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Target 2035 - update on the quest for a probe for every protein.

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Title: Target 2035 - update on the quest for a probe for every protein.
Authors: Müller S; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt Frankfurt 60438 Germany.; Structural Genomics Consortium, BMLS, Goethe University Frankfurt Frankfurt 60438 Germany susanne.mueller-knapp@bmls.de., Ackloo S; Structural Genomics Consortium, University of Toronto Toronto Ontario M5G 1L7 Canada Cheryl.Arrowsmith@uhnresearch.ca., Al Chawaf A; University of Toronto Toronto Ontario M5G 1L7 Canada., Al-Lazikani B; Department of Data Science, The Institute of Cancer Research London SM2 5NG UK.; CRUK ICR/Imperial Convergence Science Centre London SM2 5NG UK., Antolin A; Department of Data Science, The Institute of Cancer Research London SM2 5NG UK.; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research London SM2 5NG UK., Baell JB; Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia.; School of Pharmaceutical Sciences, Nanjing Tech University No. 30 South Puzhu Road Nanjing 211816 People's Republic of China., Beck H; Research and Development, Bayer AG, Pharmaceuticals 42103 Wuppertal Germany., Beedie S; Centre for Medicines Discovery, University of Oxford Old Road Campus Research Building, Roosevelt Drive Oxford OX3 7DQ UK., Betz UAK; Merck KGaA Darmstadt Germany., Bezerra GA; Centre for Medicines Discovery, University of Oxford Old Road Campus Research Building, Roosevelt Drive Oxford OX3 7DQ UK., Brennan PE; Alzheimer's Research UK Oxford Drug Discovery Institute, Centre for Medicines Discovery, University of Oxford Oxford OX3 7FZ UK., Brown D; Institut Recherches de Servier 125 Chemin de Ronde 78290 Croissy France., Brown PJ; Structural Genomics Consortium, University of Toronto Toronto Ontario M5G 1L7 Canada Cheryl.Arrowsmith@uhnresearch.ca., Bullock AN; Centre for Medicines Discovery, University of Oxford Old Road Campus Research Building, Roosevelt Drive Oxford OX3 7DQ UK., Carter AJ; Discovery Research, Boehringer Ingelheim 55216 Ingelheim am Rhein Germany., Chaikuad A; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt Frankfurt 60438 Germany.; Structural Genomics Consortium, BMLS, Goethe University Frankfurt Frankfurt 60438 Germany susanne.mueller-knapp@bmls.de., Chaineau M; Early Drug Discovery Unit (EDDU), Montreal Neurological Institute-Hospital, McGill University Montreal QC Canada., Ciulli A; School of Life Sciences, Division of Biological Chemistry and Drug Discovery, University of Dundee James Black Centre Dundee UK., Collins I; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research London SM2 5NG UK., Dreher J; Research and Development, Bayer AG, Pharmaceuticals 42103 Wuppertal Germany., Drewry D; Structural Genomics Consortium, UNC Eshelman School of Pharmacy Chapel Hill NC USA.; Lineberger Comprehensive Cancer Center, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA., Edfeldt K; Structural Genomics Consortium, Department of Medicine, Karolinska University Hospital and Karolinska Institutet Stockholm Sweden., Edwards AM; Structural Genomics Consortium, University of Toronto Toronto Ontario M5G 1L7 Canada Cheryl.Arrowsmith@uhnresearch.ca., Egner U; Nuvisan Innovation Campus Berlin GmbH Müllerstraße 178 13353 Berlin Germany., Frye SV; Lineberger Comprehensive Cancer Center, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA.; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA., Fuchs SM; Institute for Protein Innovation Boston MA USA., Hall MD; National Center for Advancing Translational Sciences, National Institutes of Health Rockville Maryland 20850 USA., Hartung IV; Medicinal Chemistry, Global R&D, Merck Healthcare KGaA Frankfurter Straße 250 64293 Darmstadt Germany., Hillisch A; Research and Development, Bayer AG, Pharmaceuticals 42103 Wuppertal Germany., Hitchcock SH; Takeda California 9625 Towne Centre Drive San Diego California 92121 USA., Homan E; Science for Life Laboratory, Department of Oncology-Pathology Karolinska Institutet Stockholm Sweden., Kannan N; Institute of Bioinformatics and Department of Biochemistry and Molecular Biology, University of Georgia Athens GA USA., Kiefer JR; Genentech, Inc. 1 DNA Way South San Francisco California 94080 