Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders.

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Title: Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders.
Authors: Zhang X; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Genomics and Computational Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Lucas AM; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Veturi Y; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Drivas TG; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Bone WP; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Genomics and Computational Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Verma A; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Chung WK; Department of Pediatrics and Medicine, Columbia University, New York, NY, 10032, USA., Crosslin D; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, 98109, USA., Denny JC; Department of Medicine, Vanderbilt University, Nashville, TN, 37235, USA.; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, 37230, USA., Hebbring S; Center for Human Genetics, Marshfield Clinic, Marshfield, WI, 54449, USA., Jarvik GP; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, 98109, USA., Kullo I; Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 55905, USA., Larson EB; Kaiser Permanente Washington Health Research Institute, Seattle, WA, 98101, USA., Rasmussen-Torvik LJ; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Schaid DJ; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 55905, USA., Smoller JW; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, 02114, USA., Stanaway IB; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, 98109, USA., Wei WQ; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, 37230, USA., Weng C; Department of Biomedical Informatics, Columbia University, New York, NY, 10032, USA., Ritchie MD; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. marylyn@pennmedicine.upenn.edu.
Source: Nature communications [Nat Commun] 2022 Jun 14; Vol. 13 (1), pp. 3428. Date of Electronic Publication: 2022 Jun 14.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Genomics and Computational Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Lucas+AM%22">Lucas AM</searchLink>; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Veturi+Y%22">Veturi Y</searchLink>; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Drivas+TG%22">Drivas TG</searchLink>; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Bone+WP%22">Bone WP</searchLink>; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Genomics and Computational Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Verma+A%22">Verma A</searchLink>; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Chung+WK%22">Chung WK</searchLink>; Department of Pediatrics and Medicine, Columbia University, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Crosslin+D%22">Crosslin D</searchLink>; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Denny+JC%22">Denny JC</searchLink>; Department of Medicine, Vanderbilt University, Nashville, TN, 37235, USA.; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, 37230, USA.<br /><searchLink fieldCode="AU" term="%22Hebbring+S%22">Hebbring S</searchLink>; Center for Human Genetics, Marshfield Clinic, Marshfield, WI, 54449, USA.<br /><searchLink fieldCode="AU" term="%22Jarvik+GP%22">Jarvik GP</searchLink>; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Kullo+I%22">Kullo I</searchLink>; Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Larson+EB%22">Larson EB</searchLink>; Kaiser Permanente Washington Health Research Institute, Seattle, WA, 98101, USA.<br /><searchLink fieldCode="AU" term="%22Rasmussen-Torvik+LJ%22">Rasmussen-Torvik LJ</searchLink>; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Schaid+DJ%22">Schaid DJ</searchLink>; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Smoller+JW%22">Smoller JW</searchLink>; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, 02114, USA.<br /><searchLink fieldCode="AU" term="%22Stanaway+IB%22">Stanaway IB</searchLink>; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Wei+WQ%22">Wei WQ</searchLink>; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, 37230, USA.<br /><searchLink fieldCode="AU" term="%22Weng+C%22">Weng C</searchLink>; Department of Biomedical Informatics, Columbia University, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Ritchie+MD%22">Ritchie MD</searchLink>; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. marylyn@pennmedicine.upenn.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Jun 14; Vol. 13 (1), pp. 3428. <i>Date of Electronic Publication: </i>2022 Jun 14.
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