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Application of an organotypic ocular perfusion model to assess intravitreal drug distribution in human and animal eyes.

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Title: Application of an organotypic ocular perfusion model to assess intravitreal drug distribution in human and animal eyes.
Authors: Chan D; Donald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada., Won GJ; Donald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada., Read AT; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, Georgia, USA., Ethier CR; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, Georgia, USA., Thackaberry E; Safety Assessment, Genentech Inc., San Francisco, CA, USA., Crowell SR; Preclinical and Translational Pharmacokinetics and Pharmacodynamics (PTPK) Genentech Inc., San Francisco, CA, USA., Booler H; Safety Assessment, Genentech Inc., San Francisco, CA, USA., Bantseev V; Safety Assessment, Genentech Inc., San Francisco, CA, USA., Sivak JM; Donald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Source: Journal of the Royal Society, Interface [J R Soc Interface] 2022 Jan; Vol. 19 (186), pp. 20210734. Date of Electronic Publication: 2022 Jan 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Royal Society Country of Publication: England NLM ID: 101217269 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-5662 (Electronic) Linking ISSN: 17425662 NLM ISO Abbreviation: J R Soc Interface Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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PreciseRelevancyScore: 0
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  Data: Application of an organotypic ocular perfusion model to assess intravitreal drug distribution in human and animal eyes.
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  Data: <searchLink fieldCode="AU" term="%22Chan+D%22">Chan D</searchLink>; Donald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Won+GJ%22">Won GJ</searchLink>; Donald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Read+AT%22">Read AT</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Ethier+CR%22">Ethier CR</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Thackaberry+E%22">Thackaberry E</searchLink>; Safety Assessment, Genentech Inc., San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Crowell+SR%22">Crowell SR</searchLink>; Preclinical and Translational Pharmacokinetics and Pharmacodynamics (PTPK) Genentech Inc., San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Booler+H%22">Booler H</searchLink>; Safety Assessment, Genentech Inc., San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bantseev+V%22">Bantseev V</searchLink>; Safety Assessment, Genentech Inc., San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sivak+JM%22">Sivak JM</searchLink>; Donald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101217269%22">Journal of the Royal Society, Interface</searchLink> [J R Soc Interface] 2022 Jan; Vol. 19 (186), pp. 20210734. <i>Date of Electronic Publication: </i>2022 Jan 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Royal+Society%22">Royal Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101217269 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1742-5662 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217425662%22">17425662 </searchLink><i>NLM ISO Abbreviation: </i>J R Soc Interface <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1098/rsif.2021.0734
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      – Code: eng
        Text: English
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        StartPage: 20210734
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      – TitleFull: Application of an organotypic ocular perfusion model to assess intravitreal drug distribution in human and animal eyes.
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            NameFull: Chan D
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            NameFull: Won GJ
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            – D: 01
              M: 01
              Text: 2022 Jan
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