmbH, Drug Discovery & External Innovation, Monheim am Rhein, Germany.<br /><searchLink fieldCode="AU" term="%22Bayang+NH%22">Bayang NH</searchLink>; Institut de Recherche Agricole pour le Développement, Centre Régional de Wakwa, Ngaoundéré, Cameroun.<br /><searchLink fieldCode="AU" term="%22Fieseler+H%22">Fieseler H</searchLink>; Bayer Animal Health GmbH, Drug Discovery & External Innovation, Monheim am Rhein, Germany.<br /><searchLink fieldCode="AU" term="%22Schmuck+GM%22">Schmuck GM</searchLink>; Bayer Animal Health GmbH, Drug Discovery & External Innovation, Monheim am Rhein, Germany.<br /><searchLink fieldCode="AU" term="%22Krebber+R%22">Krebber R</searchLink>; Bayer AG, Crop Science Division, Research & Development-Regulatory Science-Human Safety-Residue Analysis, Monheim am Rhein, Germany.<br /><searchLink fieldCode="AU" term="%22Sarr+A%22">Sarr A</searchLink>; INVENesis Sarl, St-Blaise (NE), Switzerland.<br /><searchLink fieldCode="AU" term="%22Terjung+C%22">Terjung C</searchLink>; Bayer AG, Pharmaceuticals, DMPK, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Ngangyung+HF%22">Ngangyung HF</searchLink>; Institut de Recherche Agricole pour le Développement, Centre Régional de Wakwa, Ngaoundéré, Cameroun.<br /><searchLink fieldCode="AU" term="%22Ekale+DD%22">Ekale DD</searchLink>; Institut de Recherche Agricole pour le Développement, Centre Régional de Wakwa, Ngaoundéré, Cameroun.<br /><searchLink fieldCode="AU" term="%22Mfopit+YM%22">Mfopit YM</searchLink>; Institut de Recherche Agricole pour le Développement, Centre Régional de Wakwa, Ngaoundéré, Cameroun.<br /><searchLink fieldCode="AU" term="%22Rufener+L%22">Rufener L</searchLink>; INVENesis Sarl, St-Blaise (NE), Switzerland.<br /><searchLink fieldCode="AU" term="%22Graham-Brown+J%22">Graham-Brown J</searchLink>; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tanya+VN%22">Tanya VN</searchLink>; Institut de Recherche Agricole pour le Développement, Centre Régional de Wakwa, Ngaoundéré, Cameroun.; Cameroon Academy of Sciences, Yaoundé, Cameroon.<br /><searchLink fieldCode="AU" term="%22Glenschek-Sieberth+M%22">Glenschek-Sieberth M</searchLink>; Bayer AG, Pharmaceuticals, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Kulke+D%22">Kulke D</searchLink>; Bayer Animal Health GmbH, Drug Discovery & External Innovation, Monheim am Rhein, Germany.<br /><searchLink fieldCode="AU" term="%22Makepeace+BL%22">Makepeace BL</searchLink>; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.
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  Data: <searchLink fieldCode="JN" term="%22101238921%22">PLoS pathogens</searchLink> [PLoS Pathog] 2021 Jun 02; Vol. 17 (6), pp. e1009601. <i>Date of Electronic Publication: </i>2021 Jun 02 (<i>Print Publication: </i>2021).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101238921 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1553-7374 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215537366%22">15537366 </searchLink><i>NLM ISO Abbreviation: </i>PLoS Pathog <i>Subsets: </i>MEDLINE
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