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Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors.

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Title: Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors.
Authors: Horton JR; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Pathuri S; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Wong K; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA., Ren R; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Rueda L; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA., Fosbenner DT; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA., Heerding DA; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA., McCabe MT; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA., Pappalardi MB; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA., Zhang X; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., King BW; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA. Electronic address: bryan.w.king@gsk.com., Cheng X; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: xcheng5@mdanderson.org.
Source: Structure (London, England : 1993) [Structure] 2022 Jun 02; Vol. 30 (6), pp. 793-802.e5. Date of Electronic Publication: 2022 Apr 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Horton+JR%22">Horton JR</searchLink>; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Pathuri+S%22">Pathuri S</searchLink>; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Wong+K%22">Wong K</searchLink>; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.<br /><searchLink fieldCode="AU" term="%22Ren+R%22">Ren R</searchLink>; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Rueda+L%22">Rueda L</searchLink>; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.<br /><searchLink fieldCode="AU" term="%22Fosbenner+DT%22">Fosbenner DT</searchLink>; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.<br /><searchLink fieldCode="AU" term="%22Heerding+DA%22">Heerding DA</searchLink>; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.<br /><searchLink fieldCode="AU" term="%22McCabe+MT%22">McCabe MT</searchLink>; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.<br /><searchLink fieldCode="AU" term="%22Pappalardi+MB%22">Pappalardi MB</searchLink>; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22King+BW%22">King BW</searchLink>; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA. Electronic address: bryan.w.king@gsk.com.<br /><searchLink fieldCode="AU" term="%22Cheng+X%22">Cheng X</searchLink>; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: xcheng5@mdanderson.org.
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  Data: <searchLink fieldCode="JN" term="%22101087697%22">Structure (London, England : 1993)</searchLink> [Structure] 2022 Jun 02; Vol. 30 (6), pp. 793-802.e5. <i>Date of Electronic Publication: </i>2022 Apr 07.
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