SETDB1 acts as a topological accessory to Cohesin via an H3K9me3-independent, genomic shunt for regulating cell fates. - Warrier T; El Farran C; Zeng Y; Ho BSQ; Bao Q; Zheng ZH; Bi X; Ng HH; Ong DST; Chu JJH; Sanyal A; Fullwood MJ; et al. (Nucleic acids research, 2022)