Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target.
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| Title: | Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target. |
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| Authors: | Kroenke MA; Clinical Immunology, Translational Medicine, Amgen, Thousand Oaks, CA, United States., Barger TE; Translational Safety & Bioanalytical Sciences, Amgen, Thousand Oaks, CA, United States., Hu J; Translational Safety & Bioanalytical Sciences, Amgen, Thousand Oaks, CA, United States., Miller MJ; Translational Safety & Bioanalytical Sciences, Amgen, Thousand Oaks, CA, United States., Kalenian K; Process Development, Attribute Sciences, Amgen, Thousand Oaks, CA, United States., He L; Process Development, Attribute Sciences, Amgen, Thousand Oaks, CA, United States., Hsu H; Inflammation Research, Amgen, Thousand Oaks, CA, United States., Bartley Y; Global Safety, Amgen, Thousand Oaks, CA, United States., Chow VF; Clinical Pharmacology, Modeling and Simulation, Translational Medicine, Amgen, Thousand Oaks, CA, United States., Teixeira Dos Santos MC; Clinical Biomarkers and Diagnostics, Translational Medicine, Amgen, Thousand Oaks, CA, United States., Sullivan BA; Clinical Biomarkers and Diagnostics, Translational Medicine, Amgen, Thousand Oaks, CA, United States., Cheng LE; Early Development, Translational Medicine, Amgen, Thousand Oaks, CA, United States., Parnes JR; Early Development, Translational Medicine, Amgen, Thousand Oaks, CA, United States., Padaki R; Process Development, Attribute Sciences, Amgen, Thousand Oaks, CA, United States., Kuhns S; Process Development, Attribute Sciences, Amgen, Thousand Oaks, CA, United States., Mytych DT; Clinical Immunology, Translational Medicine, Amgen, Thousand Oaks, CA, United States. |
| Source: | Frontiers in immunology [Front Immunol] 2021 Dec 14; Vol. 12, pp. 782788. Date of Electronic Publication: 2021 Dec 14 (Print Publication: 2021). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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