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A phase I/II dose-escalation multi-center study to evaluate the safety of infusion of natural killer cells or memory T cells as adoptive therapy in coronavirus pneumonia and/or lymphopenia: RELEASE study protocol.

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Title: A phase I/II dose-escalation multi-center study to evaluate the safety of infusion of natural killer cells or memory T cells as adoptive therapy in coronavirus pneumonia and/or lymphopenia: RELEASE study protocol.
Authors: García-García I; Clinical Pharmacology Department, University Hospital La Paz, Madrid, Spain., Guerra-García P; Clinical Pharmacology Department, University Hospital La Paz, Madrid, Spain.; Pediatric Hemato-oncology Department, University Hospital La Paz, Madrid, Spain.; Hospital La Paz Institute for Health Research, IdiPAZ, University Hospital La Paz, Madrid, Spain., Ferreras C; Hospital La Paz Institute for Health Research, IdiPAZ, University Hospital La Paz, Madrid, Spain., Borobia AM; Clinical Pharmacology Department, University Hospital La Paz, Madrid, Spain.; Hospital La Paz Institute for Health Research, IdiPAZ, University Hospital La Paz, Madrid, Spain.; Faculty of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., Carcas AJ; Clinical Pharmacology Department, University Hospital La Paz, Madrid, Spain.; Hospital La Paz Institute for Health Research, IdiPAZ, University Hospital La Paz, Madrid, Spain.; Faculty of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., Queiruga-Parada J; Clinical Pharmacology Department, University Hospital La Paz, Madrid, Spain., Vicario JL; Regional Blood Transfusion Centre, Madrid, Spain., Mirones I; Pediatric Hemato-oncology Department, University Hospital La Paz, Madrid, Spain., Solano C; Hospital Clínico Universitario de Valencia/Instituto de Investigación Sanitaria INCLIVA, Universidad de Valencia, Valencia, Spain., Eguizabal C; Research Unit, Basque Center for Blood Transfusion and Human Tissues, Osakidetza, Galdakao, Bizkaia, Spain.; Cell Therapy, Stem Cells and Tissues Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Bizkaia, Spain., Soria B; Institute of Bioengineering, Miguel Hernández University, Elche, Alicante, Spain.; Health Research Institute-ISABIAL, Alicante University Hospital, Alicante, Spain.; University Pablo de Olavide, Sevilla, Spain., Pérez-Martínez A; Pediatric Hemato-oncology Department, University Hospital La Paz, Madrid, Spain. aperezmartinez@salud.madrid.org.; Hospital La Paz Institute for Health Research, IdiPAZ, University Hospital La Paz, Madrid, Spain. aperezmartinez@salud.madrid.org.; Faculty of Medicine, Universidad Autónoma de Madrid, Madrid, Spain. aperezmartinez@salud.madrid.org.
Source: Trials [Trials] 2021 Oct 02; Vol. 22 (1), pp. 674. Date of Electronic Publication: 2021 Oct 02.
Publication Type: Clinical Trial Protocol; Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A phase I/II dose-escalation multi-center study to evaluate the safety of infusion of natural killer cells or memory T cells as adoptive therapy in coronavirus pneumonia and/or lymphopenia: RELEASE study protocol.
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  Data: <searchLink fieldCode="AU" term="%22García-García+I%22">García-García I</searchLink>; Clinical Pharmacology Department, University Hospital La Paz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Guerra-García+P%22">Guerra-García P</searchLink>; Clinical Pharmacology Department, University Hospital La Paz, Madrid, Spain.; Pediatric Hemato-oncology Department, University Hospital La Paz, Madrid, Spain.; Hospital La Paz Institute for Health Research, IdiPAZ, University Hospital La Paz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ferreras+C%22">Ferreras C</searchLink>; Hospital La Paz Institute for Health Research, IdiPAZ, University Hospital La Paz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Borobia+AM%22">Borobia AM</searchLink>; Clinical Pharmacology Department, University Hospital La Paz, Madrid, Spain.; Hospital La Paz Institute for Health Research, IdiPAZ, University Hospital La Paz, Madrid, Spain.; Faculty of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Carcas+AJ%22">Carcas AJ</searchLink>; Clinical Pharmacology Department, University Hospital La Paz, Madrid, Spain.; Hospital La Paz Institute for Health Research, IdiPAZ, University Hospital La Paz, Madrid, Spain.; Faculty of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Queiruga-Parada+J%22">Queiruga-Parada J</searchLink>; Clinical Pharmacology Department, University Hospital La Paz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Vicario+JL%22">Vicario JL</searchLink>; Regional Blood Transfusion Centre, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Mirones+I%22">Mirones I</searchLink>; Pediatric Hemato-oncology Department, University Hospital La Paz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Solano+C%22">Solano C</searchLink>; Hospital Clínico Universitario de Valencia/Instituto de Investigación Sanitaria INCLIVA, Universidad de Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Eguizabal+C%22">Eguizabal C</searchLink>; Research Unit, Basque Center for Blood Transfusion and Human Tissues, Osakidetza, Galdakao, Bizkaia, Spain.; Cell Therapy, Stem Cells and Tissues Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Bizkaia, Spain.<br /><searchLink fieldCode="AU" term="%22Soria+B%22">Soria B</searchLink>; Institute of Bioengineering, Miguel Hernández University, Elche, Alicante, Spain.; Health Research Institute-ISABIAL, Alicante University Hospital, Alicante, Spain.; University Pablo de Olavide, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez-Martínez+A%22">Pérez-Martínez A</searchLink>; Pediatric Hemato-oncology Department, University Hospital La Paz, Madrid, Spain. aperezmartinez@salud.madrid.org.; Hospital La Paz Institute for Health Research, IdiPAZ, University Hospital La Paz, Madrid, Spain. aperezmartinez@salud.madrid.org.; Faculty of Medicine, Universidad Autónoma de Madrid, Madrid, Spain. aperezmartinez@salud.madrid.org.
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  Data: <searchLink fieldCode="JN" term="%22101263253%22">Trials</searchLink> [Trials] 2021 Oct 02; Vol. 22 (1), pp. 674. <i>Date of Electronic Publication: </i>2021 Oct 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101263253 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-6215 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217456215%22">17456215 </searchLink><i>NLM ISO Abbreviation: </i>Trials <i>Subsets: </i>MEDLINE
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