USA., Knapp S; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt Frankfurt 60438 Germany.; Structural Genomics Consortium, BMLS, Goethe University Frankfurt Frankfurt 60438 Germany susanne.mueller-knapp@bmls.de., Kostic M; Department of Cancer Biology and Chemical Biology Program, Dana-Farber Cancer Institute 450 Brookline Ave Boston MA 02215 USA., Kubicek S; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Vienna Austria., Leach AR; European Molecular Biology Laboratory, European Bioinformatics Institute Wellcome Genome Campus, Hinxton Cambridgeshire CB10 1SD UK., Lindemann S; Strategic Innovation, Global R&D, Merck Healthcare KGaA Frankfurter Straße 250 64293 Darmstadt Germany., Marsden BD; Centre for Medicines Discovery, University of Oxford Old Road Campus Research Building, Roosevelt Drive Oxford OX3 7DQ UK.; Kennedy Institute of Rheumatology, NDORMS, University of Oxford UK., Matsui H; Neuroscience Drug Discovery Unit, Research, Takeda Pharmaceutical Company Limited Fujisawa Kanagawa Japan., Meier JL; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health Frederick MD USA., Merk D; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt Frankfurt 60438 Germany.; LMU Munich, Department of Pharmacy, Chair of Pharmaceutical and Medicinal Chemistry 81377 Munich Germany., Michel M; Science for Life Laboratory, Department of Oncology-Pathology Karolinska Institutet Stockholm Sweden., Morgan MR; Structural Genomics Consortium, University of Toronto Toronto Ontario M5G 1L7 Canada Cheryl.Arrowsmith@uhnresearch.ca., Mueller-Fahrnow A; Nuvisan Innovation Campus Berlin GmbH Müllerstraße 178 13353 Berlin Germany., Owen DR; Discovery Network Group, Pfizer Medicine Design Cambridge MA 02139 USA., Perry BG; Drugs for Neglected Diseases initiative 15 Chemin Camille Vidart Geneva 1202 Switzerland., Rosenberg SH; AbbVie North Chicago Illinois USA., Saikatendu KS; Global Research Externalization, Takeda California, Inc. 9625 Towne Center Drive San Diego CA 92121 USA., Schapira M; Structural Genomics Consortium, University of Toronto Toronto Ontario M5G 1L7 Canada Cheryl.Arrowsmith@uhnresearch.ca.; Department of Pharmacology & Toxicology, University of Toronto Toronto Ontario M5S 1A8 Canada., Scholten C; Research and Development, Bayer AG, Pharmaceuticals 13353 Berlin Germany., Sharma S; Structural & Protein Sciences, Discovery Sciences, Janssen Research & Development 1400 McKean Rd Spring House PA 19477 USA., Simeonov A; National Center for Advancing Translational Sciences, National Institutes of Health Rockville Maryland 20850 USA., Sundström M; Division of Rheumatology, Department of Medicine Solna, Karolinska University Hospital and Karolinska Institutet Stockholm Sweden., Superti-Furga G; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Vienna Austria.; Center for Physiology and Pharmacology, Medical University of Vienna Vienna Austria., Todd MH; School of Pharmacy, University College London London WC1N 1AX UK., Tredup C; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt Frankfurt 60438 Germany.; Structural Genomics Consortium, BMLS, Goethe University Frankfurt Frankfurt 60438 Germany susanne.mueller-knapp@bmls.de., Vedadi M; Structural Genomics Consortium, University of Toronto Toronto Ontario M5G 1L7 Canada Cheryl.Arrowsmith@uhnresearch.ca.; Department of Pharmacology & Toxicology, University of Toronto Toronto Ontario M5S 1A8 Canada., von Delft F; Centre for Medicines Discovery, University of Oxford Old Road Campus Research Building, Roosevelt Drive Oxford OX3 7DQ UK.; Diamond Light Source Ltd Harwell Science and Innovation Campus Didcot OX11 0QX UK.; Department of Biochemistry, University of Johannesburg Auckland Park 2006 South Africa.; Research Complex at Harwell Harwell Science and Innovation Campus Didcot OX11 0FA UK., Willson TM; Lineberger Comprehensive Cancer Center, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA., Winter GE; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Vienna Austria., Workman P; CRUK ICR/Imperial Convergence Science Centre London SM2 5NG UK.; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research London SM2 5NG UK., Arrowsmith CH; Structural Genomics Consortium, University of Toronto Toronto Ontario M5G 1L7 Canada Cheryl.Arrowsmith@uhnresearch.ca.; Princess Margaret Cancer Centre Toronto Ontario M5G 1L7 Canada.
