TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion.
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| Title: | TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion. |
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| Authors: | Shakiba M; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY., Zumbo P; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY.; Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY., Espinosa-Carrasco G; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY., Menocal L; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY., Dündar F; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY.; Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY., Carson SE; Department of Biochemistry, Cell and Molecular Biology, Weill Cornell Medicine, New York, NY., Bruno EM; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY., Sanchez-Rivera FJ; Cancer Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY., Lowe SW; Cancer Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY., Camara S; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY., Koche RP; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY., Reuter VP; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY., Socci ND; Bioinformatics Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY., Whitlock B; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY., Tamzalit F; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY., Huse M; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY.; Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY., Hellmann MD; Parker Institute for Cancer Immunotherapy, San Francisco, CA.; Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY.; Weill Cornell Medical College, Cornell University, New York, NY., Wells DK; Parker Institute for Cancer Immunotherapy, San Francisco, CA., Defranoux NA; Parker Institute for Cancer Immunotherapy, San Francisco, CA., Betel D; Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY.; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY., Philip M; Department of Medicine, Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN., Schietinger A; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY.; Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY. |
| Source: | The Journal of experimental medicine [J Exp Med] 2022 Feb 07; Vol. 219 (2). Date of Electronic Publication: 2021 Dec 22. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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