Synthesis of a TNF inhibitor, flurbiprofen and an i-Pr analogue in enantioenriched forms by copper-catalyzed propargylic substitution with Grignard reagents.
Saved in:
| Title: | Synthesis of a TNF inhibitor, flurbiprofen and an i-Pr analogue in enantioenriched forms by copper-catalyzed propargylic substitution with Grignard reagents. |
|---|---|
| Authors: | Takashima Y; Department of Biomolecular Engineering, Tokyo Institute of Technology, Nagatsuta-cho 4259, Midori-ku, Yokohama 226-8501, Japan., Isogawa Y; Department of Biomolecular Engineering, Tokyo Institute of Technology, Nagatsuta-cho 4259, Midori-ku, Yokohama 226-8501, Japan., Tsuboi A; Department of Applied Chemistry, Meiji University, 1-1-1, Higashimita, Tama-ku, Kawasaki, Kanagawa 214-8571, Japan., Ogawa N; Department of Applied Chemistry, Meiji University, 1-1-1, Higashimita, Tama-ku, Kawasaki, Kanagawa 214-8571, Japan., Kobayashi Y; Department of Biomolecular Engineering, Tokyo Institute of Technology, Nagatsuta-cho 4259, Midori-ku, Yokohama 226-8501, Japan.; Organization for the Strategic Coordination of Research and Intellectual Properties, Meiji University, 1-1-1, Higashimita, Tama-ku, Kawasaki, Kanagawa 214-8571, Japan. ykobayas@bio.titech.ac.jp. |
| Source: | Organic & biomolecular chemistry [Org Biomol Chem] 2021 Nov 25; Vol. 19 (45), pp. 9906-9909. Date of Electronic Publication: 2021 Nov 25. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-0539 (Electronic) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 34734958 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Synthesis of a TNF inhibitor, flurbiprofen and an i-Pr analogue in enantioenriched forms by copper-catalyzed propargylic substitution with Grignard reagents. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Takashima+Y%22">Takashima Y</searchLink>; Department of Biomolecular Engineering, Tokyo Institute of Technology, Nagatsuta-cho 4259, Midori-ku, Yokohama 226-8501, Japan.<br /><searchLink fieldCode="AU" term="%22Isogawa+Y%22">Isogawa Y</searchLink>; Department of Biomolecular Engineering, Tokyo Institute of Technology, Nagatsuta-cho 4259, Midori-ku, Yokohama 226-8501, Japan.<br /><searchLink fieldCode="AU" term="%22Tsuboi+A%22">Tsuboi A</searchLink>; Department of Applied Chemistry, Meiji University, 1-1-1, Higashimita, Tama-ku, Kawasaki, Kanagawa 214-8571, Japan.<br /><searchLink fieldCode="AU" term="%22Ogawa+N%22">Ogawa N</searchLink>; Department of Applied Chemistry, Meiji University, 1-1-1, Higashimita, Tama-ku, Kawasaki, Kanagawa 214-8571, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+Y%22">Kobayashi Y</searchLink>; Department of Biomolecular Engineering, Tokyo Institute of Technology, Nagatsuta-cho 4259, Midori-ku, Yokohama 226-8501, Japan.; Organization for the Strategic Coordination of Research and Intellectual Properties, Meiji University, 1-1-1, Higashimita, Tama-ku, Kawasaki, Kanagawa 214-8571, Japan. ykobayas@bio.titech.ac.jp. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101154995%22">Organic & biomolecular chemistry</searchLink> [Org Biomol Chem] 2021 Nov 25; Vol. 19 (45), pp. 9906-9909. <i>Date of Electronic Publication: </i>2021 Nov 25. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Royal+Society+of+Chemistry%22">Royal Society of Chemistry </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101154995 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-0539 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214770520%22">14770520 </searchLink><i>NLM ISO Abbreviation: </i>Org Biomol Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34734958 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1039/d1ob01944a Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 9906 Titles: – TitleFull: Synthesis of a TNF inhibitor, flurbiprofen and an i-Pr analogue in enantioenriched forms by copper-catalyzed propargylic substitution with Grignard reagents. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Takashima Y – PersonEntity: Name: NameFull: Isogawa Y – PersonEntity: Name: NameFull: Tsuboi A – PersonEntity: Name: NameFull: Ogawa N – PersonEntity: Name: NameFull: Kobayashi Y IsPartOfRelationships: – BibEntity: Dates: – D: 25 M: 11 Text: 2021 Nov 25 Type: published Y: 2021 Identifiers: – Type: issn-electronic Value: 1477-0539 Numbering: – Type: volume Value: 19 – Type: issue Value: 45 Titles: – TitleFull: Organic & biomolecular chemistry Type: main |
| ResultId | 1 |
