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Phase I Trial of Definitive Concurrent Chemoradiotherapy and Trametinib for KRAS-Mutated Non-Small Cell Lung Cancer.

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Title: Phase I Trial of Definitive Concurrent Chemoradiotherapy and Trametinib for KRAS-Mutated Non-Small Cell Lung Cancer.
Authors: Lin SH; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA. Electronic address: shlin@mdanderson.org., Lin HY; Department of Biostatistics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Verma V; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Xu-Welliver M; Department of Radiation Oncology, Ohio State University, Columbus, OH, USA., Thall PF; Department of Biostatistics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Yao L; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Kim PY; Department of Cardiology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Gombos DS; Department of Ophthalmology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Kawedia JD; Clinical Pharmacy Research, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Komaki R; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Gomez DR; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Nguyen QN; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., O'Reilly MS; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Lu C; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Fossella FV; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Skoulidis F; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Zhang J; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Tsao AS; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Heymach JV; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Blumenschein GR; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Source: Cancer treatment and research communications [Cancer Treat Res Commun] 2022; Vol. 30, pp. 100514. Date of Electronic Publication: 2022 Jan 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101694651 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2468-2942 (Electronic) Linking ISSN: 24682942 NLM ISO Abbreviation: Cancer Treat Res Commun Subsets: MEDLINE; PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Phase I Trial of Definitive Concurrent Chemoradiotherapy and Trametinib for KRAS-Mutated Non-Small Cell Lung Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Lin+SH%22">Lin SH</searchLink>; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA. Electronic address: shlin@mdanderson.org.<br /><searchLink fieldCode="AU" term="%22Lin+HY%22">Lin HY</searchLink>; Department of Biostatistics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Verma+V%22">Verma V</searchLink>; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Xu-Welliver+M%22">Xu-Welliver M</searchLink>; Department of Radiation Oncology, Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Thall+PF%22">Thall PF</searchLink>; Department of Biostatistics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Yao+L%22">Yao L</searchLink>; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kim+PY%22">Kim PY</searchLink>; Department of Cardiology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Gombos+DS%22">Gombos DS</searchLink>; Department of Ophthalmology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kawedia+JD%22">Kawedia JD</searchLink>; Clinical Pharmacy Research, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Komaki+R%22">Komaki R</searchLink>; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Gomez+DR%22">Gomez DR</searchLink>; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+QN%22">Nguyen QN</searchLink>; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22O'Reilly+MS%22">O'Reilly MS</searchLink>; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lu+C%22">Lu C</searchLink>; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Fossella+FV%22">Fossella FV</searchLink>; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Skoulidis+F%22">Skoulidis F</searchLink>; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Tsao+AS%22">Tsao AS</searchLink>; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Heymach+JV%22">Heymach JV</searchLink>; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Blumenschein+GR%22">Blumenschein GR</searchLink>; Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
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  Data: <searchLink fieldCode="JN" term="%22101694651%22">Cancer treatment and research communications</searchLink> [Cancer Treat Res Commun] 2022; Vol. 30, pp. 100514. <i>Date of Electronic Publication: </i>2022 Jan 07.
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