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Enrichment of the exocytosis protein STX4 in skeletal muscle remediates peripheral insulin resistance and alters mitochondrial dynamics via Drp1.

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Title: Enrichment of the exocytosis protein STX4 in skeletal muscle remediates peripheral insulin resistance and alters mitochondrial dynamics via Drp1.
Authors: Merz KE; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.; Irell and Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA, USA.; Amgen, Thousand Oaks, CA, USA., Hwang J; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA., Zhou C; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA., Veluthakal R; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA., McCown EM; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA., Hamilton A; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA., Oh E; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA., Dai W; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA., Fueger PT; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.; Comprehensive Metabolic Phenotyping Core, Beckman Research Institute of City of Hope, Duarte, CA, USA., Jiang L; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA., Huss JM; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.; Washington University School of Medicine, St. Louis, MO, USA., Thurmond DC; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA. dthurmond@coh.org.
Source: Nature communications [Nat Commun] 2022 Jan 20; Vol. 13 (1), pp. 424. Date of Electronic Publication: 2022 Jan 20.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Enrichment of the exocytosis protein STX4 in skeletal muscle remediates peripheral insulin resistance and alters mitochondrial dynamics via Drp1.
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  Data: <searchLink fieldCode="AU" term="%22Merz+KE%22">Merz KE</searchLink>; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.; Irell and Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA, USA.; Amgen, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hwang+J%22">Hwang J</searchLink>; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+C%22">Zhou C</searchLink>; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Veluthakal+R%22">Veluthakal R</searchLink>; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22McCown+EM%22">McCown EM</searchLink>; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hamilton+A%22">Hamilton A</searchLink>; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Oh+E%22">Oh E</searchLink>; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Dai+W%22">Dai W</searchLink>; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Fueger+PT%22">Fueger PT</searchLink>; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.; Comprehensive Metabolic Phenotyping Core, Beckman Research Institute of City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+L%22">Jiang L</searchLink>; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Huss+JM%22">Huss JM</searchLink>; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA.; Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Thurmond+DC%22">Thurmond DC</searchLink>; Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA, USA. dthurmond@coh.org.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Jan 20; Vol. 13 (1), pp. 424. <i>Date of Electronic Publication: </i>2022 Jan 20.
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