Immunotherapy combinations overcome resistance to bispecific T cell engager treatment in T cell-cold solid tumors.
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| Title: | Immunotherapy combinations overcome resistance to bispecific T cell engager treatment in T cell-cold solid tumors. |
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| Authors: | Belmontes B; Amgen Research, Thousand Oaks, CA 91320, USA.; Inflammation and Oncology Therapeutic Area, Amgen, Thousand Oaks, CA 91320, USA., Sawant DV; Amgen Research, Thousand Oaks, CA 91320, USA.; Inflammation and Oncology Therapeutic Area, Amgen, South San Francisco, CA 94080, USA., Zhong W; Amgen Research, Thousand Oaks, CA 91320, USA.; Inflammation and Oncology Therapeutic Area, Amgen, South San Francisco, CA 94080, USA., Tan H; Amgen Research, Thousand Oaks, CA 91320, USA.; Inflammation and Oncology Therapeutic Area, Amgen, Thousand Oaks, CA 91320, USA., Kaul A; Amgen Research, Thousand Oaks, CA 91320, USA.; Inflammation and Oncology Therapeutic Area, Amgen, South San Francisco, CA 94080, USA., Aeffner F; Amgen Research, Thousand Oaks, CA 91320, USA.; Translational Safety and Bioanalytical Sciences, Amgen, South San Francisco, CA 94080, USA., O'Brien SA; Amgen Research, Thousand Oaks, CA 91320, USA.; Inflammation and Oncology Therapeutic Area, Amgen, South San Francisco, CA 94080, USA., Chun M; Amgen Research, Thousand Oaks, CA 91320, USA.; Inflammation and Oncology Therapeutic Area, Amgen, South San Francisco, CA 94080, USA., Noubade R; Amgen Research, Thousand Oaks, CA 91320, USA.; Inflammation and Oncology Therapeutic Area, Amgen, South San Francisco, CA 94080, USA., Eng J; Amgen Research, Thousand Oaks, CA 91320, USA.; Inflammation and Oncology Therapeutic Area, Amgen, South San Francisco, CA 94080, USA., Ma H; Amgen Research, Thousand Oaks, CA 91320, USA.; Inflammation and Oncology Therapeutic Area, Amgen, Thousand Oaks, CA 91320, USA., Muenz M; Amgen Research, Thousand Oaks, CA 91320, USA.; Amgen Research GmbH, Munich 81477, Germany., Li P; Amgen Research, Thousand Oaks, CA 91320, USA.; Therapeutic Discovery, Amgen, South San Francisco, CA 94080, USA., Alba BM; Amgen Research, Thousand Oaks, CA 91320, USA.; Therapeutic Discovery, Amgen, South San Francisco, CA 94080, USA., Thomas M; Amgen Research, Thousand Oaks, CA 91320, USA.; Therapeutic Discovery, Amgen, South San Francisco, CA 94080, USA., Cook K; Amgen Research, Thousand Oaks, CA 91320, USA.; Pharmacokinetics and Drug Metabolism, Amgen, South San Francisco, CA 94080, USA., Wang X; Amgen Research, Thousand Oaks, CA 91320, USA.; Translational Safety and Bioanalytical Sciences, Amgen, South San Francisco, CA 94080, USA., DeVoss J; Amgen Research, Thousand Oaks, CA 91320, USA.; Inflammation and Oncology Therapeutic Area, Amgen, South San Francisco, CA 94080, USA., Egen JG; Amgen Research, Thousand Oaks, CA 91320, USA. oliviern@amgen.com Jackson.egen@gmail.com.; Inflammation and Oncology Therapeutic Area, Amgen, South San Francisco, CA 94080, USA., Nolan-Stevaux O; Amgen Research, Thousand Oaks, CA 91320, USA. oliviern@amgen.com Jackson.egen@gmail.com.; Inflammation and Oncology Therapeutic Area, Amgen, South San Francisco, CA 94080, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2021 Aug 25; Vol. 13 (608). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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