Microglial dyshomeostasis drives perineuronal net and synaptic loss in a CSF1R+/- mouse model of ALSP, which can be rescued via CSF1R inhibitors.

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Title: Microglial dyshomeostasis drives perineuronal net and synaptic loss in a CSF1R+/- mouse model of ALSP, which can be rescued via CSF1R inhibitors.
Authors: Arreola MA; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA., Soni N; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA., Crapser JD; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA., Hohsfield LA; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA., Elmore MRP; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA., Matheos DP; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA., Wood MA; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA., Swarup V; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA., Mortazavi A; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA., Green KN; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA. kngreen@uci.edu.
Source: Science advances [Sci Adv] 2021 Aug 25; Vol. 7 (35). Date of Electronic Publication: 2021 Aug 25 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE; PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Microglial dyshomeostasis drives perineuronal net and synaptic loss in a CSF1R<superscript>+/-</superscript> mouse model of ALSP, which can be rescued via CSF1R inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Arreola+MA%22">Arreola MA</searchLink>; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Soni+N%22">Soni N</searchLink>; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Crapser+JD%22">Crapser JD</searchLink>; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Hohsfield+LA%22">Hohsfield LA</searchLink>; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Elmore+MRP%22">Elmore MRP</searchLink>; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Matheos+DP%22">Matheos DP</searchLink>; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Wood+MA%22">Wood MA</searchLink>; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Swarup+V%22">Swarup V</searchLink>; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Mortazavi+A%22">Mortazavi A</searchLink>; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Green+KN%22">Green KN</searchLink>; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA. kngreen@uci.edu.
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  Data: <searchLink fieldCode="JN" term="%22101653440%22">Science advances</searchLink> [Sci Adv] 2021 Aug 25; Vol. 7 (35). <i>Date of Electronic Publication: </i>2021 Aug 25 (<i>Print Publication: </i>2021).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101653440 <i>Publication Model: </i>Electronic-Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2375-2548 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223752548%22">23752548 </searchLink><i>NLM ISO Abbreviation: </i>Sci Adv <i>Subsets: </i>MEDLINE; PubMed not MEDLINE
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        Value: 10.1126/sciadv.abg1601
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      – TitleFull: Microglial dyshomeostasis drives perineuronal net and synaptic loss in a CSF1R+/- mouse model of ALSP, which can be rescued via CSF1R inhibitors.
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              Text: 2021 Aug 25
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