Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function.
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| Title: | Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function. |
|---|---|
| Authors: | Hawe JS; Institute of Computational Biology, Deutsches Forschungszentrum für Gesundheit und Umwelt, Helmholtz Zentrum München, Neuherberg, Germany.; Department of Informatics, Technical University of Munich, Garching bei München, Germany., Wilson R; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany., Schmid KT; Institute of Computational Biology, Deutsches Forschungszentrum für Gesundheit und Umwelt, Helmholtz Zentrum München, Neuherberg, Germany.; Department of Informatics, Technical University of Munich, Garching bei München, Germany., Zhou L; Lee Kong Chian School of Medicine, Singapore, Singapore., Lakshmanan LN; Lee Kong Chian School of Medicine, Singapore, Singapore., Lehne BC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Kühnel B; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Wielscher M; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Yew YW; Lee Kong Chian School of Medicine, Singapore, Singapore., Baumbach C; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany., Lee DP; Genome Institute of Singapore, Singapore, Singapore., Marouli E; Centre for Genomic Health, Queen Mary University of London, London, UK.; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Bernard M; Departments of Physiology and Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.; The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Pfeiffer L; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany., Matías-García PR; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany., Autio MI; Genome Institute of Singapore, Singapore, Singapore.; Cardiovascular Research Institute, National University Health Systems, National University of Singapore, Singapore, Singapore., Bourgeois S; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Herder C; German Center for Diabetes Research (DZD), partner site Düsseldorf, Düsseldorf, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany.; Division of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany., Karhunen V; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technical University Munich, Munich, Germany., Prokisch H; Institute of Human Genetics, Technical University Munich, Munich, Germany.; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Rathmann W; German Center for Diabetes Research (DZD), partner site Düsseldorf, Düsseldorf, Germany.; Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Roden M; German Center for Diabetes Research (DZD), partner site Düsseldorf, Düsseldorf, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany.; Division of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany., Sebert S; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Department for Genomics of Common Diseases, School of Public Health, Imperial College London, London, UK., Shin J; Departments of Physiology and Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.; The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Strauch K; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Southall, UK., Tan WLW; Genome Institute of Singapore, Singapore, Singapore., Hauck SM; Research Unit Protein Science, Helmholtz Zentrum München, German Research Centre for Environmental Health, Munich, Germany., Merl-Pham J; Research Unit Protein Science, Helmholtz Zentrum München, German Research Centre for Environmental Health, Munich, Germany., Grallert H; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany., Barbosa EGV; Institute of Computational Biology, Deutsches Forschungszentrum für Gesundheit und Umwelt, Helmholtz Zentrum München, Neuherberg, Germany., Illig T; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.; Institute for Human Genetics, Hannover Medical School, Hannover, Germany., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany.; German Research Center for Cardiovascular Disease (DZHK), partner site Munich Heart Alliance, Hannover, Germany., Paus T; Centre Hospitalier Universitaire Sainte-Justine, University of Montreal, Montreal, Canada., Pausova Z; Departments of Physiology and Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.; The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Deloukas P; Centre for Genomic Health, Queen Mary University of London, London, UK.; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Foo RSY; Genome Institute of Singapore, Singapore, Singapore.; Cardiovascular Research Institute, National University Health Systems, National University of Singapore, Singapore, Singapore., Jarvelin MR; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Kooner JS; National Heart and Lung Institute, Imperial College London, London, UK. j.kooner@ic.ac.uk., Loh M; Lee Kong Chian School of Medicine, Singapore, Singapore. marie.loh@ntu.edu.sg.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK. marie.loh@ntu.edu.sg., Heinig M; Institute of Computational Biology, Deutsches Forschungszentrum für Gesundheit und Umwelt, Helmholtz Zentrum München, Neuherberg, Germany. matthias.heinig@helmholtz-muenchen.de.; Department of Informatics, Technical University of Munich, Garching bei München, Germany. matthias.heinig@helmholtz-muenchen.de., Gieger C; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. christian.gieger@helmholtz-muenchen.de.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany. christian.gieger@helmholtz-muenchen.de., Waldenberger M; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. waldenberger@helmholtz-muenchen.de.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany. waldenberger@helmholtz-muenchen.de.; German Research Center for Cardiovascular Disease (DZHK), partner site Munich Heart Alliance, Hannover, Germany. waldenberger@helmholtz-muenchen.de., Chambers JC; Lee Kong Chian School of Medicine, Singapore, Singapore. john.chambers@ic.ac.uk.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK. john.chambers@ic.ac.uk. |
| Corporate Authors: | MuTHER Consortium |
