Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification.

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Title: Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification.
Authors: Ho PJ; Genome Institute of Singapore, Human Genetics, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Ho WK; Cancer Research Malaysia, 1 Jalan SS12/1A, 47500, Subang Jaya, Selangor, Malaysia.; School of Mathematical Sciences, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, 43500, Semenyih, Selangor, Malaysia., Khng AJ; Genome Institute of Singapore, Human Genetics, Singapore, Singapore., Yeoh YS; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Tan BK; Department of General Surgery, Sengkang General Hospital, Singapore, Singapore.; Department of Breast Surgery, Singapore General Hospital, Singapore, Singapore.; Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Tan EY; Department of General Surgery, Tan Tock Seng Hospital, Singapore, 308433, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technology University, Singapore, Singapore.; Institute of Molecular and Cell Biology, Singapore, Singapore., Lim GH; KK Breast Department, KK Women's and Children's Hospital, Singapore, 229899, Singapore., Tan SM; Division of Breast Surgery, Changi General Hospital, Singapore, Singapore., Tan VKM; Department of Breast Surgery, Singapore General Hospital, Singapore, Singapore.; Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Yip CH; Subang Jaya Medical Centre, Subang Jaya, Selangor, Malaysia., Mohd-Taib NA; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.; Universiti Malaya Cancer Research Institute, Kuala Lumpur, Malaysia., Wong FY; Division of Radiation Oncology, National Cancer Centre Singapore, Singapore, Singapore., Lim EH; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Ngeow J; Lee Kong Chian School of Medicine, Nanyang Technology University, Singapore, Singapore.; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.; Cancer Genetics Service, National Cancer Centre Singapore, Singapore, Singapore., Chay WY; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Leong LCH; Department of Diagnostic Radiology, Singapore General Hospital, Singapore, Singapore., Yong WS; Division of Radiation Oncology, National Cancer Centre Singapore, Singapore, Singapore., Seah CM; Division of Breast Surgery, Changi General Hospital, Singapore, Singapore., Tang SW; Department of Surgery, University Surgical Cluster, National University Hospital, Singapore, Singapore., Ng CWQ; Department of Surgery, University Surgical Cluster, National University Hospital, Singapore, Singapore., Yan Z; KK Breast Department, KK Women's and Children's Hospital, Singapore, 229899, Singapore., Lee JA; KK Breast Department, KK Women's and Children's Hospital, Singapore, 229899, Singapore., Rahmat K; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Islam T; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.; Universiti Malaya Cancer Research Institute, Kuala Lumpur, Malaysia., Hassan T; Cancer Research Malaysia, 1 Jalan SS12/1A, 47500, Subang Jaya, Selangor, Malaysia., Tai MC; Cancer Research Malaysia, 1 Jalan SS12/1A, 47500, Subang Jaya, Selangor, Malaysia., Khor CC; Genome Institute of Singapore, Human Genetics, Singapore, Singapore., Yuan JM; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA., Koh WP; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Institute for Clinical Sciences, Agency for Science Technology and Research (A*STAR), Singapore, 117609, Singapore., Sim X; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Teo SH; Cancer Research Malaysia, 1 Jalan SS12/1A, 47500, Subang Jaya, Selangor, Malaysia.; Department of Surgery, Faculty of Medicine, University of Malaya, Jalan Universiti, 50630, Kuala Lumpur, Malaysia., Li J; Genome Institute of Singapore, Human Genetics, Singapore, Singapore. lijm1@gis.a-star.edu.sg.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore. lijm1@gis.a-star.edu.sg., Hartman M; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Surgery, University Surgical Cluster, National University Hospital, Singapore, Singapore.
Source: BMC medicine [BMC Med] 2022 Apr 26; Vol. 20 (1), pp. 150. Date of Electronic Publication: 2022 Apr 26.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015 (Electronic) Linking ISSN: 17417015 NLM ISO Abbreviation: BMC Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1741-7015
DOI:10.1186/s12916-022-02334-z