Novel selective κ agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion.
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| Title: | Novel selective κ agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion. |
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| Authors: | Wei YY; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China., Ma Y; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China., Yao SY; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China., Kong LH; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China., Liu X; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China., Chai JR; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China., Chen J; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China., Li W; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China. wei-li@fudan.edu.cn., Wang YJ; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. yjwang@mail.simm.ac.cn., Shao LM; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China. limingshao@fudan.edu.cn., Liu JG; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China. jgliu@simm.ac.cn.; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. jgliu@simm.ac.cn.; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China. jgliu@simm.ac.cn. |
| Source: | Acta pharmacologica Sinica [Acta Pharmacol Sin] 2022 Jun; Vol. 43 (6), pp. 1372-1382. Date of Electronic Publication: 2021 Sep 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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