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Notch1-CD22-Dependent Immune Dysregulation in the SARS-CoV2-Associated Multisystem Inflammatory Syndrome in Children.

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Title: Notch1-CD22-Dependent Immune Dysregulation in the SARS-CoV2-Associated Multisystem Inflammatory Syndrome in Children.
Authors: Chatila TA; Boston Children's Hospital - Harvard Medical School., Benamar M; INSERM., Chen Q; Division of Immunology, Boston Children's Hospital, Boston, Massachusetts, USA; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Chou J; Childrens Hospital Boston/Harvard Medical School., Julé A; Division of Immunology, Boston Children's Hospital, Boston, Massachusetts, USA; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Boudra R; Harvard Medical School., Contini P; University of Genoa., Crestani E; Boston Children's Hospital - Harvard Medical School., Wang M; 1Division of Immunology, Boston Children's Hospital, Boston, Massachusetts, USA; 2Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Fong J; Boston Children's Hospital., Lai P; Massachusetts General Hospital, Harvard Medical School., Rockwitz S; The Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, USA., Lee P; Boston Children's Hospital., Chan TMF; 1Division of Immunology, Boston Children's Hospital, Boston, Massachusetts, USA; 2Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Altun EZ; Ministry of Healthy, Marmara University Education and Training Hospital, Department of Pediatrics, Istanbul, Turkey., Kepenekli E; Marmara University, Faculty of Medicine, Division of Pediatric Infectious Diseases, Istanbul, Turkey., Karakoc-Aydiner E; Marmara University, School of Medicine, Department of Pediatrics, Division of Allergy and Immunology, Istanbul., Ozen A; Marmara University., Boran P; Marmara University, Faculty of Medicine, Division of Social Pediatrics, Istanbul, Turkey., Aygun F; Department of Pediatric Intensive Care, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey., Onal P; Department of Pediatric Infectious Diseases, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey., Sakalli AAK; Department of Pediatric Pulmonology, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey., Cokugras H; Department of Pediatric Infectious Diseases, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey. Department of Pediatric Pulmonology, Cerrahp., Gelmez M; Istanbul University., Öktelik F; Istanbul University., Cetin EA; Istanbul University., Zhong Y; 1Division of Immunology, Boston Children's Hospital, Boston, Massachusetts, USA; 2Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Taylor M; 1Division of Immunology, Boston Children's Hospital, Boston, Massachusetts, USA; 2Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Irby K; Arkansas Children's Hospital., Halasa N; Vanderbilt University Medical Center., Signa S; DINOGMI, Università degli Studi di Genova, Genova, Italy and Center for Autoinflammatory Diseases and Immunodeficiencies, IRCCS Istituto Giannina Gaslini, Genova, Italy., Prigione I; Center for Autoinflammatory Diseases and Immunodeficiencies, IRCCS Istituto Giannina Gaslini, Genova, Italy., Gattorno M; Center for Autoinflammatory Diseases and Immunodeficiencies, IRCCS Istituto Giannina Gaslini, Genova, Italy., Cotugno N; Clinical and Research Unit of Clinical Immunology and Vaccinology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy, Chair of Pediatrics, Department of Systems Medicine, University., Amodio D; Clinical and Research Unit of Clinical Immunology and Vaccinology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Geha R; Childrens Hospital Boston/Harvard Medical School., Son MB; Boston Children's Hospital., Newburger J; Boston Children's Hospital., Agrawal P; Division of Newborn Medicine and Genetics & Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Volpi S; DINOGMI, Università degli Studi di Genova, Genova, Italy and Center for Autoinflammatory Diseases and Immunodeficiencies, IRCCS Istituto Giannina Gaslini, Genova, Italy., Palma P; Clinical and Research Unit of Clinical Immunology and Vaccinology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy, Chair of Pediatrics, Department of Systems Medicine, University., Kiykim A; Division of Pediatric Allergy and Immunology, Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey., Randolph A; Boston Children's Hospital., Deniz G; Istanbul University., Baris S; Marmara University, School of Medicine, Department of Pediatrics, Division of Allergy and Immunology, Istanbul., De Palma R; University of Genova., Schmitz-Abe K; 1Division of Immunology, Boston Children's Hospital, Boston, Massachusetts, USA; 2Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Charbonnier LM; Boston Children's Hospital, Boston., Henderson L; Boston Children's Hospital and Harvard Medical School.
Source: Research square [Res Sq] 2022 Apr 11. Date of Electronic Publication: 2022 Apr 11.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Notch1-CD22-Dependent Immune Dysregulation in the SARS-CoV2-Associated Multisystem Inflammatory Syndrome in Children.
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