Source: RSC medicinal chemistry [RSC Med Chem] 2021 Dec 03; Vol. 13 (1), pp. 13-21. Date of Electronic Publication: 2021 Dec 03 (Print Publication: 2022).
Publication Type: Editorial
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101759460 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8682 (Electronic) Linking ISSN: 26328682 NLM ISO Abbreviation: RSC Med Chem Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="JN" term="%22101759460%22">RSC medicinal chemistry</searchLink> [RSC Med Chem] 2021 Dec 03; Vol. 13 (1), pp. 13-21. <i>Date of Electronic Publication: </i>2021 Dec 03 (<i>Print Publication: </i>2022).
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      – PersonEntity:
          Name:
            NameFull: Kostic M
      – PersonEntity:
          Name:
            NameFull: Kubicek S
      – PersonEntity:
          Name:
            NameFull: Leach AR
      – PersonEntity:
          Name:
            NameFull: Lindemann S
      – PersonEntity:
          Name:
            NameFull: Marsden BD
      – PersonEntity:
          Name:
            NameFull: Matsui H
      – PersonEntity:
          Name:
            NameFull: Meier JL
      – PersonEntity:
          Name:
            NameFull: Merk D
      – PersonEntity:
          Name:
            NameFull: Michel M
      – PersonEntity:
          Name:
            NameFull: Morgan MR
      – PersonEntity:
          Name:
            NameFull: Mueller-Fahrnow A
      – PersonEntity:
          Name:
            NameFull: Owen DR
      – PersonEntity:
          Name:
            NameFull: Perry BG
      – PersonEntity:
          Name:
            NameFull: Rosenberg SH
      – PersonEntity:
          Name:
            NameFull: Saikatendu KS
      – PersonEntity:
          Name:
            NameFull: Schapira M
      – PersonEntity:
          Name:
            NameFull: Scholten C
      – PersonEntity:
          Name:
            NameFull: Sharma S
      – PersonEntity:
          Name:
            NameFull: Simeonov A
      – PersonEntity:
          Name:
            NameFull: Sundström M
      – PersonEntity:
          Name:
            NameFull: Superti-Furga G
      – PersonEntity:
          Name:
            NameFull: Todd MH
      – PersonEntity:
          Name:
            NameFull: Tredup C
      – PersonEntity:
          Name:
            NameFull: Vedadi M
      – PersonEntity:
          Name:
            NameFull: von Delft F
      – PersonEntity:
          Name:
            NameFull: Willson TM
      – PersonEntity:
          Name:
            NameFull: Winter GE
      – PersonEntity:
          Name:
            NameFull: Workman P
      – PersonEntity:
          Name:
            NameFull: Arrowsmith CH
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 03
              M: 12
              Text: 2021 Dec 03
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 2632-8682
          Numbering:
            – Type: volume
              Value: 13
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: RSC medicinal chemistry
              Type: main
ResultId 1