| Source: | Nature genetics [Nat Genet] 2022 Jan; Vol. 54 (1), pp. 18-29. Date of Electronic Publication: 2022 Jan 03. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 34980917 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hawe+JS%22">Hawe JS</searchLink>; Institute of Computational Biology, Deutsches Forschungszentrum für Gesundheit und Umwelt, Helmholtz Zentrum München, Neuherberg, Germany.; Department of Informatics, Technical University of Munich, Garching bei München, Germany.<br /><searchLink fieldCode="AU" term="%22Wilson+R%22">Wilson R</searchLink>; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmid+KT%22">Schmid KT</searchLink>; Institute of Computational Biology, Deutsches Forschungszentrum für Gesundheit und Umwelt, Helmholtz Zentrum München, Neuherberg, Germany.; Department of Informatics, Technical University of Munich, Garching bei München, Germany.<br /><searchLink fieldCode="AU" term="%22Zhou+L%22">Zhou L</searchLink>; Lee Kong Chian School of Medicine, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lakshmanan+LN%22">Lakshmanan LN</searchLink>; Lee Kong Chian School of Medicine, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lehne+BC%22">Lehne BC</searchLink>; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kühnel+B%22">Kühnel B</searchLink>; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Scott+WR%22">Scott WR</searchLink>; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Wielscher+M%22">Wielscher M</searchLink>; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Yew+YW%22">Yew YW</searchLink>; Lee Kong Chian School of Medicine, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Baumbach+C%22">Baumbach C</searchLink>; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lee+DP%22">Lee DP</searchLink>; Genome Institute of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Marouli+E%22">Marouli E</searchLink>; Centre for Genomic Health, Queen Mary University of London, London, UK.; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Bernard+M%22">Bernard M</searchLink>; 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Division of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Sebert+S%22">Sebert S</searchLink>; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Department for Genomics of Common Diseases, School of Public Health, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Shin+J%22">Shin J</searchLink>; Departments of Physiology and Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.; The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Strauch+K%22">Strauch K</searchLink>; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; 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German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Barbosa+EGV%22">Barbosa EGV</searchLink>; Institute of Computational Biology, Deutsches Forschungszentrum für Gesundheit und Umwelt, Helmholtz Zentrum München, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Illig+T%22">Illig T</searchLink>; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.; Institute for Human Genetics, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Peters+A%22">Peters A</searchLink>; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany.; German Research Center for Cardiovascular Disease (DZHK), partner site Munich Heart Alliance, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Paus+T%22">Paus T</searchLink>; Centre Hospitalier Universitaire Sainte-Justine, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Pausova+Z%22">Pausova Z</searchLink>; Departments of Physiology and Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.; The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Deloukas+P%22">Deloukas P</searchLink>; Centre for Genomic Health, Queen Mary University of London, London, UK.; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Foo+RSY%22">Foo RSY</searchLink>; Genome Institute of Singapore, Singapore, Singapore.; Cardiovascular Research Institute, National University Health Systems, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Jarvelin+MR%22">Jarvelin MR</searchLink>; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; 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Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. christian.gieger@helmholtz-muenchen.de.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany. christian.gieger@helmholtz-muenchen.de.<br /><searchLink fieldCode="AU" term="%22Waldenberger+M%22">Waldenberger M</searchLink>; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. waldenberger@helmholtz-muenchen.de.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany. waldenberger@helmholtz-muenchen.de.; German Research Center for Cardiovascular Disease (DZHK), partner site Munich Heart Alliance, Hannover, Germany. waldenberger@helmholtz-muenchen.de.<br /><searchLink fieldCode="AU" term="%22Chambers+JC%22">Chambers JC</searchLink>; Lee Kong Chian School of Medicine, Singapore, Singapore. john.chambers@ic.ac.uk.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK. john.chambers@ic.ac.uk. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22MuTHER+Consortium%22">MuTHER Consortium</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2022 Jan; Vol. 54 (1), pp. 18-29. <i>Date of Electronic Publication: </i>2022 Jan 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Co%22">Nature Pub. Co </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9216904 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1546-1718 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210614036%22">10614036 </searchLink><i>NLM ISO Abbreviation: </i>Nat Genet <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41588-021-00969-x Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 18 Titles: – TitleFull: Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hawe JS – PersonEntity: Name: NameFull: Wilson R – PersonEntity: Name: NameFull: Schmid KT – PersonEntity: Name: NameFull: Zhou L – PersonEntity: Name: NameFull: Lakshmanan LN – PersonEntity: Name: NameFull: Lehne BC – PersonEntity: Name: NameFull: Kühnel B – PersonEntity: Name: NameFull: Scott WR – PersonEntity: Name: NameFull: Wielscher M – PersonEntity: Name: NameFull: Yew YW – PersonEntity: Name: NameFull: Baumbach C – PersonEntity: Name: NameFull: Lee DP – PersonEntity: Name: NameFull: Marouli E – PersonEntity: Name: NameFull: Bernard M – PersonEntity: Name: NameFull: Pfeiffer L – PersonEntity: Name: NameFull: Matías-García PR – PersonEntity: Name: NameFull: Autio MI – PersonEntity: Name: NameFull: Bourgeois S – PersonEntity: Name: NameFull: Herder C – PersonEntity: Name: NameFull: Karhunen V – PersonEntity: Name: NameFull: Meitinger T – PersonEntity: Name: NameFull: Prokisch H – PersonEntity: Name: NameFull: Rathmann W – PersonEntity: Name: NameFull: Roden M – PersonEntity: Name: NameFull: Sebert S – PersonEntity: Name: NameFull: Shin J – PersonEntity: Name: NameFull: Strauch K – PersonEntity: Name: NameFull: Zhang W – PersonEntity: Name: NameFull: Tan WLW – PersonEntity: Name: NameFull: Hauck SM – PersonEntity: Name: NameFull: Merl-Pham J – PersonEntity: Name: NameFull: Grallert H – PersonEntity: Name: NameFull: Barbosa EGV – PersonEntity: Name: NameFull: Illig T – PersonEntity: Name: NameFull: Peters A – PersonEntity: Name: NameFull: Paus T – PersonEntity: Name: NameFull: Pausova Z – PersonEntity: Name: NameFull: Deloukas P – PersonEntity: Name: NameFull: Foo RSY – PersonEntity: Name: NameFull: Jarvelin MR – PersonEntity: Name: NameFull: Kooner JS – PersonEntity: Name: NameFull: Loh M – PersonEntity: Name: NameFull: Heinig M – PersonEntity: Name: NameFull: Gieger C – PersonEntity: Name: NameFull: Waldenberger M – PersonEntity: Name: NameFull: Chambers JC IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: 2022 Jan Type: published Y: 2022 Identifiers: – Type: issn-electronic Value: 1546-1718 Numbering: – Type: volume Value: 54 – Type: issue Value: 1 Titles: – TitleFull: Nature genetics Type: main |
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