Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium.

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Title: Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium.
Authors: Higa T; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan., Okita Y; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan., Matsumoto A; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan., Nakayama S; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan., Oka T; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan., Sugahara O; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan., Koga D; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan., Takeishi S; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA., Nakatsumi H; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.; Department of Molecular Biology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Aichi, 467-8603, Japan., Hosen N; Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan., Robine S; UMR 144, Institut Curie, 75248 Paris Cedex 05, Paris, France., Taketo MM; Kyoto University Hospital-iACT (Colon Cancer Project), Graduate School of Medicine, Kyoto University, Kyoto, 606-8501, Japan., Sato T; Department of Organoid Medicine, Keio University School of Medicine, Tokyo, 160-8582, Japan., Nakayama KI; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan. nakayak1@bioreg.kyushu-u.ac.jp.
Source: Nature communications [Nat Commun] 2022 Mar 21; Vol. 13 (1), pp. 1500. Date of Electronic Publication: 2022 Mar 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium.
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  Data: <searchLink fieldCode="AU" term="%22Higa+T%22">Higa T</searchLink>; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.<br /><searchLink fieldCode="AU" term="%22Okita+Y%22">Okita Y</searchLink>; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.<br /><searchLink fieldCode="AU" term="%22Matsumoto+A%22">Matsumoto A</searchLink>; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.<br /><searchLink fieldCode="AU" term="%22Nakayama+S%22">Nakayama S</searchLink>; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.<br /><searchLink fieldCode="AU" term="%22Oka+T%22">Oka T</searchLink>; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.<br /><searchLink fieldCode="AU" term="%22Sugahara+O%22">Sugahara O</searchLink>; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.<br /><searchLink fieldCode="AU" term="%22Koga+D%22">Koga D</searchLink>; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.<br /><searchLink fieldCode="AU" term="%22Takeishi+S%22">Takeishi S</searchLink>; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.<br /><searchLink fieldCode="AU" term="%22Nakatsumi+H%22">Nakatsumi H</searchLink>; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.; Department of Molecular Biology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Aichi, 467-8603, Japan.<br /><searchLink fieldCode="AU" term="%22Hosen+N%22">Hosen N</searchLink>; Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Robine+S%22">Robine S</searchLink>; UMR 144, Institut Curie, 75248 Paris Cedex 05, Paris, France.<br /><searchLink fieldCode="AU" term="%22Taketo+MM%22">Taketo MM</searchLink>; Kyoto University Hospital-iACT (Colon Cancer Project), Graduate School of Medicine, Kyoto University, Kyoto, 606-8501, Japan.<br /><searchLink fieldCode="AU" term="%22Sato+T%22">Sato T</searchLink>; Department of Organoid Medicine, Keio University School of Medicine, Tokyo, 160-8582, Japan.<br /><searchLink fieldCode="AU" term="%22Nakayama+KI%22">Nakayama KI</searchLink>; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan. nakayak1@bioreg.kyushu-u.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Mar 21; Vol. 13 (1), pp. 1500. <i>Date of Electronic Publication: </i>2022 Mar 21.
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