Application of an organotypic ocular perfusion model to assess intravitreal drug distribution in human and animal eyes.
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| Title: | Application of an organotypic ocular perfusion model to assess intravitreal drug distribution in human and animal eyes. |
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| Authors: | Chan D; Donald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada., Won GJ; Donald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada., Read AT; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, Georgia, USA., Ethier CR; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, Georgia, USA., Thackaberry E; Safety Assessment, Genentech Inc., San Francisco, CA, USA., Crowell SR; Preclinical and Translational Pharmacokinetics and Pharmacodynamics (PTPK) Genentech Inc., San Francisco, CA, USA., Booler H; Safety Assessment, Genentech Inc., San Francisco, CA, USA., Bantseev V; Safety Assessment, Genentech Inc., San Francisco, CA, USA., Sivak JM; Donald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. |
| Source: | Journal of the Royal Society, Interface [J R Soc Interface] 2022 Jan; Vol. 19 (186), pp. 20210734. Date of Electronic Publication: 2022 Jan 26. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Royal Society Country of Publication: England NLM ID: 101217269 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-5662 (Electronic) Linking ISSN: 17425662 NLM ISO Abbreviation: J R Soc Interface Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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